Transgene shares were boosted on Monday morning on the Paris Bourse by the presentation of promising results from a clinical trial dedicated to its therapeutic cancer vaccine project.

The biotech company announced this morning that the study had shown that TG4001 could induce immune responses in HPV16-positive anogenital cancer in an ongoing Phase II trial.

At this stage, 58% of patients who received TG4001 in addition to avelumab (Bavencio) from Merck Serono and Pfizer, showed an increase in immune responses against HPV antigens, compared with 9% in the avelumab arm, says Transgene.

The company points out that, at the start of the study, only four out of 46 patients showed a reaction against HPV antigens, but that the appearance of an immune response was detected after 43 days and tended to intensify after 85 days.

These results were presented in a poster session at the annual meeting of the American Society of Clinical Oncology (ASCO), currently taking place in Chicago.

The share price jumped by around 30% after this announcement, while the CAC Mid & Small index gained just 0.4%.

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