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Company	Sector	Price	Change	5-day change	1st Jan %	Capi. (M$)
AVROBIO INC ^USD	Bio Therapeutic Drugs	19.665	19.76%	9.47%	-1.38%	348
BURCON NUTRASCIENCE CORP ^CAD	Biotechnology & Medical Research - ...	1.07	18.89%	26.87%	400.00%	54
PHARMAGREEN BIOTECH INC ^USD	Biotechnology & Medical Research - ...	2.11	17.22%	0.00%	0.00%	158
OXURION ^EUR	Biotechnology & Medical Research - ...	5.29	13.76%	4.85%	28.45%	192
MIRAGEN THERAPEUTICS INC ^USD	Biotechnology & Medical Research - ...	2.4	13.74%	-4.48%	-29.70%	64
CALIX LTD ^AUD	Biotechnology & Medical Research - ...	0.855	12.50%	7.04%	-4.40%	63
NANTKWEST INC ^USD	Bio Therapeutic Drugs	1.2543	11.99%	-0.88%	-3.45%	110
CYNATA THERAPEUTICS LTD ^AUD	Bio Therapeutic Drugs	1.6	11.89%	17.21%	10.00%	91
CURIS, INC. ^USD	Biotechnology & Medical Research - ...	2.69	9.35%	25.70%	226.18%	74
ORGENESIS INC ^USD	Biotechnology & Medical Research - ...	4.64	8.92%	-2.74%	-8.97%	69
MEDLAB CLINICAL LTD ^AUD	Bio Therapeutic Drugs	0.43	8.86%	6.76%	6.76%	58
BIOINVENT INTERNATIONAL AB ^SEK	Bio Therapeutic Drugs	1.712	8.49%	7.49%	-16.81%	84
SPRING BANK PHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	5.1	7.82%	-3.67%	-54.48%	72
OSE IMMUNOTHERAPEUTICS ^EUR	Biotechnology & Medical Research - ...	3.78	7.69%	2.03%	3.24%	60
VIVAKOR INC ^USD	Biotechnology & Medical Research - ...	0.475	7.59%	10.38%	63.52%	116
ENLIVEX THERAPEUTICS LTD ^USD	Bio Therapeutic Drugs	27.84	7.24%	19.36%	319.36%	235
STARPHARMA HOLDINGS LTD (ADR) ^USD	Biotechnology & Medical Research - ...	9.67	6.73%	-19.10%	9.70%	346
QUANTUM GENOMICS ^EUR	Biotechnology & Medical Research - ...	5.55	6.53%	2.96%	-2.43%	97
AVRA MEDICAL ROBOTICS INC ^USD	Biotechnology & Medical Research - ...	2.7	5.88%	5.88%	-9.70%	58
VERASTEM INC ^USD	Bio Therapeutic Drugs	1.54	5.48%	9.77%	-56.55%	115
MELINTA THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	4.4	5.26%	-33.44%	427.31%	52
UNUM THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	2.39	4.82%	-8.06%	-48.18%	71
ORAMED PHARMACEUTICALS, INC. ^USD	Biotechnology & Medical Research - ...	3.5101	4.78%	2.76%	11.67%	57
BRAINSWAY LTD ^ILa	Bio Medical Devices	2066	4.71%	0.00%	0.00%	115
PIERIS PHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	4.47	4.68%	-5.95%	60.53%	218
GNI GROUP LTD ^JPY	Biotechnology & Medical Research - ...	4185	4.63%	8.98%	41.34%	513
CHROMADEX CORP ^USD	Biotechnology & Medical Research - ...	4.7	4.44%	0.67%	31.20%	246
VIKING THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	8.6	4.37%	-0.36%	7.71%	587
ARCH BIOPARTNERS INC ^CAD	Biotechnology & Medical Research - ...	1.21	4.31%	-0.85%	-11.45%	52
PHARNEXT ^EUR	Bio Therapeutic Drugs	12.3	4.24%	-2.07%	12.38%	194
IVERIC BIO INC ^USD	Biotechnology & Medical Research - ...	1.24	4.20%	-4.03%	-0.83%	52
MESOBLAST LIMITED ^AUD	Biotechnology & Medical Research - ...	1.51	4.14%	-6.45%	25.00%	527
CHECKPOINT THERAPEUTICS INC ^USD	Biotechnology & Medical Research - ...	2.81	4.07%	-13.18%	48.35%	112
MEDIGENE AG ^EUR	Biotechnology & Medical Research - ...	6.97	4.03%	-7.71%	-9.21%	179
SERES THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	2.895	3.76%	-6.06%	-38.27%	209
NYMOX PHARMACEUTICAL CORP ^USD	Biotechnology & Medical Research - ...	1.68	3.70%	21.53%	33.59%	118
ACORDA THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	6.795	3.58%	-10.05%	-57.51%	337
EVOLUS INC ^USD	Bio Therapeutic Drugs	16.56	3.56%	6.60%	34.37%	430
XERIS PHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	12.39	3.51%	-0.42%	0.00%	342
FORMYCON AG ^EUR	Biotechnology & Medical Research - ...	31	3.33%	-2.28%	15.38%	314
BIOTON SA ^PLN	Bio Therapeutic Drugs	4.7	3.30%	11.77%	-8.74%	100
SESEN BIO INC ^USD	Bio Therapeutic Drugs	1.26	3.28%	-5.43%	-14.08%	123
AXOVANT GENE THERAPIES LTD ^USD	Bio Therapeutic Drugs	7.6	3.26%	17.95%	638.96%	167
MOLECULAR TEMPLATES INC ^USD	Bio Therapeutic Drugs	7.4	3.21%	-3.76%	77.48%	269
MANNKIND CORPORATION ^USD	Bio Therapeutic Drugs	1.125	3.21%	-4.39%	2.83%	203
MERUS NV ^USD	Bio Therapeutic Drugs	16.25	3.17%	8.02%	12.50%	357
STARPHARMA HOLDINGS LIMITED ^AUD	Biotechnology & Medical Research - ...	1.38	2.99%	-3.60%	13.08%	346
ORGANOVO HOLDINGS INC ^USD	Biotechnology & Medical Research - ...	0.5148	2.96%	3.09%	-47.76%	70
APTOSE BIOSCIENCES INC ^CAD	Biotechnology & Medical Research - ...	3.85	2.94%	-3.86%	43.85%	153
ARGEN-X ^EUR	Bio Therapeutic Drugs	131.4	2.90%	2.00%	49.88%	5 242

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