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Company	Sector	Price	Change	5-day change	1st Jan %	Capi. (M$)
G1 THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	24.61	24.61%	6.13%	3.13%	747
SIRONA BIOCHEM CORP ^CAD	Biotechnology & Medical Research - ...	0.56	16.67%	-18.64%	464.71%	80
OVID THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	1.91	13.02%	2.42%	-30.17%	65
INTREXON CORP ^USD	Biotechnology & Medical Research - ...	8.38	10.26%	36.94%	16.21%	830
DURECT CORPORATION ^USD	Bio Therapeutic Drugs	0.5649	10.20%	-3.94%	6.11%	93
SYNCORE ^TWD	Bio Therapeutic Drugs	29.7	10.00%	10.82%	20.49%	67
CYMABAY THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	7.19	9.60%	-40.85%	-16.65%	822
OBSEVA SA ^USD	Bio Therapeutic Drugs	11	9.45%	-11.30%	-20.62%	558
CYTODYN INC ^USD	Bio Therapeutic Drugs	0.525	9.40%	11.95%	-6.38%	127
SERES THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	2.68	9.39%	-22.71%	-45.80%	149
AUTOLUS THERAPEUTICS LTD - ADR ^USD	Bio Therapeutic Drugs	17.34	9.33%	2.12%	-51.71%	915
PRECISION BIOSCIENCES INC ^USD	Biotechnology & Medical Research - ...	13.65	8.85%	-3.02%	0.00%	676
GERON CORPORATION ^USD	Bio Therapeutic Drugs	1.6	8.84%	5.67%	49.00%	265
PHASEBIO PHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	13.3	8.39%	11.44%	297.09%	306
Y-MABS THERAPEUTICS, INC ^USD	Bio Therapeutic Drugs	22.48	8.18%	-8.58%	2.16%	697
VALENS GROWORKS CORP ^CAD	Biotechnology & Medical Research - ...	3.73	8.12%	-14.00%	127.81%	318
VERMILLION, INC. ^USD	Bio Diagnostics & Testing	1.027	8.11%	-21.49%	216.67%	72
IRONWOOD PHARMACEUTICALS, INC. ^USD	Biotechnology & Medical Research - ...	11.5	8.08%	-4.74%	2.70%	1 777
BIOTIME, INC. ^USD	Bio Therapeutic Drugs	1.11	7.77%	4.00%	13.91%	148
VBI VACCINES INC ^USD	Biotechnology & Medical Research - ...	0.6992	7.57%	-62.86%	-59.38%	173
CATABASIS PHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	6.46	6.78%	1.68%	38.44%	77
SUTRO BIOPHARMA INC ^USD	Bio Therapeutic Drugs	11.81	6.21%	-7.26%	23.28%	262
ALLENA PHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	4.98	6.18%	8.31%	-13.95%	84
ACCELERON PHARMA INC ^USD	Bio Therapeutic Drugs	40.68	6.05%	0.81%	-11.92%	2 091
ZIOPHARM ONCOLOGY INC. ^USD	Bio Therapeutic Drugs	6.0661	6.05%	36.19%	205.88%	679
ZOSANO PHARMA CORP ^USD	Bio Therapeutic Drugs	2.9795	6.03%	-2.09%	32.55%	52
TYME TECHNOLOGIES INC ^USD	Bio Therapeutic Drugs	1.1	5.77%	-8.77%	-71.82%	117
PROGENICS PHARMACEUTICALS, INC. ^USD	Bio Therapeutic Drugs	4.615	5.61%	3.55%	4.05%	347
HOMOLOGY MEDICINES INC ^USD	Bio Therapeutic Drugs	20.2	5.59%	-0.31%	-14.45%	858
CEL-SCI CORPORATION ^USD	Bio Therapeutic Drugs	6.46	5.56%	6.99%	113.24%	127
PTC THERAPEUTICS, INC. ^USD	Bio Therapeutic Drugs	42.61	5.55%	-1.63%	17.63%	2 334
AXSOME THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	24.45	5.52%	8.02%	721.63%	771
BELLICUM PHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	2.025	5.47%	-7.69%	-34.25%	90
POLYNOVO LTD ^AUD	Biotechnology & Medical Research - ...	1.27	5.39%	-4.74%	102.52%	575
TOCAGEN INC ^USD	Bio Therapeutic Drugs	6.1	5.35%	11.99%	-29.48%	108
TCR2 THERAPEUTICS INC ^USD	Biotechnology & Medical Research - ...	15.38	5.27%	-10.91%	0.00%	359
GLOBAL BLOOD THERAPEUTICS INC ^USD	Biotechnology & Medical Research - ...	57.06	5.20%	-5.24%	32.13%	3 298
XENCOR INC ^USD	Bio Therapeutic Drugs	34.23	5.16%	5.00%	-9.98%	1 767
STEALTH BIOTHERAPEUTICS CORP ^USD	Biotechnology & Medical Research - ...	12.89	5.14%	5.06%	0.00%	420
EIGER BIOPHARMACEUTICALS INC ^USD	Biotechnology & Medical Research - ...	11.015	5.00%	3.35%	3.25%	257
MERSANA THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	4.115	4.97%	-8.20%	-3.92%	190
NEKTAR THERAPEUTICS ^USD	Biotechnology & Medical Research - ...	35.3562	4.91%	1.72%	2.53%	5 937
AXOVANT GENE THERAPIES LTD ^USD	Bio Therapeutic Drugs	5.79	4.89%	37.31%	454.22%	155
MEI PHARMA INC ^USD	Bio Therapeutic Drugs	2.6	4.84%	-1.59%	-6.06%	203
NANTKWEST INC ^USD	Bio Therapeutic Drugs	1.09	4.81%	4.10%	-10.34%	127
IVERIC BIO INC ^USD	Biotechnology & Medical Research - ...	1.31	4.80%	-5.79%	4.17%	60
BBI LIFE SCIENCES CORP ^HKD	Biotechnology & Medical Research - ...	2.19	4.78%	0.46%	-4.78%	154
RIGEL PHARMACEUTICALS, INC. ^USD	Bio Therapeutic Drugs	2.335	4.71%	7.73%	-3.04%	358
EPIZYME INC ^USD	Bio Therapeutic Drugs	13	4.67%	-13.07%	101.95%	1 262
VOYAGER THERAPEUTICS INC ^USD	Biotechnology & Medical Research - ...	28	4.67%	13.78%	184.57%	762

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