Item 1.01 Entry into a Material Definitive Agreement.






Private Placement Financing


On March 15, 2021, the Company entered into Purchase Agreements, pursuant to which it agreed to sell and issue approximately $45.5. million of its ADSs in the Private Placement. At the closing of the Private Placement, the Company sold and issued to the purchasers 41,915,433 ADSs and 4,191,543 accompanying warrants at a purchase price of $1.08443 (pre-reverse split that took effect immediately prior to the closing of the Merger). The warrants have an exercise price of $1.08443 (pre-reverse split that took effect immediately prior to the closing of the Merger), will expire five years from the date of issuance, and if exercised in full will generate additional proceeds to the Company of approximately $4.5 million.

The Private Placement is exempt from the registration requirements of the Securities Act of 1933, as amended (the "Securities Act"), pursuant to the exemption for transactions by an issuer not involving any public offering under Section 4(a)(2) of the Securities Act and/or Rule 506 of Regulation D of the Securities Act and in reliance on similar exemptions under applicable state laws. Each of the Purchasers represented that it is an accredited investor within the meaning of Rule 501 of Regulation D and is acquiring the securities for its own account for investment and not with a view towards distribution. The Purchase Agreements provide the purchasers with certain registration rights that require the Company to file a Registration Statement with the Securities and Exchange Commission (the "SEC") within 30 days after the closing of the Private Placement for the purposes of registering the resale of the shares issued in the Private Placement.

The preceding summary does not purport to be complete and are qualified in their entirety by reference to the form Purchase Agreement, the Warrant to Purchase American Depositary Shares and the Anti-Dilution Warrant, which are filed as Exhibits 10.1, 10.2 and 10.3, respectively, to this Current Report on Form 8-K, and which are incorporated herein by reference.

The Purchase Agreement filed as an Exhibit to this Form 8-K has been included to provide investors and shareholders with information regarding its terms. It is not intended to provide any other factual information about the Company or the parties thereto. The Purchase Agreement contains representations and warranties that the parties thereto made to, and solely for the benefit of, each other. The assertions embodied in such representations and warranties are qualified by information contained in the confidential disclosure schedules that each may have delivered to the other party in connection with signing the Purchase Agreement. Accordingly, investors and shareholders should not rely on such representations and warranties as characterizations of the actual state of facts . . .

Item 2.01 Completion of Acquisition or Disposition of Assets






Completion of the Merger


On March 16, 2021, Anchiano completed the Merger pursuant to the Merger Agreement. In connection with the Merger, and following the effective time of the Merger (the "Effective Time"), the Company effected a reverse share split of the Company's ordinary shares at a ratio of 4:1 (the "Reverse Split") and increased the number of ordinary shares per ADS from 5 to 20. Following the Reverse Split and closing of the Merger there are approximately 10,697,975 issued and outstanding ADSs of the Company outstanding, with pre-merger Chemomab shareholders owning approximately 90% and pre-merger Anchiano shareholders owning approximately 10% of the Company.

Also, in connection with the Merger, the Company changed its name from "Anchiano Therapeutics Ltd." to "Chemomab Therapeutics Ltd." (the "Name Change") and the business conducted by Chemomab became primarily the business conducted by the Company, which is a clinical-stage biotech company discovering and developing innovative therapeutics for conditions with high unmet medical need that involve inflammation and fibrosis.

At the Effective Time, each Chemomab ordinary share outstanding immediately prior to the Effective Time (excluding certain Chemomab ordinary shares that were cancelled pursuant to the Merger Agreement) automatically converted into the right to receive, post-reverse split,12.86235 Anchiano ADSs, each representing 20 ordinary shares, plus a warrant that may be exercisable under certain circumstances to purchase ADSs. The exchange ratio was calculated using a formula intended to allocate a percentage of the post-Merger Company to former Chemomab securityholders. Specifically, the exchange ratio was calculated based on a $135.0 million valuation for Chemomab and a $15.0 million valuation for Anchiano (without giving effect to the Reverse Split). In addition, at the Effective Time, Anchiano assumed all outstanding unexercised Chemomab options to purchase Chemomab ordinary shares and each such Chemomab option converted into an option to purchase ordinary shares of the Company (including ordinary shares represented by ADSs), with the number of ordinary shares of the Company subject to such option and the exercise price being appropriately adjusted to reflect the exchange ratio.

Anchiano's ADSs, trading on the Nasdaq Capital Market through the close of business on March 16, 2021 under the ticker symbol "ANCN," will commence trading on the Nasdaq Capital Market, on a post-Reverse Split adjusted basis, under the ticker symbol "CMMB," on March 17, 2021, as of which time the Company's ADS will be represented by a new CUSIP number, 16385C104.

The issuance of the shares of the Company to the former Chemomab securityholders was registered with the SEC on a Registration Statement on Form S-4 (File No. . . .

Item 3.02. Unregistered Sales of Equity Securities.

To the extent required by Item 3.02 of Form 8-K, the information contained in Item 1.01 of this Current Report on Form 8-K is incorporated herein by reference.

Item 3.03 Material Modification to Rights of Security Holders

To the extent required by Item 3.03 of Form 8-K, the information contained in Item 2.01 of this Current Report on Form 8-K is incorporated herein by reference.

As disclosed below under Item 5.07 of this Current Report on Form 8-K, at the special meeting of Anchiano's shareholders held on March 15, 2021 (the "Special Meeting"), the shareholders of Anchiano approved an amendment and restatement of its articles of association (the "Amended and Restated Articles of Association") to (i) increase the registered share capital of Anchiano from 500,000,000 ordinary shares, without par value, to 650,000,000 ordinary shares, without par value, (ii) effect the Reverse Split, (iii) amend the manner in which directors are elected to a classified board format, (iv) effect the Name Change and (v) make such other changes as are set forth in the Amended and Restated Articles of Association.

As a result of the Reverse Split, the number of issued and outstanding ordinary shares of the Company immediately prior to the Reverse Split was reduced to a smaller number of shares, such that every four ordinary shares of the Company held by a shareholder immediately prior to the Reverse Split were combined and reclassified into one share of the Company.

No fractional new ADSs were issued in the Reverse Split. Instead, The Bank of New York Mellon, the Company's depositary in the United States, Depository Trust Company or the relevant securities intermediary would aggregate and sell the fractional entitlement ADSs and deliver net proceeds of the sale to the ADS holders in lieu of their fractional entitlements.

The foregoing description of the Amended and Restated Articles of Association is not complete and is subject to and qualified in its entirety by reference to the Amended and Restated Articles of Association, which are filed as Exhibit 3.1 to this Current Report on Form 8-K, and which is incorporated herein by reference.

Item 5.01 Changes in Control of Registrant

The information required by this Item 5.01 is contained in Item 2.01 and is incorporated by reference herein.

The information set forth in Item 5.02 of this Current Report on Form 8-K regarding the Company's board of directors (the "Board") and principal officers following the Merger are incorporated by reference into this Item 5.01.

Item 5.02 Departure of Directors or Certain Officers; Election of Directors;


          Appointment of Certain Officers




Resignation of Directors



In accordance with the Merger Agreement, Stanislav Polovets, Ruth Alon and Isaac Kohlberg resigned from the Board and any respective committees of the Board of which they were members. The resignations were not the result of any disagreements with Anchiano relating to its operations, policies or practices.





Appointment of Directors


In accordance with the Merger Agreement, on March 16, 2021, effective at the Effective Time, the following individuals were appointed to the Board as directors in the classes set forth below: Stephen Squinto, Ph.D., Adi Mor, Ph.D., Nissim Darvish, M.D., Ph.D, Joel Maryles, Alan Moses, MD, FACP and Claude Nicaise, MD. Neil Cohen, who was a director of Anchiano, continues to serve as a director of the Company.

Other than pursuant to the Merger Agreement, there were no arrangements or understandings between the Company's newly appointed directors and any person pursuant to which they were elected. None of the Company's newly appointed directors has a direct or indirect material interest in any transaction required to be disclosed pursuant to Item 404(a) of Regulation S-K.











Class Designations


Following the Merger, the classes of the Board are as follows:





  • Class I Directors, whose terms expire at the Company's 2022 Annual Meeting:
    Stephen Squinto, Nissim Darvish and Joel Maryles.




  • Class II Directors, whose terms expire at the Company's 2023 Annual Meeting:
    Neil Cohen and Claude Nicaise




  • Class III Directors, whose terms expire at the Company's 2024 Annual Meeting:
    Adi Mor and Alan Moses

Stephen Squinto, Ph.D. will serve on the Board as chairman upon the consummation of the Merger. Dr. Squinto is a Partner at OrbiMed Advisors LLC, an investment firm, and has also served as acting Head of Research and Development of SpringWorks Therapeutics, Inc. Dr. Squinto currently serves on the boards of directors of Passage Bio Inc., SpringWorks Therapeutics, Inc., and several private companies. Dr. Squinto also previously served on the boards of directors of Audentes Therapeutics, Inc. and Arvinas, Inc. Previously, Dr. Squinto co-founded Alexion Pharmaceuticals, a biotechnology company, and served as its Executive Vice President and Chief Global Operations Officer from 2012 to January 2015 and as its Global Head of Research and Development from 2007 to 2012. Dr. Squinto holds a Ph.D. in biochemistry and biophysics and a B.A. in chemistry from Loyola University of Chicago. We believe Dr. Squinto is qualified to serve as a director due to his extensive experience as an entrepreneur and investor in the life sciences industry and his service on the boards of other public and private biopharmaceutical and biotechnology companies.

Adi Mor, Ph.D. will serve on the Board upon the consummation of the Merger. Dr. Mor is a co-founder of Chemomab and has served as Chemomab's Chief Executive Officer, Chief Scientific Officer, member of Chemomab's board of directors since its formation in 2011. She has in-depth knowledge in immunology focusing on rare diseases and broad experience in designing, developing and patenting a novel class of monoclonal antibodies to treat inflammatory and fibrotic diseases. Dr. Mor received her Ph.D. in immunology from Tel Aviv University in the Department of Neurobiochemistry in Israel and is the lead author of numerous scientific journal publications in immunology and inflammatory disorders. Dr. Mor is expected to be appointed to serve on the board of directors of the combined company because of her scientific background and experience in the life sciences industry.

Nissim Darvish, M.D., Ph.D. will serve on the Board upon the consummation of the Merger. Dr. Darvish is a Venture Partner at OrbiMed Israel, an investment firm. Dr. Darvish currently serves as a director of 9 Meters Biopharma Inc. and several private companies. Previously, Dr. Darvish was employed at Pitango Venture Capital, where he was a General Partner managing life sciences . . .

Item 5.03 Amendments to Certificate of Incorporation

The information set forth in Item 3.03 of this Current Report on Form 8-K is incorporated by reference into this Item 5.03.

Item 5.07 Submission of Matters to a Vote of Security Holders

On March 15, 2021, Anchiano held its Special Meeting. The following is a brief description of the final voting results for each of the proposals submitted to a vote of the shareholders at the Special Meeting. The final voting results do not reflect the Reverse Split.

(a) Proposal 1 - The proposal to approve the consummation of the Merger and the other transactions contemplated by the Merger Agreement, including the issuance of Anchiano ordinary shares, to be represented by ADSs, at the Effective Time to the securityholders of Chemomab was approved, as follows:





Votes For    Votes Against   Abstentions
21,038,840      26,420         17,510



(b) Proposal 2 - The proposal to approve the issuance of such number of Anchiano ordinary shares (including ordinary shares represented by ADSs) in the Private Placement was approved, as follows:





Votes For    Votes Against   Abstentions
20,999,475      68,200         15,095



(c) Proposal 3 - The proposal to approve and adopt the Amended and Restated Articles of Association was approved, as follows:





Votes For    Votes Against   Abstentions
21,001,885      66,820         14,065





(d) Proposal 4 - The proposal to approve the form of Indemnification Agreement and to authorize the execution and delivery of such Indemnification Agreement with all directors of the Company to be in office immediately following the Effective Time of the Merger or thereafter elected or appointed to the Board was approved, as follows:





Votes For    Votes Against   Abstentions
21,004,040      47,980         30,750



(e) Proposal 5 - The proposal to approve an amendment to the Company's Compensation Policy to remove the limit on the annual premium for directors and officers insurance was approved, as follows:





Votes For    Votes Against   Abstentions
20,224,320      212,145         7,760



(f) Proposal 6 - The proposal to approve an amendment to the compensation terms of the current and future directors of the Company, and related amendments to the Company's Compensation Policy was approved, as follows:





Votes For    Votes Against   Abstentions
20,139,860      173,170        142,495


Item 8.01 Other Events.



On March 15, 2021, the Company issued a press release announcing the shareholder approval of the Merger and the Private Placement. A copy of the press release is attached as Exhibit 99.1 to this Current Report on Form 8-K.

On March 16, 2021, the Company issued a press release announcing the completion of the Merger, including the Name Change. A copy of the press release is attached as Exhibit 99.2 to this Current Report on Form 8-K.

Item 9.01 Financial Statements and Exhibits

(a) Financial Statements of Chemomab Therapeutics Ltd.

The Company will file the financial statements required to be filed by this Item 9.01(a) not later than seventy-one (71) calendar days after the date on which this Current Report on Form 8-K is required to be filed.

(b) Pro Forma Financial Information.

The Company will file the financial statements required to be filed by this Item 9.01(b) not later than seventy one (71) calendar days after the date on which this Current Report on Form 8-K is required to be filed.





(d) Exhibits Below is a list of exhibits included with this Current Report on
Form 8-K.



Exhibit
No.                                        Document

  2.1*        Agreement and Plan of Merger, dated December 14, 2020, by and among
            Chemomab Therapeutics Ltd. (formerly known as Anchiano Therapeutics
            Ltd.), Chemomab Ltd. and CMB Acquisition Ltd. (incorporated by
            reference to Exhibit 2.1 of the Company's Current Report on Form 8-K
            (File No. 001-38807) filed on December 15, 2020)
  3.1         Amended and Restated Articles of Association of Chemomab
            Therapeutics Ltd. (formerly known as Anchiano Therapeutics Ltd.)
  10.1        Form of Securities Purchase Agreement, dated March 15, 2021, by and
            between Chemomab Therapeutics Ltd. (formerly known as Anchiano
            Therapeutics Ltd.) and certain purchasers
  10.2        Form of American Depositary Shares Purchase Warrant of Chemomab
            Therapeutics Ltd.
  10.3        Form of Anti-Dilution Warrant of Chemomab Therapeutics Ltd.
            (formerly known as Anchiano Therapeutics Ltd.)
  10.4*       Asset Purchase and Assignment Agreement, dated as of March 16, 2021,
            made between Anchiano Therapeutics, Inc. and Kestrel Therapeutics,
            Inc.
  10.5#       Form of Indemnification Agreement of Chemomab Therapeutics Ltd.
            (formerly known as Anchiano Therapeutics Ltd.) (incorporated by
            reference to Exhibit 10.7 of the Company's Registration Statement on
            Form S-4 (File No. 333-252070) filed on February 10, 2021)
  99.1        Press Release, issued on March 15, 2021.
  99.2        Press Release, issued on March 16, 2021.




*   Certain schedules and exhibits to this exhibit have been omitted pursuant to
    Item 601(a)(5) of Regulation S-K. A copy of any omitted schedule and/or
    exhibit will be furnished to the SEC upon request.
#   Indicates a management contract or any compensatory plan, contract or

arrangement.

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