April 20 (Reuters) - The UK's main stock indexes dipped on Monday in broad-based losses as fears that the U.S.-Iran ceasefire could collapse weighed on sentiment. 

The U.S. seized an Iranian cargo ship and traffic through the Strait of Hormuz remained largely halted, sending crude oil prices more than 5% higher. 

The blue-chip FTSE 100 index fell 0.6%, while the midcap FTSE 250 slipped 1.2%.

o Heavyweight bank Barclays was down 2.2%, while HSBC dipped 1.1%, bringing the broader banks index 1.7% lower.

o Precious metal miners Fresnillo and Hochschild fell about 2%, tracking a decline in gold and silver prices.

o British Airways owner IAG was down 2.8% as crude prices jumped, while oil giants BP and Shell rose more than 2% each, tracking gains in oil prices.

o The main UK indexes were last week trading at their highest level since early March as hopes of a de-escalation in the Middle East conflict spurred risk-on mood and pushed traders to dial back their bets on Bank of England rate hikes this year.

o Investors were also keeping a close eye on politics as Prime Minister Keir Starmer faces renewed calls to resign over his decision to appoint Peter Mandelson as ambassador to the U.S.

o AstraZeneca said on Monday its experimental treatment showed a "meaningful reduction" in moderate-to-severe flare-ups of chronic obstructive pulmonary disease in a late-stage trial. Shares were down 1.1%.

o Shares of luxury handbag maker Mulberry climbed 7.5% after it reported higher annual revenue.

o Engineering firm Renishaw gained 6.2% after it raised its full-year profit forecast.

(Reporting by Utkarsh Tushar Hathi and Sruthi Shankar; Editing by Shreya Biswas and Keith Weir)