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Company	Sector	Price	Change	5-day change	1st Jan %	Capi. (M$)
ANGES INC ^JPY	Bio Therapeutic Drugs	408	24.01%	14.93%	-33.87%	260
IDERA PHARMACEUTICALS INC ^USD	Biotechnology & Medical Research - ...	8.51	15.16%	48.78%	-49.59%	170
XOMA CORP ^USD	Bio Therapeutic Drugs	18.55	14.58%	-24.13%	-47.89%	154
ONCOSIL MEDICAL LTD ^AUD	Biotechnology & Medical Research - ...	0.185	12.12%	-9.76%	19.35%	75
OSIRIS THERAPEUTICS, INC. ^USD	Bio Therapeutic Drugs	0.75	10.29%	-92.24%	-87.50%	307
ONCOCYTE CORP ^USD	Bio Therapeutic Drugs	2.85	9.62%	21.28%	-38.71%	102
ONCOSEC MEDICAL INC ^USD	Biotechnology & Medical Research - ...	1.58	8.97%	19.70%	-2.77%	79
VBI VACCINES INC ^USD	Biotechnology & Medical Research - ...	1.98	8.79%	-6.19%	-57.38%	123
GENOCEA BIOSCIENCES INC ^USD	Biotechnology & Medical Research - ...	0.6197	8.72%	-1.88%	-46.58%	51
MENLO THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	8.81	8.63%	11.52%	0.00%	182
CHROMADEX CORP ^USD	Biotechnology & Medical Research - ...	4.8	8.35%	2.78%	-18.37%	248
OVID THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	6.55	8.09%	15.52%	-33.64%	152
OMEROS CORPORATION ^USD	Bio Therapeutic Drugs	20.62	7.51%	-6.10%	6.12%	861
MOLECULAR TEMPLATES INC ^USD	Bio Therapeutic Drugs	5.21	6.98%	3.17%	-48.00%	145
TAPIMMUNE INC ^USD	Biotechnology & Medical Research - ...	8.21	6.49%	8.60%	109.44%	82
NANOCARRIER CO., LTD. ^JPY	Bio Therapeutic Drugs	510	6.47%	3.24%	-21.54%	199
IOVANCE BIOTHERAPEUTICS INC ^USD	Bio Diagnostics & Testing	15.95	6.33%	8.50%	99.38%	1 313
LINICAL CO., LTD. ^JPY	Biotechnology & Medical Research - ...	2476	6.17%	0.41%	52.84%	520
VELOXIS PHARMACEUTICALS A/S ^DKK	Biotechnology & Medical Research - ...	1.11	6.12%	7.35%	29.07%	277
VERSARTIS INC ^USD	Bio Therapeutic Drugs	1.75	6.06%	-1.41%	-20.45%	62
INNOVATE BIOPHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	4.95	6.00%	9.03%	-18.85%	140
ARQULE, INC. ^USD	Biotechnology & Medical Research - ...	6.02	5.99%	9.65%	264.85%	594
BRIGHTPATH BIOTHERAPEUTICS CO LT.. ^JPY	Biotechnology & Medical Research - ...	258	5.74%	-4.80%	-60.97%	92
GNI GROUP LTD ^JPY	Biotechnology & Medical Research - ...	3270	5.65%	0.46%	443.19%	377
MAGFORCE AG ^EUR	Biotechnology & Medical Research - ...	5.62	5.64%	12.40%	-14.75%	153
RIBOMIC INC ^JPY	Bio Therapeutic Drugs	441	5.50%	-2.00%	-26.25%	54
EIDOS THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	18.12	5.41%	19.37%	0.00%	595
LEAP THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	7.26	4.91%	11.35%	16.35%	107
APTEVO THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	5.27	4.77%	16.85%	24.29%	109
EIGER BIOPHARMACEUTICALS INC ^USD	Biotechnology & Medical Research - ...	10.05	4.69%	1.52%	-27.96%	132
MADRIGAL PHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	236.88	4.62%	-3.52%	158.07%	3 593
INFINITY PHARMACEUTICALS INC. ^USD	Biotechnology & Medical Research - ...	2.07	4.55%	10.70%	1.97%	118
INFLARX NV ^USD	Bio Therapeutic Drugs	31.38	4.53%	-2.27%	49.79%	786
PALATIN TECHNOLOGIES, INC. ^USD	Biotechnology & Medical Research - ...	0.9554	4.52%	5.19%	11.24%	184
ERIS LIFESCIENCES LTD ^INR	Bio Therapeutic Drugs	712.05	4.41%	-3.20%	-12.42%	1 363
RETROPHIN INC ^USD	Bio Therapeutic Drugs	26.86	4.35%	-0.85%	27.48%	1 048
VIKING THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	10.69	4.29%	1.14%	163.30%	605
CYTODYN INC ^USD	Bio Therapeutic Drugs	0.49	4.28%	-2.00%	-11.01%	103
MOTIF BIO PLC ^GBp	Bio Therapeutic Drugs	34.2	4.27%	13.62%	-16.59%	121
PARATEK PHARMACEUTICALS INC ^USD	Bio Therapeutic Drugs	10.05	4.15%	-7.80%	-43.85%	317
PTC THERAPEUTICS, INC. ^USD	Bio Therapeutic Drugs	44.89	4.06%	17.24%	169.12%	2 027
CARNA BIOSCIENCES, INC. ^JPY	Biotechnology & Medical Research - ...	1445	4.03%	4.41%	29.02%	121
NEON THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	11.95	4.00%	-1.16%	0.00%	343
PHARMA FOODS INTERNATIONAL CO., .. ^JPY	Biotechnology & Medical Research - ...	442	4.00%	-3.28%	13.62%	111
CHAMPIONS ONCOLOGY INC ^USD	Biotechnology & Medical Research - ...	7.79	3.87%	-2.63%	100.77%	84
CELLDEX THERAPEUTICS, INC. ^USD	Biotechnology & Medical Research - ...	0.4322	3.84%	-4.80%	-84.78%	61
KEZAR LIFE SCIENCES INC ^USD	Bio Therapeutic Drugs	16.7	3.66%	4.44%	0.00%	300
D.WESTERN THERAPEUTICS INSTITUTE.. ^JPY	Bio Therapeutic Drugs	431	3.61%	-1.15%	-15.49%	99
CIDARA THERAPEUTICS INC ^USD	Bio Therapeutic Drugs	4.4	3.53%	18.92%	-35.29%	126
EVOTEC AG ^EUR	Biotechnology & Medical Research - ...	20.6	3.52%	14.29%	52.59%	3 231

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