Adaptimmune Therapeutics PLC is focused on pre-clinical programs, including PRAME and CD70-directed T-cell therapies, and its allogeneic pipeline. PRAME is highly expressed across a range of solid tumors, including ovarian, endometrial, lung and breast cancers. The CD70 program targets the CD70 antigen, which is expressed across a range of hematological malignancies (acute myeloid leukemia and lymphoma) and solid tumors (renal cell carcinoma). It is using TRuC technology to develop a T-cell therapy (ADP-520) against CD70, with membrane bound IL-15 to enhance persistence. ADP-520 is in pre-clinical testing. TRuC technology combines the targeting of CAR-T cells with T-cell TCR signaling.

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272

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Pharmaceuticals

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Date	Price	Change	Volume
26-07-27	$0.0300	+2.74%	264,576
26-07-24	$0.0292	-12.97%	141,196
26-07-23	$0.0336	+17.72%	230,657
26-07-22	$0.0285	-5.00%	55,496
26-07-21	$0.0300	-9.09%	169,124

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Market Closed - OTC Markets Other stock markets 03:59:14 2026-07-27 pm EDT			5-day change	1st Jan Change
0.0300 ^USD	+2.74%		-9.09%	+15.38%

May. 18	Adaptimmune Therapeutics plc Reports Earnings Results for the Full Year Ended December 31, 2025	CI
Nov. 17	Adaptimmune Therapeutics plc Announces CEO Changes	CI

Market Cap	7.95M 6.99M 6.51M 5.98M 11.22M 763M 11.37M 77.34M 30.21M 377M 29.85M 29.21M 1.3B	P/E 2024	-1.8x	P/E 2025	0.33x
Enterprise Value	-3.92M -3.44M -3.21M -2.94M -5.53M -376M -5.6M -38.11M -14.88M -186M -14.71M -14.39M -641M	EV / Sales 2024	0.34x	EV / Sales 2025	-0.84x
Free-Float	14.03%	Yield 2024 *	-	Yield 2025	-

May. 18	Adaptimmune Therapeutics plc Reports Earnings Results for the Full Year Ended December 31, 2025	CI
Nov. 17	Adaptimmune Therapeutics plc Announces CEO Changes	CI
Nov. 17	Adaptimmune Therapeutics plc Announces Leadership Changes	CI
25-10-27	Evaxion Names Helen Tayton-Martin as Chief Executive Officer	MT
25-10-26	Adaptimmune Therapeutics plc(OTCPK:ADAP.Y) dropped from NASDAQ Composite Index	CI
25-10-24	European Equities Traded in the US as American Depositary Receipts Flat in Friday Trading	MT
25-10-23	European Equities Traded in the US as American Depositary Receipts Rise in Thursday Trading	MT
25-10-22	European Equities Traded in the US as American Depositary Receipts Rise in Wednesday Trading	MT
25-10-21	European Equities Traded in the US as American Depositary Receipts Decline in Tuesday Trading	MT
25-10-20	Top Midday Decliners	MT
25-10-20	European Equities Close Mostly Higher in Monday Trading; UK Sentiment Sees 'Some of the Gloom Lift'	MT
25-10-20	European Equities Traded in the US as American Depositary Receipts Rise in Monday Trading	MT
25-10-20	Adaptimmune Therapeutics to Voluntarily Delist From Nasdaq	MT

25-07-30	Guggenheim Downgrades Adaptimmune Therapeutics to Neutral From Buy	MT
25-07-29	HC Wainwright Downgrades Adaptimmune Therapeutics to Neutral From Buy	MT
25-06-26	Mizuho Downgrades Adaptimmune Therapeutics to Neutral From Outperform, Cuts Price Target to $0.50 From $1.50 on Solvency Concerns	MT
24-11-27	Mizuho Cuts Price Target on Adaptimmune Therapeutics to $1.50 From $3, Keeps Outperform Rating	MT
24-07-30	HC Wainwright Starts Adaptimmune Therapeutics With Buy Rating, $4 Price Target	MT

Adaptimmune Therapeutics plc Stock

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US00653A1079

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Nov. 17	Adaptimmune Announces Changes to Board and Executive Leadership Team	NE
25-10-20	Adaptimmune Announces Delisting from Nasdaq	NE
25-08-13	Adaptimmune Reports Q2 Financial Results and Provides Business Update	NE
25-07-28	Adaptimmune Announces Entry into Definitive Agreement for Sale of TECELRA, lete-cel, afami-cel and uza-cel Cell Therapies to US WorldMeds	NE
25-05-13	Adaptimmune Reports Q1 Financial Results and Provides Business Update	NE

24-05-30	Galapagos gaat samenwerken met Adaptimmune
24-04-12	Roche: Genentech met fin à la collaboration avec Adaptimmune Therapeutics
24-04-12	Roche-Tochter Genentech beendet Zusammenarbeit mit Adaptimmune Therapeutics
23-04-11	GSK : Adaptimmune reprend les droits de deux programmes
21-09-07	Aktien Schweiz Schluss: SMI unter Druck

1 day	+2.74%
1 week	-9.09%
Current month	-17.81%
1 month	-22.88%
3 months	+488.24%
Current year	+15.38%

1 week	0.03	0.04
1 month	0.02	0.05
Current year	0	0.05
1 year	0	0.28
3 years	0	2.05
5 years	0	6.86
10 years	0	14.62

Manager	Title	Age	Since
Christopher Hill CEO	Chief Executive Officer	46	2025-11-13
Juli P. Miller IRC	Investor Relations Contact	-	2016-07-31
Phil Bassett PRN	Corporate Officer/Principal	-	-

Director	Title	Age	Since
Lawrence Alleva CHM	Chairman	76	2025-11-13
Garry Menzel BRD	Director/Board Member	61	2023-05-31
Christopher Hill BRD	Director/Board Member	46	2025-11-13

Date	Insider	Type	Main position	Quantity	% Market Cap.
9/2/25	Gavin Wood	Sell	Chief Financial Officer	96,000	0.0060%
8/28/25	William Bertrand	Sell	Compliance Officer	207,000	0.0130%
8/15/25	NEA Management Co. LLC	Sell	Company	19,500,000	7.3571%

Add to a list 0 selected To use this feature you must be a member Log in Sign up	Change	5-day change	1-year change	3-year change	Capi.($)
ADAPTIMMUNE THERAPEUTICS PLC	+2.74%	-9.09%	-91.35%	-96.55%	7.95M
REGENERON PHARMACEUTICALS, INC.	+1.70%	-0.74%	+18.48%	-10.41%	67.88B
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SAMSUNG BIOLOGICS CO.,LTD.	+1.78%	+54.50%	+54.50%	+54.50%	48.71B
CSL LIMITED	+2.69%	-1.53%	-55.83%	-55.20%	38.98B
BIOGEN INC.	-1.01%	+0.10%	+52.17%	-23.84%	29.55B
INCYTE CORPORATION	+1.02%	+2.78%	+69.33%	+89.65%	23.75B
MODERNA, INC.	+2.89%	-6.49%	+62.90%	-53.06%	22.07B
BRIDGEBIO PHARMA, INC.	+0.12%	+4.16%	+81.68%	+161.81%	16.49B
SWEDISH ORPHAN BIOVITRUM AB	-1.36%	-1.59%	+62.38%	+122.14%	16.57B
Average	+1.03%	-0.01%	+29.14%	+39.66%	31.72B
Weighted average by Cap.	+1.04%	+1.41%	+33.61%	+49.77%

	2024	2025
Net sales	178M 157M 146M 134M 251M 17.07B 255M 1.73B 676M 8.43B 668M 654M 29.14B	5.92M 5.21M 4.85M 4.45M 8.36M 568M 8.47M 57.62M 22.51M 281M 22.24M 21.76M 970M
Net income	-70.81M -62.25M -57.95M -53.22M -99.93M -6.79B -101M -689M -269M -3.35B -266M -260M -11.59B	25.21M 22.16M 20.63M 18.94M 35.57M 2.42B 36.04M 245M 95.76M 1.19B 94.62M 92.58M 4.13B
Net Debt	-77.4M -68.04M -63.34M -58.17M -109M -7.42B -111M -753M -294M -3.66B -291M -284M -12.67B	-11.87M -10.43M -9.71M -8.92M -16.75M -1.14B -16.97M -115M -45.09M -562M -44.56M -43.59M -1.94B