ITEM 7.01 REGULATION FD DISCLOSURE

On October 3, 2022, Zymeworks Inc. ("Zymeworks") issued a press release announcing that management will participate in the following upcoming investor conferences:



     •    Stifel 2022 Healthcare Conference. Zymeworks' management will participate
          in one-on-one meetings and present on November 15th - 16th in New York,
          NY.



     •    Jefferies London Healthcare Conference. Zymeworks' management will
          participate in one-on-one meetings and present on November 15th - 17th in
          London, United Kingdom.

This press release also announced that Zymeworks will present an update on its preclinical research programs at an Early R&D day on October 20th, 2022, in New York, NY.

On October 3, 2022, Zymeworks filed this press release with the Canadian securities regulatory authorities on the System for Electronic Document Analysis and Retrieval at www.sedar.com.

A copy of this press release is attached as Exhibit 99.1 hereto.

The information under this Item 7.01 of this Current Report on Form 8-K and Exhibit 99.1 attached hereto are being furnished and shall not be deemed "filed" for the purposes of Section 18 of the Securities Exchange Act of 1934 (the "Exchange Act"), or otherwise subject to the liability of that section, nor shall such information be deemed incorporated by reference in any filing under the Exchange Act or the Securities Act of 1933, as amended, regardless of the general incorporation language of such filing, except as shall be expressly set forth by specific reference in such filing.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS




(d) Exhibits

Exhibit
  No.     Description

99.1        Press Release dated October 3, 2022.

104       Cover Page Interactive Data File (embedded as Inline XBRL document).

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