On June 15, 2021, uniQure N.V. appointed Christian Klemt as its Chief Financial Officer. Mr. Klemt was uniQure’s Chief Accounting Officer from August 2017 to June 2021, and he will continue to serve as general manager of uniQure’s Amsterdam site. Matthew Kapusta, who has been uniQure’s Chief Executive Officer since December 2016 and had been its Chief Financial Officer from January 2015 to June 2021, will continue to serve as uniQure’s Chief Executive Officer. In connection with his transition to Chief Financial Officer, Mr. Klemt will also serve as uniQure’s Principal Financial Officer.