Valuation: Septerna, Inc.

Capitalization 467M 405M 381M 346M 641M 40.41B 722M 4.51B 1.73B 18.51B 1.75B 1.71B 68.04B P/E ratio 2025 *
15.2x
P/E ratio 2026 * -6.16x
Enterprise value 42.62M 36.97M 34.83M 31.64M 58.54M 3.69B 65.96M 412M 158M 1.69B 160M 157M 6.22B EV / Sales 2025 *
0.31x
EV / Sales 2026 * -5.22x
Free-Float
98.36%
Yield 2025 *
-
Yield 2026 * -
More valuation ratios * Estimated data
Dynamic Chart
1 day-0.19%
1 week+2.95%
Current month+13.19%
1 month+15.56%
3 months+76.86%
6 months-56.88%
Current year-54.28%
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1 week 9.85
Extreme 9.8515
10.75
1 month 9.04
Extreme 9.045
10.98
Current year 4.17
Extreme 4.17
23.85
1 year 4.17
Extreme 4.17
28.99
3 years 4.17
Extreme 4.17
28.99
5 years 4.17
Extreme 4.17
28.99
10 years 4.17
Extreme 4.17
28.99
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Manager TitleAgeSince
Chief Executive Officer 59 2021-10-31
Director of Finance/CFO 53 2025-01-05
Chief Tech/Sci/R&D Officer 56 2024-08-31
Director TitleAgeSince
Director/Board Member 59 2021-10-31
Chairman 49 2021-10-31
Director/Board Member 40 2021-10-31
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Change 5d. change 1-year change 3-years change Capi.($)
-0.19%+2.95% - - 467M
+0.39%-1.51%+17.39%+14.44% 48.43B
-2.25%-8.36%+58.27%+61.84% 29.32B
+0.08%-1.38%-28.45%-22.16% 26.77B
+1.25%+0.87%+0.01%+19.62% 26.16B
-40.00%+142.71%+35,996.87%+3,366.80% 18.8B
+0.10%-1.36%+12.82%-18.13% 12.32B
-1.14%-4.17%+138.51% - 11.83B
+2.02%+0.56%-54.05%-28.64% 11.64B
+3.63%+3.57%+38.37%+106.90% 10.68B
Average -3.61%+13.33%+4,019.97%+437.58% 19.64B
Weighted average by Cap. -3.64%+11.78%+3,470.28%+360.10%
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Financials

2025 *2026 *
Net sales 137M 119M 112M 102M 189M 11.9B 213M 1.33B 509M 5.45B 515M 504M 20.03B 31.25M 27.11M 25.53M 23.2M 42.92M 2.71B 48.36M 302M 116M 1.24B 117M 115M 4.56B
Net income -54.31M -47.11M -44.38M -40.32M -74.6M -4.7B -84.05M -525M -201M -2.15B -204M -199M -7.92B -77.23M -66.99M -63.1M -57.33M -106M -6.69B -120M -747M -286M -3.06B -290M -284M -11.26B
Net Debt -424M -368M -346M -315M -582M -36.71B -656M -4.1B -1.57B -16.82B -1.59B -1.56B -61.83B -630M -546M -515M -468M -865M -54.55B -975M -6.09B -2.33B -24.99B -2.36B -2.31B -91.86B
More financial data * Estimated data
Logo Septerna, Inc.
Septerna, Inc. is a clinical-stage biotechnology company. The Company is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. It is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with significant unmet needs. It is focused in major therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.
Employees
75
More about the company
Date Price Change Volume
25-06-20 10.47 $ -0.19% 967,609
25-06-18 10.49 $ +2.44% 490,258
25-06-17 10.24 $ -2.85% 536,324
25-06-16 10.54 $ +3.64% 345,499
25-06-13 10.17 $ -2.31% 299,659

Delayed Quote Nasdaq, June 20, 2025 at 04:00 pm EDT

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Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
4
Last Close Price
10.47USD
Average target price
23.67USD
Spread / Average Target
+126.04%
Consensus

Quarterly revenue - Rate of surprise