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Company	Sector	Price	Change	5-day change	1st Jan %	Capi. (M$)
OMEROS CORPORATION ^USD	Biopharmaceuticals	4.64	68.73%	77.78%	-27.84%	291
HEALIXA INC. ^USD	Other Pharmaceuticals	0.7645	35.31%	-33.53%	-16.31%	578
HYUNDAI PHARMACEUTICAL CO., LTD. ^KRW	Generic Pharmaceuticals	5730	25.80%	20.38%	-3.70%	122
ENDO INTERNATIONAL PLC ^USD	Other Pharmaceuticals	0.5701	22.42%	55.04%	-84.84%	134
WOCKHARDT BIO AG ^CHF	Generic Pharmaceuticals	1.58	17.04%	0.00%	20.61%	85
VERRICA PHARMACEUTICALS INC. ^USD	Other Pharmaceuticals	2.17	13.02%	2.84%	-76.31%	86
AERIE PHARMACEUTICALS, INC. ^USD	Other Pharmaceuticals	8.36	11.47%	10.58%	19.09%	406
ZAI LAB LIMITED ^USD	Biopharmaceuticals	38.54	11.13%	12.62%	-38.68%	3 772
HUTCHMED (CHINA) LIMITED ^GBX	Other Pharmaceuticals	220.75	10.38%	3.88%	-58.35%	2 274
BIOMED-LUBLIN WYTWÓRNIA SUROWIC .. ^PLN	Biopharmaceuticals	3.64	10.30%	14.83%	-18.02%	53
MEDICAL DEVELOPMENTS INTERNATION.. ^AUD	Other Pharmaceuticals	1.61	10.27%	4.55%	-67.80%	78
SHAANXI KANGHUI PHARMACEUTICAL C.. ^CNY	Other Pharmaceuticals	22.17	9.75%	9.81%	1.84%	330
NEXT SCIENCE LIMITED ^AUD	Other Pharmaceuticals	0.79	9.72%	1.28%	-36.55%	115
NOVARTIS INDIA LIMITED ^INR	Other Pharmaceuticals	671.3	9.57%	8.58%	-13.41%	210
UNI-BIO SCIENCE GROUP LIMITED ^HKD	Biopharmaceuticals	0.082	9.33%	34.43%	-2.38%	67
BRIDGEBIO PHARMA, INC. ^USD	Other Pharmaceuticals	9.92	9.25%	7.36%	-40.53%	1 465
SIGA TECHNOLOGIES, INC. ^USD	Other Pharmaceuticals	12.61	8.89%	-11.60%	53.99%	913
SYNBIOTIC SE ^EUR	Recreational Pharmaceuticals	15.6	8.18%	-11.26%	-46.58%	52
CHEMOCENTRYX, INC. ^USD	Biopharmaceuticals	26.76	7.99%	2.33%	-26.50%	1 905
COEPTIS THERAPEUTICS, INC. ^USD	Other Pharmaceuticals	3.02	7.86%	2.37%	-25.43%	117
SANOFI-AVENTIS PAKISTAN LIMITED ^PKR	Other Pharmaceuticals	1148.48	7.50%	33.54%	27.94%	54
THERAVANCE BIOPHARMA, INC. ^USD	Other Pharmaceuticals	9.73	7.40%	8.23%	-11.95%	741
INCANNEX HEALTHCARE LIMITED ^AUD	Alternative Medicine	0.225	7.14%	-16.67%	-64.00%	196
AUXLY CANNABIS GROUP INC. ^CAD	Alternative Medicine	0.075	7.14%	-21.05%	-59.46%	52
CORCEPT THERAPEUTICS INCORPORATE.. ^USD	Other Pharmaceuticals	25.44	6.98%	6.89%	28.48%	2 703
ASSERTIO HOLDINGS, INC. ^USD	Other Pharmaceuticals	3.15	6.78%	7.08%	35.32%	143
ANHUI HUANGSHAN CAPSULE CO., LTD.. ^CNY	Other Pharmaceuticals	7.72	6.78%	4.61%	-10.38%	345
HARMONY BIOSCIENCES HOLDINGS, IN.. ^USD	Other Pharmaceuticals	52	6.62%	0.64%	21.95%	3 071
VECTIVBIO HOLDING AG ^USD	Other Pharmaceuticals	5.75	6.48%	3.23%	17.11%	260
AVIDITY BIOSCIENCES, INC. ^USD	Biopharmaceuticals	15.46	6.40%	8.72%	-34.96%	769
ANI PHARMACEUTICALS, INC. ^USD	Other Pharmaceuticals	31.535	6.29%	9.08%	-31.56%	512
ICANIC BRANDS COMPANY INC. ^CAD	Recreational Pharmaceuticals	0.085	6.25%	13.33%	-59.52%	67
PCAS ^EUR	Other Pharmaceuticals	8.2	6.22%	-5.96%	-2.38%	117
DBV TECHNOLOGIES ^EUR	Specialty & Advanced Pharmaceutical...	4.48	6.21%	0.09%	46.45%	437
TWIST BIOSCIENCE CORPORATION ^USD	Biopharmaceuticals	37.08	6.06%	-9.67%	-52.09%	2 086
SINO BIOPHARMACEUTICAL LIMITED ^HKD	Other Pharmaceuticals	4.97	5.97%	10.44%	-8.97%	11 828
CELON PHARMA S.A. ^PLN	Other Pharmaceuticals	15.56	5.85%	1.43%	-53.06%	176
GREENWICH LIFESCIENCES, INC. ^USD	Biopharmaceuticals	8.96	5.79%	5.66%	-63.17%	116
PHARMGEN SCIENCE, INC. ^KRW	Generic Pharmaceuticals	7200	5.73%	11.46%	-31.43%	85
AMNEAL PHARMACEUTICALS, INC. ^USD	Other Pharmaceuticals	3.36	5.66%	5.00%	-29.85%	507
CHINA RESOURCES DOUBLE-CRANE PHA.. ^CNY	Other Pharmaceuticals	27.09	5.57%	19.50%	102.62%	4 217
ZHEJIANG MEDICINE CO., LTD. ^CNY	Other Pharmaceuticals	14.4	5.49%	6.04%	-15.69%	2 059
PURAPHARM CORPORATION LIMITED ^HKD	Alternative Medicine	1.54	5.48%	7.69%	90.12%	78
PETIQ, INC. ^USD	Veterinary Drugs	17.71	5.48%	5.54%	-22.02%	518
GULF PHARMACEUTICAL INDUSTRIES P.. ^AED	Specialty & Advanced Pharmaceutical...	1.36	5.43%	5.43%	-26.09%	428
AVADEL PHARMACEUTICALS PLC ^USD	Other Pharmaceuticals	2.57	5.33%	11.26%	-68.19%	152
WUHAN HITECK BIOLOGICAL PHARMA C.. ^CNY	Other Pharmaceuticals	42.03	5.29%	8.94%	-29.43%	766
PRECIGEN, INC. ^USD	Other Pharmaceuticals	1.41	5.22%	0.71%	-61.99%	293
JERUSALEM PHARMACEUTICALS CO. LT.. ^USD	Generic Pharmaceuticals	3.23	5.21%	0.94%	14.13%	58
FUREN GROUP PHARMACEUTICAL CO., .. ^CNY	Other Pharmaceuticals	2.03	5.18%	-7.31%	-42.98%	190

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