Overview of our business
Zoetis is a global leader in the animal health industry, focused on the
discovery, development, manufacture and commercialization of medicines,
vaccines, diagnostic products, biodevices, genetic tests and precision livestock
farming technology. For nearly 70 years, we have been innovating ways to
predict, prevent, detect, and treat animal illness, and continue to stand by
those raising and caring for animals worldwide - from livestock farmers to
veterinarians and pet owners.
We manage our operations through two geographic operating segments: the United
States (U.S.) and International. Within each of these operating segments, we
offer a diversified product portfolio for both companion animal and livestock
customers in order to capitalize on local and regional trends and customer
needs. See Notes to Condensed Consolidated Financial Statements - Note 16.
Segment Information.
We directly market our products to veterinarians and livestock producers located
in approximately 45 countries across North America, Europe, Africa, Asia,
Australia and South America, and are a market leader in nearly all of the major
regions in which we operate. Through our efforts to establish an early and
direct presence in many emerging markets, such as Brazil, Chile, China and
Mexico, we believe we are one of the largest animal health medicines and
vaccines businesses as measured by revenue across emerging markets as a whole.
In markets where we do not have a direct commercial presence, we generally
contract with distributors that provide logistics and sales and marketing
support for our products.
We believe our investments in one of the industry's largest sales organizations,
including our extensive network of technical and veterinary operations
specialists, our high-quality manufacturing and reliability of supply, and our
long track record of developing products that meet customer needs, has led to
enduring and valued relationships with our customers. Our research and
development (R&D) efforts enable us to deliver innovative products to address
unmet needs and evolve our product lines so they remain relevant for our
customers.
Our products include over 300 products and product lines that we sell in over
100 countries for the prediction, prevention, detection and treatment of
diseases and conditions that affect various companion animal and livestock
species. The diversity of our product portfolio and our global operations
provides stability to our overall business. For instance, in livestock, impacts
on our revenue that may result from disease outbreaks or weather conditions in a
particular market or region are often offset by increased sales in other regions
from exports and other species as consumers shift to other proteins.
Beginning in the first quarter of 2021, certain costs associated with
information technology that specifically support our global manufacturing
operations, which were previously reported in Other unallocated, are now
reported in Corporate. In addition, in the first quarter of 2021, the company
realigned certain management responsibilities. These changes did not impact the
determination of our operating segments, however they resulted in the
reallocation of certain costs between segments. These changes primarily include
the following: (i) certain diagnostics costs, which were previously reported in
Corporate, are now reported in our U.S. results; and (ii) certain other
miscellaneous costs, which were previously reported in our U.S. results, are now
reported in Corporate.
Certain reclassifications of prior year information have been made to conform to
the current year's presentation.
A summary of our 2021 performance compared with the comparable 2020 period
follows:
                                                                                                                 % Change
                                                    Three Months Ended                                                  Related to
                                                      September 30,                                     Foreign
(MILLIONS OF DOLLARS)                             2021                2020            Total            Exchange                  Operational(a)
Revenue                                     $    1,990             $  1,786             11                     1                             10
Net income attributable to Zoetis                  552                  479             15                     5                             10
Adjusted net income(a)                             597                  524             14                     4                             10


                                                                                                              % Change
                                                   Nine Months Ended                                                 Related to
                                                     September 30,                                   Foreign
(MILLIONS OF DOLLARS)                           2021               2020            Total            Exchange                  Operational(a)
Revenue                                     $    5,809          $  4,868             19                     2                             17
Net income attributable to Zoetis                1,623             1,279             27                     3                             24
Adjusted net income(a)                           1,766             1,406             26                     3                             23


(a)  Operational growth and adjusted net income are non-GAAP financial measures.
See the Non-GAAP financial measures section of this Management's Discussion and
Analysis of Financial Condition and Results of Operations (MD&A) for more
information.
Our operating environment
For a description of our operating environment, including factors which could
materially affect our business, financial condition, or future results, see "Our
Operating Environment" in the MD&A of our 2020 Annual Report on Form 10-K. Set
forth below are updates to certain of the factors disclosed in our 2020 Form
10-K.

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Uncertainty Relating to COVID-19
We continue to closely monitor the impact of the coronavirus (COVID-19) pandemic
and the resulting global recession on all aspects of our business across
geographies, including how it has and may continue to impact our customers,
workforce, suppliers and vendors. Although we are unable to fully predict the
impact that the COVID-19 pandemic will ultimately have on our future financial
position and operating results, we continue to monitor the potential effects,
including impacts on our supply chain, the effect on customer demand, and
changes to our operations. We cannot predict the impact that the COVID-19
pandemic will have on our customers, vendors and suppliers; however, any
material effect on these parties could adversely impact us.
The situation surrounding COVID-19 remains fluid, and we will continue to
actively monitor the situation and may take actions that alter our business
operations that we determine are in the best interests of our workforce,
customers, vendors, suppliers, and other stakeholders, or as required by
federal, state, or local authorities.
For further information regarding the impact of COVID-19 on the Company, see
Item 1A, Risk Factors in this Quarterly Report on Form 10-Q.
Quarterly Variability of Financial Results
Our quarterly financial results are subject to variability related to a number
of factors including but not limited to: the impact of the COVID-19 pandemic
discussed above, weather patterns, herd management decisions, economic
conditions, regulatory actions, competitive dynamics, disease outbreaks, product
and geographic mix, timing of price increases and timing of investment
decisions.
Disease Outbreaks
Sales of our livestock products have in the past, and may in the future be,
adversely affected by the outbreak of disease carried by animals. Outbreaks of
disease may reduce regional or global sales of particular animal-derived food
products or result in reduced exports of such products, either due to heightened
export restrictions or import prohibitions, which may reduce demand for our
products. Also, the outbreak of any highly contagious disease near our main
production sites could require us to immediately halt production of our products
at such sites or force us to incur substantial expenses in procuring raw
materials or products elsewhere. Alternatively, sales of products that treat
specific disease outbreaks may increase.
Foreign Exchange Rates
Significant portions of our revenue and costs are exposed to changes in foreign
exchange rates. Our products are sold in more than 100 countries and, as a
result, our revenue is influenced by changes in foreign exchange rates. For the
nine months ended September 30, 2021, approximately 44% of our revenue was
denominated in foreign currencies. We seek to manage our foreign exchange risk,
in part, through operational means, including managing same-currency revenue in
relation to same-currency costs and same-currency assets in relation to
same-currency liabilities. As we operate in multiple foreign currencies,
including the euro, Chinese yuan, Brazilian real, Australian dollar, British
pound, Canadian dollar and other currencies, changes in those currencies
relative to the U.S. dollar will impact our revenue, cost of goods and expenses,
and consequently, net income. Exchange rate fluctuations may also have an impact
beyond our reported financial results and directly impact operations. These
fluctuations may affect the ability to buy and sell our goods and services
between markets impacted by significant exchange rate variances. For the nine
months ended September 30, 2021, approximately 56% of our total revenue was in
U.S. dollars. Our year-over-year total revenue growth was favorably impacted by
approximately 2% from changes in foreign currency values relative to the U.S.
dollar.
Non-GAAP financial measures
We report information in accordance with U.S. generally accepted accounting
principles (GAAP). Management also measures performance using non-GAAP financial
measures that may exclude certain amounts from the most directly comparable GAAP
financial measure. Despite the importance of these measures to management in
goal setting and performance measurement, non-GAAP financial measures have no
standardized meaning prescribed by U.S. GAAP and, therefore, have limits in
their usefulness to investors and may not be comparable to the calculation of
similar measures of other companies. We present certain identified non-GAAP
measures solely to provide investors with useful information to more fully
understand how management assesses performance.
Operational Growth
We believe that it is important to not only understand overall revenue and
earnings growth, but also "operational growth." Operational growth is a non-GAAP
financial measure defined as revenue or earnings growth excluding the impact of
foreign exchange. This measure provides information on the change in revenue and
earnings as if foreign currency exchange rates had not changed between the
current and prior periods to facilitate a period-to-period comparison. We
believe this non-GAAP measure provides a useful comparison to previous periods
for the company and investors, but should not be viewed as a substitute for U.S.
GAAP reported growth.
Adjusted Net Income and Adjusted Earnings Per Share
Adjusted net income and the corresponding adjusted earnings per share (EPS) are
non-GAAP financial measures of performance used by management. We believe these
financial measures are useful supplemental information to investors when
considered together with our U.S. GAAP financial measures. We report adjusted
net income to portray the results of our major operations, and the discovery,
development, manufacture and commercialization of our products, prior to
considering certain income statement elements. We define adjusted net income and
adjusted EPS as net income attributable to Zoetis and EPS before the impact of
purchase accounting adjustments, acquisition-related costs and certain
significant items.
We recognize that, as an internal measure of performance, the adjusted net
income and adjusted EPS measures have limitations, and we do not restrict our
performance management process solely to these metrics. A limitation of the
adjusted net income and adjusted EPS measures is that they provide a view of our
operations without including all events during a period, such as the effects of
an acquisition or amortization of purchased intangibles, and do not provide a
comparable view of our performance to other companies. The adjusted net income
and adjusted EPS measures are not, and should not be viewed as, a substitute for
U.S. GAAP reported net income and reported EPS. See the Adjusted Net Income
section below for more information.

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Analysis of the condensed consolidated statements of income
The following discussion and analysis of our statements of income should be read
along with our condensed consolidated financial statements and the notes thereto
included elsewhere in Part I- Item 1 of this Quarterly Report on Form 10-Q.
                                                      Three Months Ended                                     Nine Months Ended
                                                         September 30,                          %              September 30,                          %
(MILLIONS OF DOLLARS)                                2021              2020                Change          2021              2020                Change
Revenue                                          $   1,990          $ 1,786                 11          $  5,809          $ 4,868                 19
Costs and expenses:
Cost of sales                                          586              546                  7             1,703            1,456                 17
% of revenue                                          29.4  %          30.6  %                              29.3  %          29.9  %
Selling, general and administrative
expenses                                               504              424                 19             1,408            1,206                 17
% of revenue                                            25  %            24  %                                24  %            25  %
Research and development expenses                      132              112                 18               370              330                 12
% of revenue                                             7  %             6  %                                 6  %             7  %
Amortization of intangible assets                       40               40                  -               121              120                  1
Restructuring charges and certain
acquisition-related costs                                9                5                 80                39               22                 77
Interest expense, net of capitalized
interest                                                56               62                (10)              170              173                 (2)
Other (income)/deductions-net                            4                -                     *             16              (15)                    *
Income before provision for taxes on
income                                                 659              597                 10             1,982            1,576                 26
% of revenue                                            33  %            33  %                                34  %            32  %
Provision for taxes on income                          107              118                 (9)              361              298                 21
Effective tax rate                                    16.2  %          19.8  %                              18.2  %          18.9  %
Net income before allocation to
noncontrolling interests                               552              479                 15             1,621            1,278                 27
Less: Net loss attributable to
noncontrolling interests                                 -                -                  -                (2)              (1)                    *
Net income attributable to Zoetis Inc.           $     552          $   479                 15          $  1,623          $ 1,279                 27
% of revenue                                            28  %            27  %                                28  %            26  %


*Calculation not meaningful
Revenue
Three months ended September 30, 2021 vs. three months ended September 30, 2020
Total revenue increased by $204 million, or 11%, in the three months ended
September 30, 2021, compared with the three months ended September 30, 2020, an
increase of $176 million, or 10%, on an operational basis. Operational revenue
growth was comprised primarily of the following:
•volume growth from new products of approximately 5%;
•volume growth from in-line products, including key dermatology products, of
approximately 3%; and
•price growth of approximately 2%.
Foreign exchange increased reported revenue growth by approximately 1%.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Total revenue increased by $941 million, or 19%, in the nine months ended
September 30, 2021, compared with the nine months ended September 30, 2020, an
increase of $843 million, or 17%, on an operational basis. Operational revenue
growth was comprised primarily of the following:
•volume growth from in-line products, including key dermatology products, of
approximately 11%;
•volume growth from new products of approximately 5%; and
•price growth of approximately 1%.
Foreign exchange increased reported revenue growth by approximately 2%.

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Costs and Expenses
Cost of sales
                                 Three Months Ended                          Nine Months Ended
                                   September 30,                    %          September 30,                 %
(MILLIONS OF DOLLARS)          2021                2020        Change       2021           2020         Change
Cost of sales              $    586              $ 546            7      $  1,703       $ 1,456           17
% of revenue                   29.4   %           30.6  %                    29.3  %       29.9  %


Three months ended September 30, 2021 vs. three months ended September 30, 2020
Cost of sales as a percentage of revenue was 29.4% in the three months ended
September 30, 2021 compared with 30.6% in the three months ended September 30,
2020. The decrease was primarily as a result of:
•favorable product mix;
•favorable foreign exchange;
•lower inventory obsolescence, scrap and other charges; and
•price growth,
partially offset by:
•unfavorable manufacturing and other costs; and
•higher freight and import costs.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Cost of sales as a percentage of revenue was 29.3% in the nine months ended
September 30, 2021 compared with 29.9% in the nine months ended September 30,
2020. The decrease was primarily as a result of:
•favorable product mix;
•lower inventory obsolescence, scrap and other charges;
•price growth; and
•favorable foreign exchange,
partially offset by:
•unfavorable manufacturing costs and other costs; and
•higher freight and import costs.
Selling, general and administrative expenses
                                                  Three Months Ended                                       Nine Months Ended
                                                    September 30,                             %              September 30,                          %
(MILLIONS OF DOLLARS)                         2021                   2020                Change          2021              2020                Change
Selling, general and administrative
expenses                                  $    504                $   424                 19          $  1,408          $ 1,206                 17
% of revenue                                    25   %                 24  %                                24  %            25  %


Three months ended September 30, 2021 vs. three months ended September 30, 2020
SG&A expenses increased by $80 million, or 19%, in the three months ended
September 30, 2021, compared with the three months ended September 30, 2020,
primarily as a result of:
•an increase in certain compensation-related costs;
•investments to support revenue growth;
•higher freight and logistics costs;
•higher travel and entertainment due to a reduction in COVID-19 related
restrictions; and
•unfavorable foreign exchange,
partially offset by:
•the reduced impact of certain significant items and purchase accounting
adjustments.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
SG&A expenses increased by $202 million, or 17%, in the nine months ended
September 30, 2021, compared with the nine months ended September 30, 2020,
primarily as a result of:
•an increase in certain compensation-related costs;
•investments to support revenue growth;
•unfavorable foreign exchange; and
•higher freight and logistics costs,
partially offset by:
•the reduced impact of purchase accounting adjustments and certain significant
items; and
•lower travel and entertainment expenses as a result of decreases in travel and
events related to the COVID-19 pandemic.

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Research and development
expenses
                                               Three Months Ended                                          Nine Months Ended
                                                 September 30,                             %                 September 30,                            %
(MILLIONS OF DOLLARS)                      2021                   2020                Change           2021                  2020                Change
Research and development
expenses                               $    132                $   112                 18          $    370               $   330                 12
% of revenue                                  7   %                  6  %                                 6   %                 7  %


Three months ended September 30, 2021 vs. three months ended September 30, 2020
R&D expenses increased by $20 million, or 18%, in the three months ended
September 30, 2021, compared with the three months ended September 30, 2020,
primarily as a result of:
•increased spending driven by project investments;
•increase in certain compensation-related costs to support innovation; and
•unfavorable foreign exchange.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
R&D expenses increased by $40 million, or 12%, in the nine months ended
September 30, 2021, compared with the nine months ended September 30, 2020,
primarily as a result of:
•an increase in certain compensation-related costs to support innovation;
•increased spending driven by project investments; and
•unfavorable foreign exchange.
partially offset by:
•lower travel and entertainment expenses as a result of decreases in travel and
events related to the COVID-19 pandemic.
Amortization of intangible assets
                                              Three Months Ended                                      Nine Months Ended
                                                September 30,                           %               September 30,                          %
(MILLIONS OF DOLLARS)                       2021               2020                Change           2021              2020                Change

Amortization of intangible assets $ 40 $ 40

          -          $     121          $   120                  1



Restructuring charges and certain acquisition-related costs


                                                           Three Months Ended                                       Nine Months Ended
                                                             September 30,                            %               September 30,                           %
(MILLIONS OF DOLLARS)                                    2021               2020                 Change           2021               2020                Change
Restructuring charges and certain
acquisition-related costs                           $       9            $      5                 80          $       39          $    22                 77


*Calculation not meaningful
Our acquisition-related costs primarily relate to restructuring charges for
employees, assets and activities that will not continue in the future, as well
as integration costs. Net restructuring charges are primarily related to asset
impairment charges, employee termination costs and exit costs. Our integration
costs are generally comprised of consulting costs related to the integration of
systems and processes, as well as product transfer costs.
For additional information regarding restructuring charges and
acquisition-related costs, see Notes to Condensed Consolidated Financial
Statements- Note 6. Restructuring Charges and Other Costs Associated with
Acquisitions, Cost-Reduction and Productivity Initiatives.
Three months ended September 30, 2021 vs. three months ended September 30, 2020
Restructuring charges and certain acquisition-related costs were $9 million and
$5 million in the three months ended September 30, 2021 and 2020, respectively.
Restructuring charges and certain acquisition-related costs in the three months
ended September 30, 2021 primarily consisted of employee termination costs
associated with the realignment of our international operations. Restructuring
charges and certain acquisition-related costs in the three months ended
September 30, 2020 consisted of employee termination costs related to other
cost-reduction and productivity initiatives and integration costs related to
acquisitions.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Restructuring charges and certain acquisition-related costs were $39 million and
$22 million in the nine months ended September 30, 2021 and 2020, respectively.
Restructuring charges and certain acquisition-related costs in the nine months
ended September 30, 2021 primarily consisted of employee termination costs
associated with our international operations and other costs associated with
cost-reduction and productivity initiatives, asset impairment charges related to
the consolidation of manufacturing sites in China and integration costs related
to recent acquisitions. Restructuring charges and certain acquisition-related
costs in the nine months ended September 30, 2020 consisted of integration costs
related to acquisitions, restructuring charges related to CEO transition-related
costs and employee termination costs related to other cost-reduction and
productivity initiatives.

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Interest expense, net of capitalized interest
                                                  Three Months Ended                                      Nine Months Ended
                                                    September 30,                           %               September 30,                          %
(MILLIONS OF DOLLARS)                           2021               2020                Change           2021              2020                Change
Interest expense, net of capitalized
interest                                    $       56          $    62                (10)         $     170          $   173                 (2)


Three months ended September 30, 2021 vs. three months ended September 30, 2020
Interest expense, net of capitalized interest, decreased by 10% in the three
months ended September 30, 2021, compared with the three months ended September
30, 2020, primarily as a result of the redemption of $500 million aggregate
principal amount of our senior notes in October 2020, as well as the redemption
of our $300 million aggregate principal amount of our 2018 floating rate senior
notes and the $300 million aggregate principal amount of our 2018 senior notes
in August 2021.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Interest expense, net of capitalized interest, decreased by 2% in the nine
months ended September 30, 2021, compared with the nine months ended September
30, 2020, primarily as a result of the redemption of $500 million aggregate
principal amount of our senior notes in October 2020, as well as the redemption
of our $300 million aggregate principal amount of our 2018 floating rate senior
notes and the $300 million aggregate principal amount of our 2018 senior notes
in August 2021, partially offset by the issuance of $1.25 billion aggregate
principal amount of our senior notes in May 2020 and lower gains on
cross-currency interest rate swaps as compared to the prior year period.
Other (income)/deductions-net
                                                           Three Months Ended                                      Nine Months Ended
                                                             September 30,                            %              September 30,                          %
(MILLIONS OF DOLLARS)                                    2021               2020                 Change          2021              2020                Change
Other (income)/deductions-net                       $       4            $      -                     *       $     16          $   (15)                    *


*Calculation not meaningful
Three months ended September 30, 2021 vs. three months ended September 30, 2020
The change in Other (income)/deductions-net is primarily as a result of higher
foreign currency losses and asset impairment charges related to a dairy product
termination.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
The change in Other (income)/deductions-net is primarily as a result of a net
gain of $17 million related to a cash payment received pursuant to an agreement
related to the 2016 sale of certain U.S. manufacturing sites in the prior year
period, higher foreign currency losses, lower interest income, asset impairment
charges related to a dairy product termination and a net loss related to the
sale of certain assets of our poultry automation business located in the U.S.
and Canada, partially offset by an impairment of an equity investment and asset
impairment charges incurred in the prior year period.
Provision for taxes on income
                                              Three Months Ended                                          Nine Months Ended
                                                September 30,                             %                 September 30,                            %
(MILLIONS OF DOLLARS)                     2021                   2020                Change           2021                  2020                Change
Provision for taxes on income         $    107                $   118                 (9)         $    361               $   298                 21
Effective tax rate                        16.2   %               19.8  %                              18.2   %              18.9  %


Three months ended September 30, 2021 vs. three months ended September 30, 2020
Our effective tax rate was 16.2% for the three months ended September 30, 2021,
compared with 19.8% for the three months ended September 30, 2020. The lower
effective tax rate for the three months ended September 30, 2021, was primarily
attributable to:
•changes in the jurisdictional mix of earnings, which includes the impact of the
location of earnings from operations and repatriation costs. The jurisdictional
mix of earnings can vary as a result of repatriation decisions, operating
fluctuations in the normal course of business and the impact of non-deductible
items and non-taxable items. In addition, the three months ended September 30,
2021 includes a tax benefit related to foreign-derived intangible income; and
•a $4 million discrete tax benefit recorded in the three months ended September
30, 2021, related to the effective settlement of certain issues with tax
authorities.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Our effective tax rate was 18.2% for the nine months ended September 30, 2021,
compared with 18.9% for the nine months ended September 30, 2020. The lower
effective tax rate for the nine months ended September 30, 2021 was primarily
attributable to:
•changes in the jurisdictional mix of earnings, which includes the impact of the
location of earnings from operations and repatriation costs. The jurisdictional
mix of earnings can vary as a result of repatriation decisions, operating
fluctuations in the normal course of business and the impact of non-deductible
items and non-taxable items. In addition, the nine months ended September 30,
2021 includes a tax benefit related to foreign-derived intangible income; and

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•a $4 million discrete tax benefit recorded in the nine months ended September
30, 2021, related to the effective settlement of certain issues with tax
authorities,
partially offset by:
•a $21 million and a $29 million discrete tax benefit recorded in the nine
months ended September 30, 2021 and 2020, respectively, related to the excess
tax benefits for share-based payments; and
•a $7 million discrete tax benefit recorded in the nine months ended September
30, 2020, related to a remeasurement of deferred taxes resulting from the
integration of acquired businesses.
Operating Segment Results
On a global basis, the mix of revenue between companion animal and livestock
products was as follows:
                                                                                                                  % Change
                                                  Three Months Ended                                                         Related to
                                                     September 30,                                            Foreign
(MILLIONS OF DOLLARS)                            2021                2020             Total                   Exchange                  Operational
U.S.
Companion animal                           $      775             $   664                17                         -                            17
Livestock                                         290                 332               (13)                        -                           (13)
                                                1,065                 996                 7                         -                             7
International
Companion animal                                  427                 331                29                         5                            24
Livestock                                         477                 436                 9                         2                             7
                                                  904                 767                18                         4                            14
Total
Companion animal                                1,202                 995                21                         2                            19
Livestock                                         767                 768                 -                         2                            (2)
Contract manufacturing & human
health                                             21                  23                (9)                        -                            (9)
                                           $    1,990             $ 1,786                11                         1                            10


                                                                                                               % Change
                                                 Nine Months Ended                                                        Related to
                                                   September 30,                                           Foreign
(MILLIONS OF DOLLARS)                          2021               2020             Total                   Exchange                  Operational
U.S.
Companion animal                           $    2,227          $ 1,757                27                         -                            27
Livestock                                         775              848                (9)                        -                            (9)
                                                3,002            2,605                15                         -                            15
International
Companion animal                                1,280              917                40                         7                            33
Livestock                                       1,470            1,286                14                         3                            11
                                                2,750            2,203                25                         5                            20
Total
Companion animal                                3,507            2,674                31                         2                            29
Livestock                                       2,245            2,134                 5                         2                             3
Contract manufacturing & human
health                                             57               60                (5)                        1                            (6)
                                           $    5,809          $ 4,868                19                         2                            17



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Earnings by segment and the operational and foreign exchange changes versus the
comparable prior year period were as follows:
                                                                                                                              % Change
                                                               Three Months Ended                                                        Related to
                                                                 September 30,                                            Foreign
(MILLIONS OF DOLLARS)                                        2021          

    2020              Total                   Exchange                  Operational
U.S.:
Revenue                                                 $    1,065           $    996                 7                         -                             7
Cost of Sales                                                  199                194                 3                         -                             3
Gross Profit                                                   866                802                 8                         -                             8
Gross Margin                                                  81.3   %           80.5  %
Operating Expenses                                             183                157                17                         -                            17
Other (income)/deductions-net                                    -                  -                    *                          *                               *
U.S. Earnings                                                  683                645                 6                         -                             6

International:
Revenue                                                        904                767                18                         4                            14
Cost of Sales                                                  273                245                11                        (1)                           12
Gross Profit                                                   631                522                21                         5                            16
Gross Margin                                                  69.8   %           68.1  %
Operating Expenses                                             152                122                25                         4                            21
Other (income)/deductions-net                                   (4)                 -                    *                          *                               *
International Earnings                                         483                400                21                         6                            15

Total operating segments                                     1,166              1,045                12                         3                             9

Other business activities                                     (106)               (87)               22
Reconciling Items:
Corporate                                                     (252)              (222)               14
Purchase accounting adjustments                                (45)               (48)               (6)
Acquisition-related costs                                       (1)                (1)                -
Certain significant items                                      (12)                (9)               33
Other unallocated                                              (91)               (81)               12
Total Earnings                                          $      659           $    597                10


                                                                                                                           % Change
                                                              Nine Months Ended                                                       Related to
                                                                September 30,                                          Foreign
(MILLIONS OF DOLLARS)                                       2021              2020             Total                   Exchange                  Operational
U.S.:
Revenue                                                 $   3,002          $ 2,605                15                         -                            15
Cost of Sales                                                 575              515                12                         -                            12
Gross Profit                                                2,427            2,090                16                         -                            16
Gross Margin                                                 80.8  %          80.2  %
Operating Expenses                                            484              418                16                         -                            16
Other (income)/deductions-net                                   2                4               (50)                        -                           (50)
U.S. Earnings                                               1,941            1,668                16                         -                            16

International:
Revenue                                                     2,750            2,203                25                         5                            20
Cost of Sales                                                 833              697                20                         2                            18
Gross Profit                                                1,917            1,506                27                         5                            22
Gross Margin                                                 69.7  %          68.4  %
Operating Expenses                                            429              364                18                         5                            13
Other (income)/deductions-net                                  (4)               1                    *                          *                               *
International Earnings                                      1,492            1,141                31                         6                            25

Total operating segments                                    3,433            2,809                22                         2                            20

Other business activities                                    (301)            (264)               14
Reconciling Items:
Corporate                                                    (744)            (603)               23
Purchase accounting adjustments                              (133)            (155)              (14)
Acquisition-related costs                                      (8)             (15)              (47)
Certain significant items                                     (44)              (4)                   *
Other unallocated                                            (221)            (192)               15
Total Earnings                                          $   1,982          $ 1,576                26


* Calculation not meaningful.
Three months ended September 30, 2021 vs. three months ended September 30, 2020
U.S. operating segment
U.S. segment revenue increased by $69 million, or 7%, in the three months ended
September 30, 2021, compared with the three months ended September 30, 2020,
reflecting an increase of approximately $111 million in companion animal
products, partially offset by a decrease of approximately $42 million in
livestock products.
•Companion animal revenue growth was driven primarily by increased sales of
parasiticides, including Simparica Trio®, our new triple combination
parasiticide. In-line products growth benefited from increased sales of our key
dermatology portfolio.
•Livestock revenue declined primarily due to decreased sales in cattle, poultry
and swine. Cattle product sales declined as a result of increased generic
competition and last year's earlier cattle run now expected to occur in the
fourth quarter this year, as well as challenges in the beef and dairy
end-markets due to rising input costs. The poultry portfolio declined as a
result of smaller flock sizes reducing disease pressure, the expanded use of
lower cost alternatives and generic competition. Swine product sales declined
primarily due to pricing pressures on our anti-infective and vaccine portfolio.
U.S. segment earnings increased by $38 million, or 6%, in the three months ended
September 30, 2021, compared with the three months ended September 30, 2020,
primarily due to revenue and gross margin growth, partially offset by higher
operating expenses.
International operating segment
International segment revenue increased by $137 million, or 18%, in the three
months ended September 30, 2021, compared with the three months ended September
30, 2020. Operational revenue increased by $109 million, or 14%, driven by
growth of approximately $80 million in companion animal products and $29 million
in livestock products.
•Companion animal operational revenue growth was driven primarily by increased
sales across the broader in-line portfolio, including our key dermatology
portfolio, which benefited from increased pet ownership and standards of care.
Growth also resulted from sales of our parasiticide products, including the
Simparica® and Revolution®/Stronghold® franchises. The recent launches of our
monoclonal antibody (mAb) therapies, Librela® and Solensia® also contributed to
growth.

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•Livestock operational revenue growth was driven by increased sales in cattle,
fish, swine and poultry. Cattle product sales increased due to key account
penetration, favorable export market conditions in Brazil and favorable
conditions in other emerging markets. Growth in the fish portfolio resulted
primarily from increased sales of the Alpha Flux® sea lice treatment product and
an increase in vaccine sales in key salmon markets. Sales of both swine and
poultry products grew as a result of key account growth and market expansion
across parts of Asia, Brazil and Russia.
•Additionally, International segment revenue was favorably impacted by foreign
exchange which increased revenue by approximately $28 million, or 4%, primarily
driven by the euro, Chinese yuan, British pound and Canadian dollar, partially
offset by the Argentinian peso.
International segment earnings increased by $83 million, or 21%, in the three
months ended September 30, 2021, compared with the three months ended September
30, 2020. Operational earnings growth was $60 million, or 15%, primarily due to
revenue and gross margin growth, partially offset by higher operating expenses.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
U.S. operating segment
U.S. segment revenue increased by $397 million, or 15%, in the nine months ended
September 30, 2021, compared with the nine months ended September 30, 2020,
reflecting an increase of approximately $470 million in companion animal
products, partially offset by a decrease of approximately $73 million in
livestock products.
•Companion animal revenue growth was driven primarily by increased sales of
parasiticides, including Simparica Trio, as well as the ProHeart and
Revolution/Stronghold franchises. In-line product growth benefited from
increased sales of our key dermatology portfolio, diagnostics products and
vaccines.
•Livestock revenue declined due to poultry, cattle and swine. The poultry
portfolio declined as a result of the expanded use of lower cost alternatives,
smaller flock sizes reducing disease pressure, as well as generic competition.
Cattle product sales declined as a result of increased generic competition and
challenges in the beef and dairy end-markets due to rising input costs, as well
as last year's earlier fall cattle run now expected to occur in the fourth
quarter this year. The decline in swine product sales was primarily due to
pricing pressures on our anti-infective and vaccine portfolio and a
non-recurring government purchase in the prior year.
U.S. segment earnings increased by $273 million, or 16%, in the nine months
ended September 30, 2021, compared with the nine months ended September 30,
2020, primarily due to revenue and gross margin growth, partially offset by
higher operating expenses.
International operating segment
International segment revenue increased by $547 million, or 25%, in the nine
months ended September 30, 2021, compared with the nine months ended September
30, 2020. Operational revenue increased by $449 million, or 20%, driven by
growth of approximately $306 million in companion animal products and $143
million in livestock products.
•Companion animal operational revenue growth was driven primarily by increased
sales of our parasiticide products, including the Simparica and
Revolution/Stronghold franchises. Also contributing to growth were our key
dermatology portfolio, vaccine products and diagnostic products, as well as the
recent launches of our mAb therapies, Librela and Solensia. Growth across the
broader in-line portfolio benefited from increased pet ownership and standards
of care.
•Livestock operational revenue growth was primarily driven by increased sales in
cattle, swine and fish. Growth in cattle product sales was mainly due to the
effect of marketing campaigns, key account penetration and favorable export
market conditions in Brazil and favorable conditions in other emerging markets.
Sales of swine products grew as a result of expanding production in the wake of
African Swine Fever in China in the first half of the year. Fish growth was due
to an increase in sales of the Alpha Flux sea lice treatment product, an
increase in vaccine sales in key salmon markets and the recent acquisition of
Fish Vet Group.
•Additionally, International segment revenue was favorably impacted by foreign
exchange which increased revenue by approximately $98 million, or 5%, primarily
driven by the euro, Australian dollar, Chinese yuan and Canadian dollar,
partially offset by the Brazilian real and Argentinian peso.
International segment earnings increased by $351 million, or 31%, in the nine
months ended September 30, 2021, compared with the nine months ended September
30, 2020. Operational earnings growth was $283 million, or 25%, primarily due to
revenue and gross margin growth, partially offset by higher operating expenses.
Other business activities
Other business activities includes our Client Supply Services (CSS) contract
manufacturing results, our human health business and expenses associated with
our dedicated veterinary medicine research and development organization,
research alliances, U.S. regulatory affairs and other operations focused on the
development of our products. Other R&D-related costs associated with non-U.S.
market and regulatory activities are generally included in the International
segment.
Three months ended September 30, 2021 vs. three months ended September 30, 2020
Other business activities net loss increased by $19 million in the three months
ended September 30, 2021, compared with the three months ended September 30,
2020, reflecting an increase in R&D costs due to an increase in project
investments, certain compensation-related costs and unfavorable foreign
exchange.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Other business activities net loss increased by $37 million in the nine months
ended September 30, 2021, compared with the nine months ended September 30,
2020, reflecting an increase in R&D costs due to an increase in certain
compensation-related costs, an increase in project investments and unfavorable
foreign exchange, partially offset by lower travel and entertainment expenses as
a result of decreases in travel and events related to the COVID-19 pandemic.

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Reconciling items
Reconciling items include certain costs that are not allocated to our operating
segments results, such as costs associated with the following:
•Corporate, which includes certain costs associated with information technology,
facilities, legal, finance, human resources, business development and
communications, among others. These costs also include certain compensation
costs, certain procurement costs, and other miscellaneous operating expenses
that are not charged to our operating segments, as well as interest income and
expense;
•Certain transactions and events such as (i) Purchase accounting adjustments,
which includes expenses associated with the amortization of fair value
adjustments to inventory, intangible assets, and property, plant and equipment;
(ii) Acquisition-related activities, which includes costs for acquisition and
integration; and (iii) Certain significant items, which includes
non-acquisition-related restructuring charges, certain asset impairment charges,
certain legal and commercial settlements, and costs associated with cost
reduction/productivity initiatives; and
•Other unallocated, which includes (i) certain overhead expenses associated with
our global manufacturing operations not charged to our operating segments; (ii)
certain costs associated with finance that specifically support our global
manufacturing operations; (iii) certain supply chain and global logistics costs;
and (iv) certain procurement costs.
Three months ended September 30, 2021 vs. three months ended September 30, 2020
Corporate expenses increased by $30 million, or 14%, in the three months ended
September 30, 2021, compared with the three months ended September 30, 2020,
primarily due to an increase in certain compensation-related costs and
investments in information technology, partially offset by lower interest
expense.
Other unallocated expenses increased by $10 million, or 12%, in the three months
ended September 30, 2021, compared with the three months ended September 30,
2020, primarily due to higher manufacturing costs and higher freight charges,
partially offset by lower inventory obsolescence, scrap and other charges.
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Corporate expenses increased by $141 million, or 23%, in the nine months ended
September 30, 2021, compared with the nine months ended September 30, 2020,
primarily due to an increase in certain compensation-related costs, investments
in information technology, unfavorable foreign exchange and lower interest
income, partially offset by lower interest expense.
Other unallocated expenses increased by $29 million, or 15%, in the nine months
ended September 30, 2021, compared with the nine months ended September 30,
2020, primarily due to higher manufacturing costs, higher freight charges and
unfavorable foreign exchange, partially offset by lower inventory obsolescence,
scrap and other charges.
See Notes to Condensed Consolidated Financial Statements-Note 16. Segment
Information for further information.
Adjusted net income
General description of adjusted net income (a non-GAAP financial measure)
Adjusted net income is an alternative view of performance used by management,
and we believe that investors' understanding of our performance is enhanced by
disclosing this performance measure. The adjusted net income measure is an
important internal measurement for us. Additionally, we measure our overall
performance on this basis in conjunction with other performance metrics. The
following are examples of how the adjusted net income measure is utilized:
•senior management receives a monthly analysis of our operating results that is
prepared on an adjusted net income basis;
•our annual budgets are prepared on an adjusted net income basis; and
•other goal setting and performance measurements.
Purchase accounting adjustments
Adjusted net income is calculated prior to considering certain significant
purchase accounting impacts that result from business combinations and net asset
acquisitions. These impacts, primarily associated with the acquisition of Abaxis
(acquired in July 2018), the Pharmaq business (acquired in November 2015),
certain assets of Abbott Animal Health (acquired in February 2015), King Animal
Health (KAH) (acquired in 2011), Fort Dodge Animal Health (FDAH) (acquired in
2009), and Pharmacia Animal Health business (acquired in 2003), include
amortization related to the increase in fair value of the acquired finite-lived
intangible assets and depreciation related to the increase/decrease to fair
value of the acquired fixed assets. Therefore, the adjusted net income measure
includes the revenue earned upon the sale of the acquired products without
considering the aforementioned significant charges.
While certain purchase accounting adjustments can occur through 20 or more
years, this presentation provides an alternative view of our performance that is
used by management to internally assess business performance. We believe the
elimination of amortization attributable to acquired intangible assets provides
management and investors an alternative view of our business results by
providing a degree of parity to internally developed intangible assets for which
R&D costs previously have been expensed.
A completely accurate comparison of internally developed intangible assets and
acquired intangible assets cannot be achieved through adjusted net income. These
components of adjusted net income are derived solely from the impact of the
items listed above. We have not factored in the impact of any other differences
in experience that might have occurred if we had discovered and developed those
intangible assets on our own, and this approach does not intend to be
representative of the results that would have occurred in those circumstances.
For example, our R&D costs in total, and in the periods presented, may have been
different; our speed to commercialization and resulting revenue, if any, may
have been different; or our costs to manufacture may have been different. In
addition, our marketing efforts may have been received differently by our
customers. As such, in total, there can be no assurance that our adjusted net
income amounts would have been the same as presented had we discovered and
developed the acquired intangible assets.

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Acquisition-related costs
Adjusted net income is calculated prior to considering transaction and
integration costs associated with significant business combinations or net asset
acquisitions because these costs are unique to each transaction and represent
costs that were incurred to acquire and integrate certain businesses as a result
of the acquisition decision. We have made no adjustments for the resulting
synergies.
We believe that viewing income prior to considering these charges provides
investors with a useful additional perspective because the significant costs
incurred in a business combination result primarily from the need to eliminate
duplicate assets, activities or employees--a natural result of acquiring a fully
integrated set of activities. For this reason, we believe that the costs
incurred to convert disparate systems, to close duplicative facilities or to
eliminate duplicate positions (for example, in the context of a business
combination) can be viewed differently from those costs incurred in the ordinary
course of business.
The integration costs associated with a business combination may occur over
several years, with the more significant impacts generally ending within three
years of the transaction. Because of the need for certain external approvals for
some actions, the span of time needed to achieve certain restructuring and
integration activities can be lengthy. For example, due to the regulated nature
of the animal health medicines, vaccines and diagnostics business, the closure
of excess facilities can take several years, as all manufacturing changes are
subject to extensive validation and testing and must be approved by the U.S.
Food and Drug Administration and/or other regulatory authorities.
Certain significant items
Adjusted net income is calculated excluding certain significant items. Certain
significant items represent substantive, unusual items that are evaluated on an
individual basis. Such evaluation considers both the quantitative and the
qualitative aspect of their unusual nature. Unusual, in this context, may
represent items that are not part of our ongoing business; items that, either as
a result of their nature or size, we would not expect to occur as part of our
normal business on a regular basis; items that would be nonrecurring; or items
that relate to products that we no longer sell. While not all-inclusive,
examples of items that could be included as certain significant items would be
costs related to a major non-acquisition-related restructuring charge and
associated implementation costs for a program that is specific in nature with a
defined term, such as those related to our non-acquisition-related
cost-reduction and productivity initiatives; amounts related to disposals of
products or facilities that do not qualify as discontinued operations as defined
by U.S. GAAP; certain intangible asset impairments; adjustments related to the
resolution of certain tax positions; significant currency devaluation; the
impact of adopting certain significant, event-driven tax legislation; or charges
related to legal matters. See Notes to Condensed Consolidated Financial
Statements- Note 15. Commitments and Contingencies. Our normal, ongoing defense
costs or settlements of and accruals on legal matters made in the normal course
of our business would not be considered certain significant items.
Reconciliation
A reconciliation of net income, as reported under U.S. GAAP, to adjusted net
income follows:
                                                      Three Months Ended                                      Nine Months Ended
                                                         September 30,                          %               September 30,                     %
(MILLIONS OF DOLLARS)                                2021              2020                Change           2021               2020             Change
GAAP reported net income attributable to
Zoetis                                           $      552          $  479                 15          $    1,623          $ 1,279                 27
Purchase accounting adjustments-net of tax               35              37                 (5)                103              108                 (5)
Acquisition-related costs-net of tax                      1               1                  -                   7               15                (53)
Certain significant items-net of tax                      9               7                 29                  33                4                     *
Non-GAAP adjusted net income(a)                  $      597          $  524                 14          $    1,766          $ 1,406                 26


*Calculation not meaningful.
(a)  The effective tax rate on adjusted pretax income is 16.7% and 20.0% for the
three months ended September 30, 2021 and 2020, respectively. The lower
effective tax rate for the three months ended September 30, 2021, compared with
the three months ended September 30, 2020, was primarily attributable to (i)
changes in the jurisdictional mix of earnings, which includes the impact of the
location of earnings, repatriation costs, operating fluctuations in the normal
course of business and the impact of non-deductible and non-taxable items. In
addition, the three months ended September 30, 2021 includes a tax benefit
related to foreign-derived intangible income, and (ii) a $4 million discrete tax
benefit recorded in the three months ended September 30, 2021, related to the
effective settlement of certain issues with tax authorities.
The effective tax rate on adjusted pretax income is 18.6% and 19.7% for the nine
months ended September 30, 2021 and 2020, respectively. The lower effective tax
rate for the nine months ended September 30, 2021, compared with the nine months
ended September 30, 2020, was primarily attributable to (i) changes in the
jurisdictional mix of earnings, which includes the impact of the location of
earnings, repatriation costs, operating fluctuations in the normal course of
business and the impact of non-deductible and non-taxable items. In addition,
the nine months ended September 30, 2021 includes a tax benefit related to
foreign-derived intangible income, and (ii) a $4 million discrete tax benefit
recorded in the nine months ended September 30, 2021, related to the effective
settlement of certain issues with tax authorities, partially offset by a $21
million and $29 million discrete tax benefit recorded in the nine months ended
September 30, 2021 and 2020, respectively, related to the excess tax benefits
for share-based payments.

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A reconciliation of reported diluted earnings per share (EPS), as reported under
U.S. GAAP, to non-GAAP adjusted diluted EPS follows:
                                                          Three Months Ended                                          Nine Months Ended
                                                            September 30,                             %                 September 30,                            %
                                                         2021                2020                Change             2021                2020                Change
Earnings per share-diluted(a):
GAAP reported EPS attributable to Zoetis
-diluted                                          $     1.16               $ 1.00                 16          $     3.40              $ 2.67

27


Purchase accounting adjustments-net of tax              0.07                 0.08                (13)               0.22                0.23            

(4)


Acquisition-related costs-net of tax                       -                    -                     *             0.01                0.03           

(67)


Certain significant items-net of tax                    0.02                 0.02                  -                0.07                0.01            

*


Non-GAAP adjusted EPS-diluted                     $     1.25               $ 1.10                 14          $     3.70              $ 2.94

26




* Calculation not meaningful.
(a)  Diluted earnings per share was computed using the weighted-average common
shares outstanding during the period plus the common stock equivalents related
to stock options, restricted stock units, performance-vesting restricted stock
units and deferred stock units.
Adjusted net income includes the following charges for each of the periods
presented:
                                                      Three Months Ended                      Nine Months Ended
                                                         September 30,                          September 30,
(MILLIONS OF DOLLARS)                               2021                2020               2021                2020
Interest expense, net of capitalized
interest                                       $        56          $      62          $      170          $     173
Interest income                                          1                  1                   4                  9
Income taxes                                           120                131                 403                345
Depreciation                                            56                 53                 171                148
Amortization                                             9                 10                  27                 29

Adjusted net income, as shown above, excludes the following items:


                                                                Three Months Ended                      Nine Months Ended
                                                                   September 30,                          September 30,
(MILLIONS OF DOLLARS)                                         2021                2020               2021                2020
Purchase accounting adjustments:
Amortization and depreciation(a)                         $        45

$ 48 $ 133 $ 155



Total purchase accounting adjustments-pre-tax                     45                 48                 133                155
Income taxes(b)                                                   10                 11                  30                 47
Total purchase accounting adjustments-net of tax                  35                 37                 103                108
Acquisition-related costs:

Integration costs                                                  1                  3                   6                 15
Restructuring costs                                                -                 (2)                  2                  -

Total acquisition-related costs-pre-tax                            1                  1                   8                 15
Income taxes(b)                                                    -                  -                   1                  -
Total acquisition-related costs-net of tax                         1                  1                   7                 15
Certain significant items:
Operational efficiency initiative(c)                               -                 (1)                  -                (18)
Supply network strategy(d)                                         -                  1                   2                  4
Other restructuring charges and
cost-reduction/productivity initiatives(e)                         7                  4                  20                  7
Certain asset impairment charges(f)                                5                  -                  19                  -

Net loss on sale of assets(g)                                      -                  -                   3                  -
Other(h)                                                           -                  5                   -                 11
Total certain significant items-pre-tax                           12                  9                  44                  4
Income taxes(b)                                                    3                  2                  11                  -
Total certain significant items-net of tax                         9                  7                  33                  4

Total purchase accounting adjustments, acquisition-related costs, and certain significant items-net of tax

$        45

$ 45 $ 143 $ 127




(a)   Amortization and depreciation expenses related to Purchase accounting
adjustments with respect to identifiable intangible assets and property, plant
and equipment.
(b)  Income taxes include the tax effect of the associated pre-tax amounts,
calculated by determining the jurisdictional location of the pre-tax amounts and
applying that jurisdiction's applicable tax rate.
  Income taxes in Purchase accounting adjustments also includes a tax benefit
related to a remeasurement of deferred taxes resulting from the integration of
acquired businesses for the nine months ended September 30, 2020, in addition to
a tax benefit related to a remeasurement of deferred taxes as a result of
changes in statutory tax rates, for the nine months ended September 30, 2021 and
2020.

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  Income taxes in Acquisition-related costs also includes a tax charge related
to a remeasurement of deferred taxes resulting from the integration of acquired
businesses for the nine months ended September 30, 2020.
(c)   For the nine months ended September 30, 2020, represents a net gain
resulting from a cash payment received pursuant to an agreement related to the
2016 sale of certain U.S. manufacturing sites.
(d)  Represents product transfer costs related to cost-reduction and
productivity initiatives.
(e) For the three months ended September 30, 2021, primarily represents employee
termination costs associated with the realignment of our international
operations. For the nine months ended September 30, 2021 primarily represents
employee termination costs associated with our international operations and
other costs associated with cost-reduction and productivity initiatives.
For the three and nine months ended September 30, 2020, represents employee
termination costs incurred as a result of the CEO transition.
(f)   For the three months ended September 30, 2021, primarily represents asset
impairment charges related to a dairy product termination. For the nine months
ended September 30, 2021, primarily represents asset impairment charges related
to the consolidation of manufacturing sites in China and a dairy product
termination.
(g)  Represents a net loss related to the sale of certain assets of our poultry
automation business located in the U.S. and Canada.
(h)  For the three and nine months ended September 30, 2020, primarily
represents CEO transition-related costs.
The classification of the above items excluded from adjusted net income are as
follows:
                                                            Three Months Ended                      Nine Months Ended
                                                               September 30,                          September 30,
(MILLIONS OF DOLLARS)                                     2021                2020               2021                2020
Cost of sales:
Purchase accounting adjustments                      $         2          $       2          $        5          $       6

Inventory write-offs                                           1                  -                   2                  -
Consulting fees                                                -                  1                   -                  4

Other                                                          -                  -                   5                  -
  Total Cost of sales                                          3                  3                  12                 10

Selling, general & administrative expenses:
Purchase accounting adjustments                                8                 12                  23                 47

Other                                                          -                  5                   -                 11
  Total Selling, general & administrative
expenses                                                       8                 17                  23                 58

Research & development expenses:
Purchase accounting adjustments                                -                  -                   1                  1
  Total Research & development expenses                        -                  -                   1                  1

Amortization of intangible assets:
Purchase accounting adjustments                               35                 34                 104                101
  Total Amortization of intangible assets                     35                 34                 104                101

Restructuring charges and certain
acquisition-related costs:

Integration costs                                              1                  3                   6                 15
Employee termination costs                                     7                  2                  17                  7
Asset impairments                                              -                  -                  13                  -
Exit costs                                                     1                  -                   3                  -
  Total Restructuring charges and certain
acquisition-related costs                                      9                  5                  39                 22

Other (income)/deductions-net:
Net (gain)/loss on sale of assets                              -                 (1)                  3                (18)

Asset impairments                                              3                  -                   3                  -

  Total Other (income)/deductions-net                          3                 (1)                  6                (18)

Provision for taxes on income                                 13                 13                  42                 47

Total purchase accounting adjustments,
acquisition-related costs, and certain
significant items-net of tax                         $        45          $      45          $      143          $     127



Analysis of the condensed consolidated statements of comprehensive income
Substantially all changes in other comprehensive income for the periods
presented are related to foreign currency translation adjustments. These changes
result from the strengthening or weakening of the U.S. dollar as compared to the
currencies in the countries in which we do business. The gains and losses
associated with these changes are deferred on the balance sheet in Accumulated
other comprehensive loss until realized.

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Analysis of the condensed consolidated balance sheets
September 30, 2021 vs. December 31, 2020
For a discussion about the changes in Cash and cash equivalents, Short-term
borrowings, and Long-term debt, net of discount and issuance costs, see
"Analysis of financial condition, liquidity and capital resources" below.
Accounts Receivable, less allowance for doubtful accounts increased as a result
of higher sales in the period and the timing of customer payments, partially
offset by rebate credits issued to customers.
Inventories increased as a result of the build-up of certain products for
increased demand and new product launches, partially offset by timing of
shipments and higher sales than anticipated for certain products.
Property, plant and equipment, less accumulated depreciation increased primarily
as a result of capital spending, partially offset by depreciation expense.
Identifiable intangible assets, less accumulated amortization decreased
primarily as a result of amortization expense.
Accounts payable decreased as a result of the timing of vendor payments.
Accrued expenses increased as a result of increases in accrued contract rebates,
accrued third-party inventory and other expenses, partially offset by the timing
of payments for accrued interest.
Accrued compensation and related items increased primarily due to the accrual of
2021 annual incentive bonuses and savings plan contributions to eligible
employees, as well as a higher sales incentive bonus accrual, partially offset
by the payment of 2020 annual incentive bonuses and savings plan contributions
to eligible employees.
The net changes in Noncurrent deferred tax assets, Noncurrent deferred tax
liabilities, Income taxes payable and Other taxes payable primarily reflect
adjustments to the accrual for the income tax provision, the timing of income
tax payments, the tax impact of various acquisitions and the impact of the
remeasurement of deferred taxes as a result of changes in tax rates.
Other current liabilities and Other noncurrent liabilities decreased primarily
due to the mark-to-market adjustments of derivative instruments and a decrease
in deferred compensation related to net investment activity.
For an analysis of the changes in Total Equity, see the Condensed Consolidated
Statements of Equity and Notes to Condensed Consolidated Financial Statements-
Note 13. Stockholders' Equity.
Analysis of the condensed consolidated statements of cash flows
                                                                       Nine Months Ended
                                                                         September 30,                                 %
(MILLIONS OF DOLLARS)                                              2021                  2020                     Change
Net cash provided by (used in):
Operating activities                                          $      1,534          $     1,408                     9
Investing activities                                                  (316)                (395)                  (20)
Financing activities                                                (1,548)                 720                        *
Effect of exchange-rate changes on cash and cash
equivalents                                                              -                  (13)                       *

Net (decrease)/increase in cash and cash equivalents $ (330)

$     1,720                        *


*Calculation not meaningful.
Operating activities
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Net cash provided by operating activities was $1,534 million for the nine months
ended September 30, 2021, and $1,408 million for the nine months ended September
30, 2020. The increase in operating cash flows was primarily attributable to
higher cash earnings, partially offset by the timing of receipts and payments in
the ordinary course of business.
Investing activities
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Our net cash used in investing activities was $316 million for the nine months
ended September 30, 2021, compared with net cash used in investing activities of
$395 million for the nine months ended September 30, 2020. The net cash used in
investing activities for 2021 was primarily due to capital expenditures and
acquisitions, partially offset by net proceeds from cross-currency interest rate
swaps. The net cash used in investing activities for 2020 was primarily due to
capital expenditures, acquisitions and net payments for cross-currency interest
rate swaps, partially offset by proceeds from the sale of assets, including a
cash payment received pursuant to an agreement related to the 2016 sale of
certain U.S. manufacturing sites.
Financing activities
Nine months ended September 30, 2021 vs. nine months ended September 30, 2020
Our net cash used in financing activities was $1,548 million for the nine months
ended September 30, 2021, compared with net cash provided by financing
activities of $720 million for the nine months ended September 30, 2020. The net
cash used in financing activities for 2021 was primarily attributable to the
repayment of the $300 million aggregate principal amount of our 2018 floating
rate senior notes due 2021 and the $300 million aggregate principal amount of
our 2018 senior notes due 2021, the purchase of treasury shares, the payment of
dividends and taxes paid on

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withholding shares, partially offset by proceeds in connection with the issuance
of common stock under our equity incentive plan. The net cash provided by
financing activities for 2020 was primarily attributable to the proceeds
received from the issuance of senior notes in May 2020 and net proceeds in
connection with the issuance of common stock under our equity incentive plan,
partially offset by the payment of dividends and the purchase of treasury
shares.
Analysis of financial condition, liquidity and capital resources
While we believe our cash and cash equivalents on hand, our operating cash flows
and our existing financing arrangements will be sufficient to support our future
cash needs, this may be subject to the environment in which we operate. Risks to
our ability to meet future funding requirements include global economic
conditions described in the following paragraph.
Global financial markets may be impacted by macroeconomic, business and
financial volatility. As markets change, we will continue to monitor our
liquidity position, but there can be no assurance that a challenging economic
environment or an economic downturn will not impact our liquidity or our ability
to obtain future financing.
Selected measures of liquidity and capital resources
Certain relevant measures of our liquidity and capital resources follow:
                                                       September 30,       December 31,
(MILLIONS OF DOLLARS)                                       2021               2020
Cash and cash equivalents                             $        3,274      $       3,604
Accounts receivable, net(a)                                    1,152              1,013
Short-term borrowings                                              -                  4
Current portion of long-term debt                                  -        

600


Long-term debt, net of discount and issuance costs             6,592        

6,595


Working capital                                                5,211        

4,441

Ratio of current assets to current liabilities                  4.54:1      

3.05:1




(a)  Accounts receivable are usually collected over a period of 45 to 75 days.
For the nine months ended September 30, 2021, compared with December 31, 2020,
the number of days that accounts receivables are outstanding remained within
this range. We regularly monitor our accounts receivable for collectability,
particularly in markets where economic conditions remain uncertain. We believe
that our allowance for doubtful accounts is appropriate. Our assessment is based
on such factors as past due aging, historical and expected collection patterns,
the financial condition of our customers, the robust nature of our credit and
collection practices and the economic environment.
For additional information about the sources and uses of our funds, see the
Analysis of the condensed consolidated balance sheets and Analysis of the
condensed consolidated statements of cash flows sections of this MD&A.
Credit facility and other lines of credit
In December 2016, we entered into an amended and restated revolving credit
agreement with a syndicate of banks providing for a multi-year $1.0 billion
senior unsecured revolving credit facility (the credit facility). In December
2018, the maturity for the amended and restated credit facility was extended
through December 2023. Subject to certain conditions, we have the right to
increase the credit facility to up to $1.5 billion. The credit facility contains
a financial covenant requiring us to not exceed a maximum total leverage ratio
(the ratio of consolidated net debt as of the end of the period to consolidated
Earnings Before Interest, Income Taxes, Depreciation and Amortization (EBITDA)
for such period) of 3.50:1. Upon entering into a material acquisition, the
maximum total leverage ratio increases to 4.00:1, and extends until the fourth
full consecutive fiscal quarter ended immediately following the consummation of
a material acquisition.
The credit facility also contains a financial covenant requiring that we
maintain a minimum interest coverage ratio (the ratio of EBITDA at the end of
the period to interest expense for such period) of 3.50:1. In addition, the
credit facility contains other customary covenants.
We were in compliance with all financial covenants as of September 30, 2021 and
December 31, 2020. There were no amounts drawn under the credit facility as of
September 30, 2021 or December 31, 2020.
We have additional lines of credit and other credit arrangements with a group of
banks and other financial intermediaries for general corporate purposes. We
maintain cash and cash equivalent balances in excess of our outstanding
short-term borrowings. As of September 30, 2021, we had access to $71 million of
lines of credit which expire at various times through 2021 and are generally
renewed annually. There were no borrowings outstanding related to these
facilities as of September 30, 2021 and $4 million of borrowings outstanding
related to these facilities as of December 31, 2020.
Domestic and international short-term funds
Many of our operations are conducted outside the U.S. The amount of funds held
in the U.S. will fluctuate due to the timing of receipts and payments in the
ordinary course of business and due to other reasons, such as business
development activities. As part of our ongoing liquidity assessments, we
regularly monitor the mix of U.S. and international cash flows (both inflows and
outflows). Actual repatriation of overseas funds can result in additional U.S.
and local income taxes, such as U.S. state income taxes, local withholding
taxes, and taxes on currency gains and losses.
Global economic conditions
Challenging economic conditions in recent years have not had, nor do we
anticipate that it will have, a significant impact on our liquidity. Due to our
operating cash flows, financial assets, access to capital markets and available
lines of credit and revolving credit agreements, we continue to believe that we
have the ability to meet our liquidity needs for the foreseeable future. As
markets change, we continue to monitor our liquidity position. There can be no
assurance that a challenging economic environment or an economic downturn would
not impact our ability to obtain financing in the future.

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Debt
On August 20, 2021, we redeemed, upon maturity, the $300 million aggregate
principal amount of our 2018 floating rate senior notes due 2021 and the $300
million aggregate principal amount of our 2018 senior notes due 2021.
On May 12, 2020, we issued $1.25 billion aggregate principal amount of our
senior notes (2020 senior notes), with an original issue discount of $10
million. These notes are comprised of $750 million aggregate principal amount of
2.000% senior notes due 2030 and $500 million aggregate principal amount of
3.000% senior notes due 2050. On October 13, 2020, the net proceeds were used to
repay the $500 million aggregate principal amount of our 3.450% 2015 senior
notes due 2020 and the remainder will be used for general corporate purposes.
On August 20, 2018, we issued $1.5 billion aggregate principal amount of our
senior notes (2018 senior notes), with an original issue discount of $4 million.
On September 12, 2017, we issued $1.25 billion aggregate principal amount of our
senior notes (2017 senior notes), with an original issue discount of $7 million.
On November 13, 2015, we issued $1.25 billion aggregate principal amount of our
senior notes (2015 senior notes), with an original issue discount of $2 million.
On January 28, 2013, we issued $3.65 billion aggregate principal amount of our
senior notes (2013 senior notes) in a private placement, with an original issue
discount of $10 million.
The 2013, 2015, 2017, 2018 and 2020 senior notes are governed by an indenture
and supplemental indenture (collectively, the indenture) between us and Deutsche
Bank Trust Company Americas, as trustee. The indenture contains certain
covenants, including limitations on our and certain of our subsidiaries' ability
to incur liens or engage in sale lease-back transactions. The indenture also
contains restrictions on our ability to consolidate, merge or sell substantially
all of our assets. In addition, the indenture contains other customary terms,
including certain events of default, upon the occurrence of which, the 2013,
2015, 2017, 2018 and 2020 senior notes may be declared immediately due and
payable.
Pursuant to the indenture, we are able to redeem the 2013, 2015, 2017, 2018 and
2020 senior notes of any series, in whole or in part, at any time by paying a
"make whole" premium, plus accrued and unpaid interest to, but excluding, the
date of redemption. Pursuant to our tax matters agreement with Pfizer, we will
not be permitted to redeem the 2013 senior notes due 2023 pursuant to this
optional redemption provision, except under limited circumstances. Upon the
occurrence of a change of control of us and a downgrade of the 2013, 2015, 2017,
2018 and 2020 senior notes below an investment grade rating by each of Moody's
Investors Service, Inc. and Standard & Poor's Ratings Services, we are, in
certain circumstances, required to make an offer to repurchase all of the
outstanding 2013, 2015, 2017, 2018 and 2020 senior notes at a price equal to
101% of the aggregate principal amount of the 2013, 2015, 2017, 2018 and 2020
senior notes together with accrued and unpaid interest to, but excluding, the
date of repurchase.
The components of our long-term debt follow:
            Description                Principal Amount          Interest Rate                            Terms
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on February 2013 Senior Notes due 2023 $1,350 million

                  3.250%          1, 2023
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on November 2015 Senior Notes due 2025 $750 million

                    4.500%          13, 2025
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on September 2017 Senior Notes due 2027 $750 million

                    3.000%          12, 2027
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on August 2018 Senior Notes due 2028 $500 million

                    3.900%          20, 2028
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on May 15, 2020 Senior Notes due 2030 $750 million

                    2.000%          2030
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on February 2013 Senior Notes due 2043 $1,150 million

                  4.700%          1, 2043
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on September 2017 Senior Notes due 2047 $500 million

                    3.950%          12, 2047
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on August 2018 Senior Notes due 2048 $400 million

                    4.450%          20, 2048
                                                                                    Interest due semi annually, not subject to
                                                                                    amortization, aggregate principal due on May 15,
2020 Senior Notes due 2050          $500 million                    3.000%          2050


Credit Ratings
Two major corporate debt-rating organizations, Moody's and S&P, assign ratings
to our short-term and long-term debt. A security rating is not a recommendation
to buy, sell or hold securities and the rating is subject to revision or
withdrawal at any time by the rating organization. Each rating should be
evaluated independently of any other rating.

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The following table provides the current ratings assigned by these rating
agencies to our commercial paper and senior unsecured non-credit-enhanced
long-term debt:
                             Commercial
                               Paper               Long-term Debt               Date of
Name of Rating Agency          Rating         Rating            Outlook       Last Action
Moody's                         P-2            Baa1             Stable        August 2017
S&P                             A-2            BBB              Stable       December 2016


Share Repurchase Program
In December 2018, the company's Board of Directors authorized a $2.0 billion
share repurchase program. As of September 30, 2021, there was approximately $879
million remaining under this authorization. Purchases of Zoetis shares may be
made at the discretion of management, depending on market conditions and
business needs. Share repurchases may be executed through various means,
including open market or privately negotiated transactions. The company
temporarily suspended share repurchases beginning in the second quarter of 2020.
In January 2021, the company resumed share repurchases under its share
repurchase program. During the first nine months of 2021, approximately 3.1
million shares were repurchased.
Off-balance sheet arrangements
In the ordinary course of business and in connection with the sale of assets and
businesses, we may indemnify our counterparties against certain liabilities that
may arise in connection with a transaction or that are related to activities
prior to a transaction. These indemnifications typically pertain to
environmental, tax, employee and/or product-related matters, and
patent-infringement claims. If the indemnified party were to make a successful
claim pursuant to the terms of the indemnification, we would be required to
reimburse the loss. These indemnifications are generally subject to threshold
amounts, specified claim periods and other restrictions and limitations.
Historically, we have not paid significant amounts under these provisions and,
as of September 30, 2021, or December 31, 2020, recorded amounts for the
estimated fair value of these indemnifications are not significant.
New accounting standards
Recently Issued Accounting Standards Not Adopted as of September 30, 2021
A description of recently issued accounting standards is contained in Note 3.
Accounting Standards of the Notes to Condensed Consolidated Financial
Statements.
Forward-looking statements and factors that may affect future results
This report contains "forward-looking" statements. We generally identify
forward-looking statements by using words such as "anticipate," "estimate,"
"could," "expect," "intend," "project," "plan," "predict," "believe," "seek,"
"continue," "outlook," "objective," "target," "may," "might," "will," "should,"
"can have," "likely" or the negative version of these words or comparable words
or by using future dates in connection with any discussion of future
performance, actions or events.
In particular, forward-looking statements include statements relating to the
impact of the COVID-19 pandemic, our 2021 financial guidance, future actions,
business plans or prospects, prospective products, product approvals or products
under development, product supply disruptions, R&D costs, timing and likelihood
of success, future operating or financial performance, future results of current
and anticipated products and services, strategies, sales efforts, expenses,
production efficiencies, production margins, anticipated timing of generic
market entries, integration of acquired businesses, interest rates, tax rates,
changes in tax regimes and laws, foreign exchange rates, growth in emerging
markets, the outcome of contingencies, such as legal proceedings, plans related
to share repurchases and dividends, government regulation and financial results.
These statements are not guarantees of future performance, actions or events.
Forward-looking statements are subject to risks and uncertainties, many of which
are beyond our control, and are based on assumptions that could prove to be
inaccurate. Among the factors that could cause actual results to differ
materially from past results and future plans and projected future results are
the following:
•the impact of the COVID-19 pandemic on our business, supply chain, customers
and workforce;
•unanticipated safety, quality or efficacy concerns about our products;
•issues with any of our top products;
•failure of our R&D, acquisition and licensing efforts to generate new products
and product lifecycle innovations;
•the possible impact and timing of competing products, including generic
alternatives, on our products and our ability to compete against such products;
•disruptive innovations and advances in medical practices and technologies;
•difficulties and delays in the development or commercialization of new
products;
•consolidation of our customers and distributors;
•changes in the distribution channel for companion animal products;
•failure to successfully acquire businesses, license rights or products,
integrate businesses, form and manage alliances or divest businesses;
•acquiring or implementing new business lines or offering new products and
services;
•restrictions and bans on the use of and consumer preferences regarding
antibacterials in food-producing animals;
•perceived adverse effects linked to the consumption of food derived from
animals that utilize our products or animals generally;
•adverse global economic conditions;
•increased regulation or decreased governmental support relating to the raising,
processing or consumption of food-producing animals;

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•fluctuations in foreign exchange rates and potential currency controls;
•changes in tax laws and regulations;
•legal factors, including product liability claims, antitrust litigation and
governmental investigations, including tax disputes, environmental concerns,
commercial disputes and patent disputes with branded and generic competitors,
any of which could preclude commercialization of products or negatively affect
the profitability of existing products;
•failure to protect our intellectual property rights or to operate our business
without infringing the intellectual property rights of others;
•product launch delays, inventory shortages, recalls or unanticipated costs
caused by manufacturing problems and capacity imbalances;
•an outbreak of infectious disease carried by animals;
•adverse weather conditions and the availability of natural resources;
•the impact of climate change;
•the economic, political, legal and business environment of the foreign
jurisdictions in which we do business;
•a cyber-attack, information security breach or other misappropriation of our
data;
•quarterly fluctuations in demand and costs;
•governmental laws and regulations affecting domestic and foreign operations,
including without limitation, tax obligations and changes affecting the tax
treatment by the U.S. of income earned outside the U.S. that may result from
pending and possible future proposals; and
•governmental laws and regulations affecting our interactions with veterinary
healthcare providers.
However, there may also be other risks that we are unable to predict at this
time. These risks or uncertainties may cause actual results to differ materially
from those contemplated by a forward-looking statement. Such risks and
uncertainties may be amplified by the COVID-19 pandemic and its impact on the
global economy and our business. You should not put undue reliance on
forward-looking statements. Forward-looking statements speak only as of the date
on which they are made. We undertake no obligation to publicly update
forward-looking statements, whether as a result of new information, future
events or otherwise, except as required by law or by the rules and regulations
of the SEC. You are advised, however, to consult any further disclosures we make
on related subjects in our Form 10-Q and 8-K reports and our other filings with
the SEC. You should understand that it is not possible to predict or identify
all such factors. Consequently, you should not consider the above to be a
complete discussion of all potential risks or uncertainties.

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