Overview of our business



Zoetis is a global leader in the animal health industry, focused on the
discovery, development, manufacture and commercialization of medicines,
vaccines, diagnostic products and services, biodevices, genetic tests and
precision animal health technology. For 70 years, we have been innovating ways
to predict, prevent, detect, and treat animal illness, and continue to stand by
those raising and caring for animals worldwide - from livestock farmers to
veterinarians and pet owners.

We manage our operations through two geographic operating segments: the United
States (U.S.) and International. Within each of these operating segments, we
offer a diversified product portfolio for both companion animal and livestock
customers in order to capitalize on local and regional trends and customer
needs. See Notes to Condensed Consolidated Financial Statements - Note 16.
Segment Information.

We directly market our products to veterinarians and livestock producers located
in approximately 45 countries across North America, Europe, Africa, Asia,
Australia and South America, and are a market leader in nearly all of the major
regions in which we operate. Through our efforts to establish an early and
direct presence in many emerging markets, such as Brazil, Chile, China and
Mexico, we believe we are one of the largest animal health medicines and
vaccines businesses as measured by revenue across emerging markets as a whole.
In markets where we do not have a direct commercial presence, we generally
contract with distributors that provide logistics and sales and marketing
support for our products.

We believe our investments in one of the industry's largest sales organizations,
including our extensive network of technical and veterinary operations
specialists, our high-quality manufacturing and reliability of supply, and our
long track record of developing products that meet customer needs, has led to
enduring and valued relationships with our customers. Our research and
development (R&D) efforts enable us to deliver innovative products to address
unmet needs and evolve our product lines so they remain relevant for our
customers.

We have approximately 300 product lines that we sell in over 100 countries for
the prediction, prevention, detection and treatment of diseases and conditions
that affect various companion animal and livestock species. The diversity of our
product portfolio and our global operations provides stability to our overall
business. For instance, in livestock, impacts on our revenue that may result
from disease outbreaks or weather conditions in a particular market or region
are often offset by increased sales in other regions from exports and other
species as consumers shift to other proteins.

A summary of our 2022 performance compared with the comparable 2021 period
follows:
                                                                                                                 % Change
                                                    Three Months Ended                                                  Related to
                                                        March 31,                                       Foreign
(MILLIONS OF DOLLARS)                             2022                2021            Total            Exchange                  Operational(a)
Revenue                                     $    1,986             $  1,871              6                    (3)                             9
Net income attributable to Zoetis                  595                  559              6                    (6)                            12
Adjusted net income(a)                             625                  603              4                    (4)                             8


(a)  Operational growth and adjusted net income are non-GAAP financial measures.
See the Non-GAAP financial measures section of this Management's Discussion and
Analysis of Financial Condition and Results of Operations (MD&A) for more
information.

Our operating environment



For a description of our operating environment, including factors which could
materially affect our business, financial condition, or future results, see "Our
Operating Environment" in the MD&A of our 2021 Annual Report on Form 10-K. Set
forth below are updates to certain of the factors disclosed in our 2021 Form
10-K.

COVID-19 Update

We continue to closely monitor the impact of the coronavirus (COVID-19) pandemic
and the resulting global recession on all aspects of our business across
geographies, including how it has and may continue to impact our customers,
workforce, suppliers and vendors. We cannot predict the impact that the COVID-19
pandemic will have on our customers, vendors and suppliers; however, any
material effect on these parties could adversely impact us. The situation
surrounding COVID-19 remains fluid, and we will continue to actively monitor the
situation and may take actions that alter our business operations that we
determine are in the best interests of our workforce, customers, vendors,
suppliers, and other stakeholders, or as required by federal, state, or local
authorities. For further information regarding the impact of COVID-19 on the
Company, see Item 1A, Risk Factors in this Quarterly Report on Form 10-Q.

Russia's Invasion of Ukraine

Russia's invasion of Ukraine and the global response, including sanctions
imposed by the United States and other countries, have increased global economic
and political uncertainty. As we announced on March 16, 2022, our first concern
remains the safety of our colleagues and their families in Ukraine. We have
remained guided by our purpose to nurture the world and humankind by advancing
care for animals. With this in mind, we continue to support our veterinary and
livestock customers in Russia to address people's fundamental needs for a safe
food supply and animal care. Our operations in Russia will be focused on
maintaining a supply of medicines and vaccines in compliance with any sanctions
that are put in place. We do not directly source input materials or components
from Russia and do not have any manufacturing plants in Russia or Ukraine. While
we do expect sales in the affected regions to be impacted by this situation,
Russia and Ukraine are not among our top 12 international markets and although
we are unable to predict the impact of this crisis on the global economy or on
our results of operations, we do not expect it to have a material adverse effect
to our results or financial condition.

                                                                            

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Global Supply Chain Disruption



We have experienced isolated supply chain challenges for certain products. Some
of these challenges are expected to continue this year, but are being managed by
our global manufacturing network through certain supply chain optimizations,
controlled launches for new products in additional markets and customer
coordination.

Quarterly Variability of Financial Results



Our quarterly financial results are subject to variability related to a number
of factors including, but not limited to: the impact of the COVID-19 pandemic
discussed above, global macroeconomic conditions, including Russia's invasion of
Ukraine and global supply chain disruption discussed above, variability in
distributor inventory stocking levels as a result of expected demand and
promotional activities, weather patterns, herd management decisions, regulatory
actions, inflation, competitive dynamics, disease outbreaks, product and
geographic mix, timing of price increases and timing of investment decisions.

Disease Outbreaks



Sales of our livestock products have in the past been, and may in the future be,
adversely affected by the outbreak of disease carried by animals, such as the
current avian flu outbreak in North America. Outbreaks of disease may reduce
regional or global sales of particular animal-derived food products or result in
reduced exports of such products, either due to heightened export restrictions
or import prohibitions, which may reduce demand for our products. Also, the
outbreak of any highly contagious disease near our main production sites could
require us to immediately halt production of our products at such sites or force
us to incur substantial expenses in procuring raw materials or products
elsewhere. Alternatively, sales of products that treat specific disease
outbreaks may increase.

Foreign Exchange Rates



Significant portions of our revenue and costs are exposed to changes in foreign
exchange rates. Our products are sold in more than 100 countries and, as a
result, our revenue is influenced by changes in foreign exchange rates. For the
three months ended March 31, 2022, approximately 44% of our revenue was
denominated in foreign currencies. We seek to manage our foreign exchange risk,
in part, through operational means, including managing same-currency revenue in
relation to same-currency costs and same-currency assets in relation to
same-currency liabilities. As we operate in multiple foreign currencies,
including the euro, Chinese yuan, Brazilian real, Australian dollar, British
pound, Japanese yen and other currencies, changes in those currencies relative
to the U.S. dollar will impact our revenue, cost of goods and expenses, and
consequently, net income. Exchange rate fluctuations may also have an impact
beyond our reported financial results and directly impact operations. These
fluctuations may affect the ability to buy and sell our goods and services
between markets impacted by significant exchange rate variances. For the three
months ended March 31, 2022, approximately 56% of our total revenue was in U.S.
dollars. Our year-over-year total revenue growth was unfavorably impacted by
approximately 3% from changes in foreign currency values relative to the U.S.
dollar.

Non-GAAP financial measures

We report information in accordance with U.S. generally accepted accounting
principles (GAAP). Management also measures performance using non-GAAP financial
measures that may exclude certain amounts from the most directly comparable GAAP
financial measure. Despite the importance of these measures to management in
goal setting and performance measurement, non-GAAP financial measures have no
standardized meaning prescribed by U.S. GAAP and, therefore, have limits in
their usefulness to investors and may not be comparable to the calculation of
similar measures of other companies. We present certain identified non-GAAP
measures solely to provide investors with useful information to more fully
understand how management assesses performance.

Operational Growth



We believe that it is important to not only understand overall revenue and
earnings growth, but also "operational growth." Operational growth is a non-GAAP
financial measure defined as revenue or earnings growth excluding the impact of
foreign exchange. This measure provides information on the change in revenue and
earnings as if foreign currency exchange rates had not changed between the
current and prior periods to facilitate a period-to-period comparison. We
believe this non-GAAP measure provides a useful comparison to previous periods
for the company and investors, but should not be viewed as a substitute for U.S.
GAAP reported growth.

Adjusted Net Income and Adjusted Earnings Per Share



Adjusted net income and the corresponding adjusted earnings per share (EPS) are
non-GAAP financial measures of performance used by management. We believe these
financial measures are useful supplemental information to investors when
considered together with our U.S. GAAP financial measures. We report adjusted
net income to portray the results of our major operations, and the discovery,
development, manufacture and commercialization of our products, prior to
considering certain income statement elements. We define adjusted net income and
adjusted EPS as net income attributable to Zoetis and EPS before the impact of
purchase accounting adjustments, acquisition-related costs and certain
significant items.

We recognize that, as an internal measure of performance, the adjusted net
income and adjusted EPS measures have limitations, and we do not restrict our
performance management process solely to these metrics. A limitation of the
adjusted net income and adjusted EPS measures is that they provide a view of our
operations without including all events during a period, such as the effects of
an acquisition or amortization of purchased intangibles, and do not provide a
comparable view of our performance to other companies. The adjusted net income
and adjusted EPS measures are not, and should not be viewed as, a substitute for
U.S. GAAP reported net income and reported EPS. See the Adjusted Net Income
section below for more information.

                                                                            

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Analysis of the condensed consolidated statements of income



The following discussion and analysis of our statements of income should be read
along with our condensed consolidated financial statements and the notes thereto
included elsewhere in Part I- Item 1 of this Quarterly Report on Form 10-Q.
                                                                                    Three Months
                                                                                        Ended
                                                                                      March 31,                %
(MILLIONS OF DOLLARS)                                                                      2022              2021             Change
Revenue                                                                                 $  1,986          $  1,871               6
Costs and expenses:
Cost of sales                                                                                569               549               4
% of revenue                                                                                28.7  %           29.3  %
Selling, general and administrative expenses                                                 465               409              14
% of revenue                                                                                  23  %             22  %
Research and development expenses                                                            122               118               3
% of revenue                                                                                   6  %              6  %
Amortization of intangible assets                                                             41                40               3
Restructuring charges and certain acquisition-related costs                                    2                 9             (78)
Interest expense, net of capitalized interest                                                 53                57              (7)
Other (income)/deductions-net                                                                  7                 2                   *
Income before provision for taxes on income                                                  727               687               6
% of revenue                                                                                  37  %             37  %
Provision for taxes on income                                                                133               129               3
Effective tax rate                                                                          18.3  %           18.8  %
Net income before allocation to noncontrolling interests                                     594               558               6
Less: Net loss attributable to noncontrolling interests                                       (1)               (1)                  *
Net income attributable to Zoetis Inc.                                                  $    595          $    559               6
% of revenue                                                                                  30  %             30  %

*Calculation not meaningful

Revenue

Three months ended March 31, 2022 vs. three months ended March 31, 2021



Total revenue increased by $115 million, or 6%, in the three months ended March
31, 2022, compared with the three months ended March 31, 2021, an increase of
$168 million, or 9%, on an operational basis. Operational revenue growth was
comprised primarily of the following:

•volume growth from new products of approximately 5%;

•price growth of approximately 3%; and

•volume growth from in-line products, including key dermatology products, of approximately 1%.

Foreign exchange decreased reported revenue growth by approximately 3%.



Costs and Expenses
Cost of sales
                                           Three Months Ended
                                               March 31,                %
(MILLIONS OF DOLLARS)                                      2022        2021       Change
Cost of sales                                            $ 569       $ 549          4
% of revenue                                              28.7  %     29.3  %

Three months ended March 31, 2022 vs. three months ended March 31, 2021



Cost of sales as a percentage of revenue was 28.7% in the three months ended
March 31, 2022, compared with 29.3% in the three months ended March 31, 2021.
The decrease was primarily as a result of:

•favorable product mix;

•price increases; and

•favorable foreign exchange,

partially offset by:

•unfavorable manufacturing and other costs; and

•higher freight and import costs.

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Selling, general and administrative expenses


                                                                                                          Three Months
                                                                                                              Ended
                                                                                                            March 31,                %
(MILLIONS OF DOLLARS)                                                                                            2022              2021             Change
Selling, general and administrative expenses                                                                  $    465          $    409              14
% of revenue                                                                                                        23  %             22  %

Three months ended March 31, 2022 vs. three months ended March 31, 2021



SG&A expenses increased by $56 million, or 14%, in the three months ended March
31, 2022, compared with the three months ended March 31, 2021, primarily as a
result of:

•an increase in certain compensation-related costs primarily due to additional headcount;

•higher travel and entertainment expenses;

•an increase in investments to support revenue growth;

•higher bad debt reserves for accounts receivables; and

•higher freight and logistics costs,

partially offset by:

•favorable foreign exchange.

Research and development expenses


                                                       Three Months Ended
                                                           March 31,                %
(MILLIONS OF DOLLARS)                                                  2022        2021       Change
Research and development expenses                                    $ 122       $ 118          3
% of revenue                                                             6  %        6  %

Three months ended March 31, 2022 vs. three months ended March 31, 2021



R&D expenses increased by $4 million, or 3%, in the three months ended March 31,
2022, compared with the three months ended March 31, 2021, primarily as a result
of:

•an increase in certain compensation-related costs to support innovation; and

•increased spending driven by project investments,

partially offset by:

•favorable foreign exchange.

Amortization of intangible assets


                                                                                              Three Months Ended
                                                                                                   March 31,                 %
(MILLIONS OF DOLLARS)                                                                                    2022              2021            Change
Amortization of intangible assets                                                                     $     41          $     40              3


Restructuring charges and certain acquisition-related costs


                                                                                                                           Three Months Ended
                                                                                                                               March 31,                  %
(MILLIONS OF DOLLARS)                                                                                                                 2022              2021            Change
Restructuring charges and certain acquisition-related
costs                                                                                                                              $      2          $      9            (78)

Three months ended March 31, 2022 vs. three months ended March 31, 2021



Restructuring charges and certain acquisition-related costs were $2 million and
$9 million in the three months ended March 31, 2022 and 2021, respectively.
Restructuring charges and certain acquisition-related costs in the three months
ended March 31, 2022 primarily consisted of integration costs related to recent
acquisitions. Restructuring charges and certain acquisition-related costs in the
three months ended March 31, 2021 consisted of employee termination and exit
costs associated with cost-reduction and productivity initiatives, integration
costs related to recent acquisitions and restructuring charges related to CEO
transition-related costs.

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Interest expense, net of capitalized interest


                                                                             Three Months Ended
                                                                                  March 31,                 %
(MILLIONS OF DOLLARS)                                                                   2022              2021               Change
Interest expense, net of capitalized interest                                        $     53          $     57              (7)


Three months ended March 31, 2022 vs. three months ended March 31, 2021



Interest expense, net of capitalized interest, decreased by 7% in the three
months ended March 31, 2022, compared with the three months ended March 31,
2021, primarily as a result of the redemption, upon maturity, of the $300
million aggregate principal amount of our 2018 floating rate senior notes and
the $300 million aggregate principal amount of our 2018 senior notes in August
2021.

Other (income)/deductions-net
                                                    Three Months Ended
                                                         March 31,               %
(MILLIONS OF DOLLARS)                                                 2022      2021      Change
Other (income)/deductions-net                                        $  7      $  2             *


*Calculation not meaningful

Three months ended March 31, 2022 vs. three months ended March 31, 2021

The change in Other (income)/deductions-net is primarily as a result of higher foreign currency losses in the current period.

Provision for taxes on income


                                                    Three Months Ended
                                                        March 31,                %
(MILLIONS OF DOLLARS)                                               2022        2021       Change
Provision for taxes on income                                     $ 133       $ 129          3
Effective tax rate                                                 18.3  %     18.8  %

Three months ended March 31, 2022 vs. three months ended March 31, 2021

Our effective tax rate was 18.3% for the three months ended March 31, 2022, compared with 18.8% for the three months ended March 31, 2021. The lower effective tax rate for the three months ended March 31, 2022 was primarily attributable to:

•a $7 million discrete tax benefit recorded in the three months ended March 31, 2022 related to various tax items; and

•a $2 million discrete tax benefit recorded in the three months ended March 31, 2022 related to the effective settlement of certain issues with tax authorities,

partially offset by:



•changes in the jurisdictional mix of earnings, which includes the impact of the
location of earnings from operations and repatriation costs. The jurisdictional
mix of earnings can vary as a result of repatriation decisions, operating
fluctuations in the normal course of business and the impact of non-deductible
items and non-taxable items; and

•$9 million and $13 million discrete tax benefits recorded in the three months
ended March 31, 2022 and 2021, respectively, related to the excess tax benefits
for share-based payments.



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Operating Segment Results



On a global basis, the mix of revenue between companion animal and livestock
products was as follows:

                                                                                                                % Change
                                               Three Months Ended                                                           Related to
                                                   March 31,                                                 Foreign
(MILLIONS OF DOLLARS)                        2022                2021              Total                    Exchange                   Operational
U.S.
Companion animal                       $      774             $    658                 18                          -                             18
Livestock                                     246                  275                (11)                         -                            (11)
                                            1,020                  933                  9                          -                              9
International
Companion animal                              489                  418                 17                         (6)                            23
Livestock                                     459                  504                 (9)                        (6)                            (3)
                                              948                  922                  3                         (5)                             8
Total
Companion animal                            1,263                1,076                 17                         (3)                            20
Livestock                                     705                  779                 (9)                        (3)                            (6)
Contract manufacturing & human
health                                         18                   16                 13                         (4)                            17
                                       $    1,986             $  1,871                  6                         (3)                             9

Earnings by segment and the operational and foreign exchange changes versus the comparable prior year period were as follows:


                                                                                                                            % Change
                                                           Three Months Ended                                                           Related to
                                                                March 31,                                                Foreign
(MILLIONS OF DOLLARS)                                    2022                2021              Total                    Exchange                   Operational
U.S.
Revenue                                             $    1,020           $     933                  9                          -                              9
Cost of Sales                                              185                 184                  1                          -                              1
Gross Profit                                               835                 749                 11                          -                             11
Gross Margin                                              81.9   %            80.3  %
Operating Expenses                                         165                 131                 26                          -                             26
Other (income)/deductions-net                                -                   1                     *                           *                                *
U.S. Earnings                                              670                 617                  9                          -                              9

International
Revenue                                                    948                 922                  3                         (5)                             8
Cost of Sales                                              265                 282                 (6)                        (6)                             -
Gross Profit                                               683                 640                  7                         (5)                            12
Gross Margin                                              72.0   %            69.4  %
Operating Expenses                                         145                 130                 12                         (6)                            18
Other (income)/deductions-net                                -                   -                     *                           *                                *
International Earnings                                     538                 510                  5                         (6)                            11

Total operating segments                                 1,208               1,127                  7                         (3)                            10

Other business activities                                  (98)                (97)                 1
Reconciling Items:
Corporate                                                 (259)               (230)                13
Purchase accounting adjustments                            (40)                (44)                (9)
Acquisition-related costs                                   (2)                 (5)               (60)
Certain significant items                                    -                  (8)                    *
Other unallocated                                          (82)                (56)                46
Total Earnings                                      $      727           $     687                  6


* Calculation not meaningful.

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Three months ended March 31, 2022 vs. three months ended March 31, 2021

U.S. operating segment

U.S. segment revenue increased by $87 million, or 9%, in the three months ended
March 31, 2022, compared with the three months ended March 31, 2021, reflecting
an increase of $116 million in companion animal products, partially offset by a
decrease of $29 million in livestock products.

•Companion animal revenue growth was driven primarily by increased sales of
parasiticides, primarily Simparica Trio®. In-line product growth benefited from
increased sales of our key dermatology portfolio, diagnostics products and
vaccines.

•Livestock revenue declined due to cattle and poultry, partially offset by
growth in swine. Sales of cattle products declined as a result of generic
competition for Draxxin® and unfavorable conditions in beef and dairy markets,
including increased input costs and dry weather conditions. The poultry
portfolio declined due to the expanded use of lower cost alternatives resulting
from reduced disease pressure from smaller flock sizes and generic competition
for Zoamix®, the company's alternative to antibiotics in medicated feed
additives. Sales of swine products grew slightly as a result of favorable market
conditions for producers and increased disease prevalence.

U.S. segment earnings increased by $53 million, or 9%, in the three months ended
March 31, 2022, compared with the three months ended March 31, 2021, primarily
due to revenue and gross margin growth, partially offset by higher operating
expenses.

International operating segment



International segment revenue increased by $26 million, or 3%, in the three
months ended March 31, 2022, compared with the three months ended March 31,
2021. Operational revenue increased by $78 million, or 8%, driven by growth of
approximately $95 million in companion animal products, partially offset by a
decrease of approximately $17 million in livestock products.

•Companion animal operational revenue growth was driven primarily by increased
sales of our key dermatology portfolio, the recent launches of our mAb
therapies, Librela and Solensia, and growth in the Simparica franchise. Growth
across the broader in-line portfolio benefited from increased pet ownership and
standards of care.

•Livestock operational revenue declined due to decreased sales of swine
products, partially offset by increased sales in fish, cattle and poultry
products. Sales of swine products decreased as a result of falling pork prices
due to an increased supply in China and a comparative period when pork prices
were at an all-time high. Growth in our fish portfolio was primarily due to
increased sales of the Alpha Flux® sea lice treatment product and Alpha Ject®
LiVac vaccine for SRS in Chile. Sales of cattle products grew due to favorable
market conditions and price in key markets, including Brazil and Australia, as
well as demand generation efforts in emerging markets such as Turkey and China.
Growth in the sales of poultry products was primarily due to market growth,
demand generation efforts and supply recovery in Australia, Mexico and Brazil.

•Additionally, International segment revenue was unfavorably impacted by foreign
exchange which decreased revenue by approximately $53 million, or 5%, primarily
driven by the euro, Turkish lira, Japanese yen and Australian dollar.

International segment earnings increased by $28 million, or 5%, in the three months ended March 31, 2022, compared with the three months ended March 31, 2021. Operational earnings growth was $54 million, or 11%, primarily due to revenue and gross margin growth, partially offset by higher operating expenses.

Other business activities



Other business activities includes our Client Supply Services contract
manufacturing results, our human health business and expenses associated with
our dedicated veterinary medicine research and development organization,
research alliances, U.S. regulatory affairs and other operations focused on the
development of our products. Other R&D-related costs associated with non-U.S.
market and regulatory activities are generally included in the International
segment.

Three months ended March 31, 2022 vs. three months ended March 31, 2021



Other business activities net loss increased by $1 million in the three months
ended March 31, 2022, compared with the three months ended March 31, 2021,
reflecting an increase in R&D costs due to an increase in certain
compensation-related costs to support innovation and an increase in project
investments, partially offset by higher earnings in our human health business
and favorable foreign exchange.

Reconciling items

Reconciling items include certain costs that are not allocated to our operating segments results, such as costs associated with the following:



•Corporate, which includes certain costs associated with information technology,
facilities, legal, finance, human resources, business development and
communications, among others. These costs also include certain compensation
costs, certain procurement costs, and other miscellaneous operating expenses
that are not charged to our operating segments, as well as interest income and
expense;

•Certain transactions and events such as (i) Purchase accounting adjustments,
which includes expenses associated with the amortization of fair value
adjustments to inventory, intangible assets, and property, plant and equipment;
(ii) Acquisition-related activities, which includes costs for acquisition and
integration; and (iii) Certain significant items, which includes
non-acquisition-related restructuring charges, certain asset impairment charges,
certain legal and commercial settlements, and costs associated with cost
reduction/productivity initiatives; and

•Other unallocated, which includes (i) certain overhead expenses associated with
our global manufacturing operations not charged to our operating segments; (ii)
certain costs associated with finance that specifically support our global
manufacturing operations; (iii) certain supply chain and global logistics costs;
and (iv) certain procurement costs.


                                                                            

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Three months ended March 31, 2022 vs. three months ended March 31, 2021



Corporate expenses increased by $29 million, or 13%, in the three months ended
March 31, 2022, compared with the three months ended March 31, 2021, primarily
due to investments in information technology and unfavorable foreign exchange,
partially offset by lower interest expense.

Other unallocated expenses increased by $26 million, or 46%, in the three months
ended March 31, 2022, compared with the three months ended March 31, 2021,
primarily due to higher freight charges and manufacturing costs, partially
offset by lower inventory obsolescence, scrap and other charges and favorable
foreign exchange.

See Notes to Condensed Consolidated Financial Statements-Note 16. Segment Information for further information.

Adjusted net income

General description of adjusted net income (a non-GAAP financial measure)



Adjusted net income is an alternative view of performance used by management,
and we believe that investors' understanding of our performance is enhanced by
disclosing this performance measure. The adjusted net income measure is an
important internal measurement for us. Additionally, we measure our overall
performance on this basis in conjunction with other performance metrics. The
following are examples of how the adjusted net income measure is utilized:

•senior management receives a monthly analysis of our operating results that is prepared on an adjusted net income basis;

•our annual budgets are prepared on an adjusted net income basis; and

•other goal setting and performance measurements.

Purchase accounting adjustments



Adjusted net income is calculated prior to considering certain significant
purchase accounting impacts that result from business combinations and net asset
acquisitions. These impacts, primarily associated with certain acquisitions,
include amortization related to the increase in fair value of the acquired
finite-lived intangible assets and depreciation related to the increase/decrease
to fair value of the acquired fixed assets. Therefore, the adjusted net income
measure includes the revenue earned upon the sale of the acquired products
without considering the aforementioned significant charges.

While certain purchase accounting adjustments can occur through 20 or more
years, this presentation provides an alternative view of our performance that is
used by management to internally assess business performance. We believe the
elimination of amortization attributable to acquired intangible assets provides
management and investors an alternative view of our business results by
providing a degree of parity to internally developed intangible assets for which
R&D costs previously have been expensed.

A completely accurate comparison of internally developed intangible assets and
acquired intangible assets cannot be achieved through adjusted net income. These
components of adjusted net income are derived solely from the impact of the
items listed above. We have not factored in the impact of any other differences
in experience that might have occurred if we had discovered and developed those
intangible assets on our own, and this approach does not intend to be
representative of the results that would have occurred in those circumstances.
For example, our R&D costs in total, and in the periods presented, may have been
different; our speed to commercialization and resulting revenue, if any, may
have been different; or our costs to manufacture may have been different. In
addition, our marketing efforts may have been received differently by our
customers. As such, in total, there can be no assurance that our adjusted net
income amounts would have been the same as presented had we discovered and
developed the acquired intangible assets.

Acquisition-related costs



Adjusted net income is calculated prior to considering transaction and
integration costs associated with significant business combinations or net asset
acquisitions because these costs are unique to each transaction and represent
costs that were incurred to acquire and integrate certain businesses as a result
of the acquisition decision. We have made no adjustments for the resulting
synergies.

We believe that viewing income prior to considering these charges provides
investors with a useful additional perspective because the significant costs
incurred in a business combination result primarily from the need to eliminate
duplicate assets, activities or employees--a natural result of acquiring a fully
integrated set of activities. For this reason, we believe that the costs
incurred to convert disparate systems, to close duplicative facilities or to
eliminate duplicate positions (for example, in the context of a business
combination) can be viewed differently from those costs incurred in the ordinary
course of business.

The integration costs associated with a business combination may occur over
several years, with the more significant impacts generally ending within three
years of the transaction. Because of the need for certain external approvals for
some actions, the span of time needed to achieve certain restructuring and
integration activities can be lengthy. For example, due to the regulated nature
of the animal health medicines, vaccines and diagnostics business, the closure
of excess facilities can take several years, as all manufacturing changes are
subject to extensive validation and testing and must be approved by the U.S.
Food and Drug Administration and/or other regulatory authorities.

Certain significant items



Adjusted net income is calculated excluding certain significant items. Certain
significant items represent substantive, unusual items that are evaluated on an
individual basis. Such evaluation considers both the quantitative and the
qualitative aspect of their unusual nature. Unusual, in this context, may
represent items that are not part of our ongoing business; items that, either as
a result of their nature or size, we would not expect to occur as part of our
normal business on a regular basis; items that would be nonrecurring; or items
that relate to products that we no longer sell. While not all-inclusive,
examples of items that could be included as certain significant items would be
costs related to a major non-acquisition-related restructuring charge and
associated implementation costs for a program that is specific in nature with a
defined term, such as those related to our non-acquisition-related
cost-reduction and productivity initiatives; amounts related to disposals of
products or facilities that do not qualify as discontinued operations as defined
by U.S. GAAP; certain asset impairments; adjustments related to the resolution
of certain tax positions; significant currency devaluation; the impact of
adopting certain significant, event-driven tax legislation; costs related to our
CEO transition in fiscal 2020; or charges related to legal


                                                                            

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matters. See Notes to Condensed Consolidated Financial Statements- Note 15.
Commitments and Contingencies. Our normal, ongoing defense costs or settlements
of and accruals on legal matters made in the normal course of our business would
not be considered certain significant items.

Reconciliation



A reconciliation of net income, as reported under U.S. GAAP, to adjusted net
income follows:
                                                                      Three Months Ended
                                                                          March 31,                %
(MILLIONS OF DOLLARS)                                                                 2022       2021       Change
GAAP reported net income attributable to Zoetis                                      $ 595      $ 559         6
Purchase accounting adjustments-net of tax                                              30         34       (12)
Acquisition-related costs-net of tax                                                     1          4       (75)
Certain significant items-net of tax                                                    (1)         6             *
Non-GAAP adjusted net income(a)                                                      $ 625      $ 603         4


*Calculation not meaningful.

(a)  The effective tax rate on adjusted pretax income is 18.9% and 19.1% for the
three months ended March 31, 2022 and 2021, respectively. The lower effective
tax rate for the three months ended March 31, 2022, compared with the three
months ended March 31, 2021, was primarily attributable to (i) a $5 million
discrete tax benefit recorded in the three months ended March 31, 2022 related
to various tax items, and (ii) a $2 million discrete tax benefit recorded in the
three months ended March 31, 2022 related to the effective settlement of certain
issues with tax authorities, partially offset by (i) changes in the
jurisdictional mix of earnings, which includes the impact of the location of
earnings, repatriation costs, operating fluctuations in the normal course of
business and the impact of non-deductible and non-taxable items, and (ii) $9
million and $13 million discrete tax benefits recorded in the three months ended
March 31, 2022 and 2021, respectively, related to the excess tax benefits for
share-based payments.

A reconciliation of reported diluted earnings per share (EPS), as reported under U.S. GAAP, to non-GAAP adjusted diluted EPS follows:


                                                                                   Three Months
                                                                                       Ended
                                                                                     March 31,                %
                                                                                          2022              2021             Change
Earnings per share-diluted(a):
GAAP reported EPS attributable to Zoetis -diluted                                      $   1.26          $   1.17               8
Purchase accounting adjustments-net of tax                                                 0.06              0.07             (14)
Acquisition-related costs-net of tax                                                          -              0.01                   *
Certain significant items-net of tax                                                          -              0.01                   *
Non-GAAP adjusted EPS-diluted                                                          $   1.32          $   1.26               5


* Calculation not meaningful.



(a)  Diluted earnings per share was computed using the weighted-average common
shares outstanding during the period plus the common stock equivalents related
to stock options, restricted stock units, performance-vesting restricted stock
units and deferred stock units.

Adjusted net income includes the following charges for each of the periods
presented:
                                                             Three Months Ended
                                                                 March 31,
(MILLIONS OF DOLLARS)                                                         2022      2021
Interest expense, net of capitalized interest                                $ 53      $ 57
Interest income                                                                 2         1
Income taxes                                                                  145       142
Depreciation                                                                   61        56
Amortization                                                                   13         9



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Adjusted net income, as shown above, excludes the following items:

Three Months Ended


                                                                                           March 31,
(MILLIONS OF DOLLARS)                                                                            2022              2021
Purchase accounting adjustments:
Amortization and depreciation                                                                 $     40          $     44

Total purchase accounting adjustments-pre-tax                                                       40                44
Income taxes(a)                                                                                     10                10
Total purchase accounting adjustments-net of tax                                                    30                34
Acquisition-related costs:

Integration costs                                                                                    2                 3
Restructuring costs                                                                                  -                 2

Total acquisition-related costs-pre-tax                                                              2                 5
Income taxes(a)                                                                                      1                 1
Total acquisition-related costs-net of tax                                                           1                 4

Certain significant items:

Other restructuring charges and cost-reduction/productivity initiatives(b)

                                                                                       2                 7
Certain asset impairment charges                                                                     -                 1

Other                                                                                               (2)                -
Total certain significant items-pre-tax                                                              -                 8
Income taxes(a)                                                                                      1                 2
Total certain significant items-net of tax                                                          (1)                6

Total purchase accounting adjustments, acquisition-related costs, and certain significant items-net of tax

$     30          $     44

(a) Income taxes include the tax effect of the associated pre-tax amounts, calculated by determining the jurisdictional location of the pre-tax amounts and applying that jurisdiction's applicable tax rate.



  Income taxes in Purchase accounting adjustments also includes tax benefits
related to a deferred adjustment as a result of a change in tax basis for the
three months ended March 31, 2022 and a remeasurement of deferred taxes as a
result of changes in statutory tax rates for the three months ended March 31,
2022 and 2021.

(b) For the three months ended March 31, 2022, primarily represents product transfer costs.



For the three months ended March 31, 2021, primarily represents product transfer
costs and employee termination costs related to cost-reduction and productivity
initiatives and the CEO transition.



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The classification of the above items excluded from adjusted net income are as
follows:
                                                                                  Three Months Ended
                                                                                       March 31,
(MILLIONS OF DOLLARS)                                                                        2022              2021
Cost of sales:
Purchase accounting adjustments                                                           $      1          $      2

Inventory write-offs                                                                             -                 1

Other                                                                                            3                 3
  Total Cost of sales                                                                            4                 6

Selling, general & administrative expenses:
Purchase accounting adjustments                                                                  7                 8

  Total Selling, general & administrative expenses                                               7                 8

Amortization of intangible assets:
Purchase accounting adjustments                                                                 32                34
  Total Amortization of intangible assets                                                       32                34

Restructuring charges and certain acquisition-related costs:



Integration costs                                                                                2                 3
Employee termination costs                                                                       -                 4

Exit costs                                                                                       -                 2

Total Restructuring charges and certain acquisition-related costs

                      2                 9

Other (income)/deductions-net:



Other                                                                                           (3)                -
  Total Other (income)/deductions-net                                                           (3)                -

Provision for taxes on income                                                                   12                13

Total purchase accounting adjustments, acquisition-related costs, and certain significant items-net of tax

$     30          $     44

Analysis of the condensed consolidated statements of comprehensive income



Changes in other comprehensive income for the periods presented are primarily
related to foreign currency translation adjustments and unrealized
gains/(losses) on derivative instruments. The foreign currency translation
adjustment changes result from the strengthening or weakening of the U.S. dollar
as compared to the currencies in the countries in which we do business.
Unrealized gains/(losses) on the changes in the fair value of derivative
instruments are recorded within Accumulated other comprehensive income/(loss)
and reclassified into earnings depending on the nature and purpose of the
financial instrument, as described in Note 9. Financial Instruments of the Notes
to Condensed Consolidated Financial Statements.

Analysis of the condensed consolidated balance sheets

March 31, 2022 vs. December 31, 2021

For a discussion about the changes in Cash and cash equivalents, Short-term borrowings, and Long-term debt, net of discount and issuance costs, see "Analysis of financial condition, liquidity and capital resources" below.

Accounts Receivable, less allowance for doubtful accounts increased primarily due to higher net sales in the period and timing of customer payments.

Inventories increased primarily as a result of the build-up of certain products for increased demand and new product launches, as well as the timing of shipments.



Other current assets increased primarily due to the mark-to-market adjustment of
derivative instruments, higher prepaid expenses and the reclassification of a
derivative instrument maturing within one year from Other noncurrent assets,
partially offset by the timing of income tax payments.

Other noncurrent assets increased primarily due to a reclassification of collateral received related to derivative contracts to Other current liabilities, partially offset by the reclassification of a derivative instrument maturing within one year to Other current assets.

Accounts payable decreased as a result of the timing of vendor payments.



Accrued expenses decreased primarily as a result of the timing of payments of
customer rebates from the prior period and the timing of payments for accrued
interest.


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Accrued compensation and related items decreased due to the payments of 2021
annual incentive bonuses and savings plan contributions to eligible employees,
as well as payments for sales incentive bonuses, partially offset by the accrual
of 2022 annual incentive bonuses and savings plan contributions to eligible
employees, sales incentive bonus accrual and the timing of the payment of
payroll taxes.

The net changes in Noncurrent deferred tax assets, Noncurrent deferred tax liabilities, Income taxes payable and Other taxes payable primarily reflect adjustments to the accrual for the income tax provision, the timing of income tax payments, the tax impact of various acquisitions and the impact of the remeasurement of deferred taxes as a result of changes in tax rates.

Other current liabilities increased primarily due to a reclassification of collateral received related to derivative contracts from Other noncurrent assets and the mark-to-market adjustment of derivative instruments.



For an analysis of the changes in Total Equity, see the Condensed Consolidated
Statements of Equity and Notes to Condensed Consolidated Financial Statements-
Note 13. Stockholders' Equity.

Analysis of the condensed consolidated statements of cash flows


                                                                     Three Months Ended
                                                                         March 31,                          %
(MILLIONS OF DOLLARS)                                              2022               2021               Change
Net cash provided by (used in):
Operating activities                                          $       309          $    400                   (23)
Investing activities                                                 (118)              (63)                   87
Financing activities                                                 (545)             (339)                   61
Effect of exchange-rate changes on cash and cash
equivalents                                                             4                 -                        *
Net decrease in cash and cash equivalents                     $      (350)         $     (2)                       *


*Calculation not meaningful.

Operating activities

Three months ended March 31, 2022 vs. three months ended March 31, 2021



Net cash provided by operating activities was $309 million for the three months
ended March 31, 2022, and $400 million for the three months ended March 31,
2021. The decrease in operating cash flows was primarily attributable to the
timing of receipts and payments in the ordinary course of business and the
inventory build-up of certain products for increased demand, partially offset by
higher cash earnings.

Investing activities

Three months ended March 31, 2022 vs. three months ended March 31, 2021



Our net cash used in investing activities was $118 million for the three months
ended March 31, 2022, compared with net cash used in investing activities of $63
million for the three months ended March 31, 2021. The net cash used in
investing activities for 2022 was primarily due to capital expenditures. The net
cash used in investing activities for 2021 was primarily due to capital
expenditures and acquisitions, partially offset by net proceeds from
cross-currency interest rate swaps.

Financing activities

Three months ended March 31, 2022 vs. three months ended March 31, 2021



Our net cash used in financing activities was $545 million for the three months
ended March 31, 2022, compared with net cash used in financing activities of
$339 million for the three months ended March 31, 2021. The net cash used in
financing activities for 2022 was primarily attributable to the purchase of
treasury shares, the payment of dividends and taxes paid on withholding shares,
partially offset by proceeds in connection with the issuance of common stock
under our equity incentive plan. The net cash used in financing activities for
2021 was primarily attributable to the purchase of treasury shares, the payment
of dividends and taxes paid on withholding shares, partially offset by proceeds
in connection with the issuance of common stock under our equity incentive plan.

Analysis of financial condition, liquidity and capital resources



While we believe our cash and cash equivalents on hand, our operating cash flows
and our existing financing arrangements will be sufficient to support our cash
needs for the next twelve months and beyond, this may be subject to the
environment in which we operate. Risks to our meeting future funding
requirements include global economic conditions described in the following
paragraph.

Global financial markets may be impacted by macroeconomic, business and
financial volatility. As markets change, we will continue to monitor our
liquidity position. While we do not anticipate it, there can be no assurance
that a challenging economic environment or an economic downturn will not impact
our liquidity or our ability to obtain future financing.

                                                                            

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Selected measures of liquidity and capital resources

Certain relevant measures of our liquidity and capital resources follow:


                                                       March 31,       December 31,
(MILLIONS OF DOLLARS)                                     2022             2021
Cash and cash equivalents                             $    3,135      $       3,485
Accounts receivable, net(a)                                1,222              1,133

Current portion of long-term debt                          1,350            

-


Long-term debt, net of discount and issuance costs         5,228            

6,592


Working capital                                            3,803            

5,133

Ratio of current assets to current liabilities              2.25:1          

3.86:1




(a)  Accounts receivable are usually collected over a period of 45 to 75 days.
For the three months ended March 31, 2022 compared with December 31, 2021, the
number of days that accounts receivables were outstanding remained within this
range. We regularly monitor our accounts receivable for collectability,
particularly in markets where economic conditions remain uncertain. We believe
that our allowance for doubtful accounts is appropriate. Our assessment is based
on such factors as past due aging, historical and expected collection patterns,
the financial condition of our customers, the robust nature of our credit and
collection practices and the economic environment.

For additional information about the sources and uses of our funds, see the Analysis of the condensed consolidated balance sheets and Analysis of the condensed consolidated statements of cash flows sections of this MD&A.

Credit facility and other lines of credit



In December 2016, we entered into an amended and restated revolving credit
agreement with a syndicate of banks providing for a multi-year $1.0 billion
senior unsecured revolving credit facility (the credit facility). In December
2018, the maturity for the amended and restated credit facility was extended
through December 2023. Subject to certain conditions, we have the right to
increase the credit facility to up to $1.5 billion. The credit facility contains
a financial covenant requiring us to not exceed a maximum total leverage ratio
(the ratio of consolidated net debt as of the end of the period to consolidated
Earnings Before Interest, Income Taxes, Depreciation and Amortization (EBITDA)
for such period) of 3.50:1. Upon entering into a material acquisition, the
maximum total leverage ratio increases to 4.00:1, and extends until the fourth
full consecutive fiscal quarter ended immediately following the consummation of
a material acquisition.

The credit facility also contains a financial covenant requiring that we maintain a minimum interest coverage ratio (the ratio of EBITDA at the end of the period to interest expense for such period) of 3.50:1. In addition, the credit facility contains other customary covenants.

We were in compliance with all financial covenants as of March 31, 2022 and December 31, 2021. There were no amounts drawn under the credit facility as of March 31, 2022 or December 31, 2021.



We have additional lines of credit and other credit arrangements with a group of
banks and other financial intermediaries for general corporate purposes. We
maintain cash and cash equivalent balances in excess of our outstanding
short-term borrowings. As of March 31, 2022, we had access to $64 million of
lines of credit which expire at various times through 2022 and are generally
renewed annually. There were no borrowings outstanding related to these
facilities as of March 31, 2022 and December 31, 2021.

Domestic and international short-term funds



Many of our operations are conducted outside the U.S. The amount of funds held
in the U.S. will fluctuate due to the timing of receipts and payments in the
ordinary course of business and due to other reasons, such as business
development activities. As part of our ongoing liquidity assessments, we
regularly monitor the mix of U.S. and international cash flows (both inflows and
outflows). Actual repatriation of overseas funds can result in additional U.S.
and local income taxes, such as U.S. state income taxes, local withholding
taxes, and taxes on currency gains and losses.

Global economic conditions



Challenging economic conditions in recent years have not had, nor do we
anticipate that it will have, a significant impact on our liquidity. Due to our
operating cash flows, financial assets, access to capital markets and available
lines of credit and revolving credit agreements, we continue to believe that we
have the ability to meet our liquidity needs for the foreseeable future. As
markets change, we continue to monitor our liquidity position. There can be no
assurance that a challenging economic environment or an economic downturn would
not impact our ability to obtain financing in the future.

Debt

On August 20, 2021, we redeemed, upon maturity, the $300 million aggregate principal amount of our 2018 floating rate senior notes due 2021 and the $300 million aggregate principal amount of our 2018 senior notes due 2021.



On May 12, 2020, we issued $1.25 billion aggregate principal amount of our
senior notes (2020 senior notes), with an original issue discount of $10
million. These notes are comprised of $750 million aggregate principal amount of
2.000% senior notes due 2030 and $500 million aggregate principal amount of
3.000% senior notes due 2050. On October 13, 2020, the net proceeds were used to
repay the $500 million aggregate principal amount of our 3.450% 2015 senior
notes due 2020 and the remainder is being used for general corporate purposes.
On August 20, 2018, we issued $1.5 billion aggregate principal amount of our
senior notes (2018 senior notes), with an original issue discount of $4 million.
On September 12, 2017, we issued $1.25 billion aggregate principal amount of our
senior notes (2017 senior notes), with an original issue discount of $7 million.
On November 13, 2015, we issued $1.25 billion aggregate principal amount of our
senior notes (2015 senior notes), with an original issue discount of $2 million.
On January 28, 2013, we issued $3.65 billion aggregate principal amount of our
senior notes (2013 senior notes offering) in a private placement, with an
original issue discount of $10 million.

The 2013, 2015, 2017, 2018 and 2020 senior notes are governed by an indenture
and supplemental indenture (collectively, the indenture) between us and Deutsche
Bank Trust Company Americas, as trustee. The indenture contains certain
covenants, including limitations on our and certain of our


                                                                            

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subsidiaries' ability to incur liens or engage in sale lease-back transactions.
The indenture also contains restrictions on our ability to consolidate, merge or
sell substantially all of our assets. In addition, the indenture contains other
customary terms, including certain events of default, upon the occurrence of
which, the 2013, 2015, 2017, 2018 and 2020 senior notes may be declared
immediately due and payable.

Pursuant to the indenture, we are able to redeem the 2013, 2015, 2017, 2018 and
2020 senior notes of any series, in whole or in part, at any time by paying a
"make whole" premium, plus accrued and unpaid interest to, but excluding, the
date of redemption. Pursuant to our tax matters agreement with Pfizer, we will
not be permitted to redeem the 2013 senior notes due 2023 pursuant to this
optional redemption provision, except under limited circumstances. Upon the
occurrence of a change of control of us and a downgrade of the 2013, 2015, 2017,
2018 and 2020 senior notes below an investment grade rating by each of Moody's
Investors Service, Inc. and Standard & Poor's Ratings Services, we are, in
certain circumstances, required to make an offer to repurchase all of the
outstanding 2013, 2015, 2017, 2018 and 2020 senior notes at a price equal to
101% of the aggregate principal amount of the 2013, 2015, 2017, 2018 and 2020
senior notes together with accrued and unpaid interest to, but excluding, the
date of repurchase.

The components of our long-term debt follow:


            Description                Principal Amount          Interest Rate                            Terms
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on February 2013 Senior Notes due 2023 $1,350 million

                  3.250%          1, 2023
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on November 2015 Senior Notes due 2025 $750 million

                    4.500%          13, 2025
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on September 2017 Senior Notes due 2027 $750 million

                    3.000%          12, 2027
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on August 2018 Senior Notes due 2028 $500 million

                    3.900%          20, 2028
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on May 15, 2020 Senior Notes due 2030 $750 million

                    2.000%          2030
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on February 2013 Senior Notes due 2043 $1,150 million

                  4.700%          1, 2043
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on September 2017 Senior Notes due 2047 $500 million

                    3.950%          12, 2047
                                                                                    Interest due semi annually, not subject to
                                                                           

amortization, aggregate principal due on August 2018 Senior Notes due 2048 $400 million

                    4.450%          20, 2048
                                                                                    Interest due semi annually, not subject to
                                                                                    amortization, aggregate principal due on May 15,
2020 Senior Notes due 2050          $500 million                    3.000%          2050


Credit Ratings

Two major corporate debt-rating organizations, Moody's and S&P, assign ratings
to our short-term and long-term debt. A security rating is not a recommendation
to buy, sell or hold securities and the rating is subject to revision or
withdrawal at any time by the rating organization. Each rating should be
evaluated independently of any other rating.

The following table provides the current ratings assigned by these rating
agencies to our commercial paper and senior unsecured non-credit-enhanced
long-term debt:
                             Commercial
                               Paper               Long-term Debt               Date of
Name of Rating Agency          Rating         Rating            Outlook       Last Action
Moody's                         P-2            Baa1             Stable        August 2017
S&P                             A-2            BBB              Stable       December 2016


Share Repurchase Program

In December 2018, the company's Board of Directors authorized a $2.0 billion
share repurchase program. During the first three months of 2022, approximately
1.9 million shares were repurchased for $361 million under this program. As of
March 31, 2022, there was approximately $319 million remaining under this
authorization. In December 2021, the company's Board of Directors authorized an
additional $3.5 billion share repurchase program. Purchases of Zoetis shares may
be made at the discretion of management, depending on market conditions and
business needs. Share repurchases may be executed through various means,
including open market or privately negotiated transactions.

Off-balance sheet arrangements



In the ordinary course of business and in connection with the sale of assets and
businesses, we may indemnify our counterparties against certain liabilities that
may arise in connection with a transaction or that are related to activities
prior to a transaction. These indemnifications typically pertain to
environmental, tax, employee and/or product-related matters, and
patent-infringement claims. If the indemnified party were to make a successful
claim pursuant to the terms of the indemnification, we would be required to
reimburse the loss. These indemnifications are generally subject to threshold
amounts, specified claim periods and other restrictions and limitations.
Historically, we have not paid significant amounts under these provisions and,
as of March 31, 2022 and December 31, 2021, recorded amounts for the estimated
fair value of these indemnifications are not significant.

                                                                            

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New accounting standards

Recently Issued Accounting Standards Not Adopted as of March 31, 2022

A description of recently issued accounting standards is contained in Note 3. Accounting Standards of the Notes to Condensed Consolidated Financial Statements.

Forward-looking statements and factors that may affect future results



This report contains "forward-looking" statements. We generally identify
forward-looking statements by using words such as "anticipate," "estimate,"
"could," "expect," "intend," "project," "plan," "predict," "believe," "seek,"
"continue," "outlook," "objective," "target," "may," "might," "will," "should,"
"can have," "likely" or the negative version of these words or comparable words
or by using future dates in connection with any discussion of future
performance, actions or events.

In particular, forward-looking statements include statements relating to the
impact of the COVID-19 pandemic, our 2022 financial guidance, future actions,
business plans or prospects, prospective products, product approvals or products
under development, product supply disruptions, R&D costs, timing and likelihood
of success, future operating or financial performance, future results of current
and anticipated products and services, strategies, sales efforts, expenses,
production efficiencies, production margins, anticipated timing of generic
market entries, integration of acquired businesses, interest rates, tax rates,
changes in tax regimes and laws, foreign exchange rates, growth in emerging
markets, the outcome of contingencies, such as legal proceedings, plans related
to share repurchases and dividends, government regulation and financial results.
These statements are not guarantees of future performance, actions or events.
Forward-looking statements are subject to risks and uncertainties, many of which
are beyond our control, and are based on assumptions that could prove to be
inaccurate. Among the factors that could cause actual results to differ
materially from past results and future plans and projected future results are
the following:

•the impact of the COVID-19 global pandemic on our business, global supply chain, customers and workforce;

•adverse global economic conditions, including the current crisis in Ukraine and inflation;

•a cyber-attack, information security breach or other misappropriation of our data;

•unanticipated safety, quality or efficacy concerns or issues about our products;

•failure of our R&D, acquisition and licensing efforts to generate new products and product lifecycle innovations;

•the possible impact and timing of competing products, including generic alternatives, on our products and our ability to compete against such products;

•disruptive innovations and advances in medical practices and technologies;

•difficulties or delays in the development or commercialization of new products;

•consolidation of our customers and distributors;

•changes in the distribution channel for companion animal products;

•the economic, political, legal and business environment of the foreign jurisdictions in which we do business;

•failure to successfully acquire businesses, license rights or products, integrate businesses, form and manage alliances or divest businesses;

•restrictions and bans on the use of and consumer preferences regarding antibacterials in food-producing animals;

•perceived adverse effects linked to the consumption of food derived from animals that utilize our products or animals generally;

•increased regulation or decreased governmental support relating to the raising, processing or consumption of food-producing animals;

•fluctuations in foreign exchange rates and potential currency controls;



•legal factors, including product liability claims, antitrust litigation and
governmental investigations, including tax disputes, environmental concerns,
commercial disputes and patent disputes with branded and generic competitors,
any of which could preclude commercialization of products or negatively affect
the profitability of existing products;

•failure to protect our intellectual property rights or to operate our business without infringing the intellectual property rights of others;

•product launch delays, inventory shortages, recalls or unanticipated costs caused by manufacturing problems and capacity imbalances;

•an outbreak of infectious disease carried by animals;

•adverse weather conditions and the availability of natural resources;

•the impact of climate change;

•quarterly fluctuations in demand and costs;



•governmental laws and regulations affecting domestic and foreign operations,
including without limitation, tax obligations and changes affecting the tax
treatment by the U.S. of income earned outside the U.S. that may result from
pending or possible future proposals; and

•governmental laws and regulations affecting our interactions with veterinary healthcare providers.



However, there may also be other risks that we are unable to predict at this
time. These risks or uncertainties may cause actual results to differ materially
from those contemplated by a forward-looking statement. You should not put undue
reliance on forward-looking statements. Forward-looking statements speak only as
of the date on which they are made. We undertake no obligation to publicly
update forward-looking statements, whether as a result of new information,
future events or otherwise, except as required by law or by the rules and
regulations of the SEC. You are advised, however, to consult any further
disclosures we make on related subjects in our Form 10-Q and 8-K reports and our
other filings with the SEC. You should understand that it is not possible to
predict or identify all such factors. Consequently, you should not consider the
above to be a complete discussion of all potential risks or uncertainties.

                                                                            

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