Tempest Therapeutics, Inc. entered into a First Amendment to Loan and Security Agreement (which modified that certain Loan and Security Agreement dated as of Januaryá15, 2021 by and among TempestTX, Inc., a Delaware corporation and wholly owned subsidiary of the Company Oxford Finance LLC as collateral agent, and certain additional lenders party thereto from time to time. Pursuant to the LSA Amendment, (i)áeach of the Company and Millendo Therapeutics US, Inc., a Delaware corporation and wholly owned subsidiary of the were joined as co-borrowers under the Loan Agreement, (ii)áthe interest-only repayment period was extended through Decemberá31, 2023 (which interest-only period may be further extended through Juneá30, 2024 under certain circumstances), and (iii) a security interest in the property of the Company, TempestTx and Millendo, including any intellectual property, was granted to the Lender. In addition, the Lenderá- permitted a one-time prepayment in the amount of $5.0ámillion.