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IntelGenx Technologies : Granted Japanese Patent for RIZAPORT VersaFilm

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02/12/2019 | 08:06am EST

SAINT LAURENT - IntelGenx Corp. (TSX-V:IGX) (OTCQX:IGXT) ('IntelGenx'), a leading oral drug delivery company, today announced that it has received a Decision to Grant notice from the Japanese Patent Office (JPO) to issue a patent entitled 'Instantly wettable oral film dosage form without surfactant or polyalcohol.'

Once the JPO's administrative process is complete, the patent that issues from this application will provide intellectual property protection in Japan for the formulation of IntelGenx' VersaFilm technology used in its RIZAPORT product, through 2034. RIZAPORT is an oral thin film formulation of rizatriptan benzoate for the treatment of acute migraines. The Decision to Grant notice is the final approval stage and precedes actual granting, which is expected shortly. The identification number is Japanese Patent Application 2016-530631. IntelGenx received a similar formulation patent covering its RIZAPORT VersaFilm technology from the European Patent Office in 2018 and from the United States Patent and Trademark Office in 2016, and has additional applications pending in other countries. 'This allowance adds to the formidable intellectual property estate that we are building for RIZAPORT around the globe,' said Dr. Horst G. Zerbe, President and CEO of IntelGenx. 'Japan is the world's third-largest pharmaceuticals market and, as such, represents a significant commercial opportunity for RIZAPORT . Moving forward, we will be actively seeking a marketing partner for the product in this jurisdiction.'


RIZAPORT is a patent protected proprietary oral thin film formulation of rizatriptan benzoate, a 5-HT1 receptor agonist and the active drug in Merck & Co.'s Maxalt .

Rizatriptan is considered to be one of the most effective oral triptans, a class of molecules that constricts blood vessels in the brain to relieve swelling and other migraine symptoms. RIZAPORT is based on IntelGenx' proprietary VersaFilm technology. It dissolves rapidly and releases its active ingredient in the mouth. The administration method of the RIZAPORT oral soluble film, which does not require the patient to swallow a pill or consume water, along with its neutral flavor, presents a potentially attractive therapeutic alternative for migraine patients, specifically for patients who suffer from migraine-related nausea, estimated to be approximately 80% of the total migraine patient population and patients suffering from dysphagia (difficulty swallowing)1 .

About IntelGenx

Established in 2003, IntelGenx is a leading oral drug delivery company primarily focused on the development and manufacturing of innovative pharmaceutical oral films based on its proprietary VersaFilm technology platform. IntelGenx's highly skilled team provides comprehensive pharmaceuticals services to pharmaceutical partners, including R&D, analytical method development, clinical monitoring, IP and regulatory services. IntelGenx's state-of-the-art manufacturing facility, which was established for the VersaFilm technology platform, offers by supporting lab-scale to pilot- and commercial -scale production. More information about the company can be found at www.intelgenx.com.

Forward Looking Statements

This document may contain forward-looking information about IntelGenx' operating results and business prospects that involve substantial risks and uncertainties. Statements that are not purely historical are forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended. These statements include, but are not limited to, statements about IntelGenx' plans, objectives, expectations, strategies, intentions or other characterizations of future events or circumstances and are generally identified by the words 'may,' 'expects,' 'anticipates,' 'intends,' 'plans,' 'believes,' 'seeks,' 'estimates,' 'could,' 'would,' and similar expressions. All forward looking statements are expressly qualified in their entirety by this cautionary statement. Because these forward-looking statements are subject to a number of risks and uncertainties, IntelGenx's actual results could differ materially from those expressed or implied by these forward-looking statements. Factors that could cause or contribute to such differences include, but are not limited to, those discussed under the heading 'Risk Factors' in IntelGenx's annual report on Form 10-K, filed with the United States Securities and Exchange Commission and available at www.sec.gov, and also filed with Canadian securities regulatory authorities at www.sedar.com. IntelGenx assumes no obligation to update any such forward-looking statements.


Tel: (514) 331-7440

(C) 2019 Electronic News Publishing, source ENP Newswire

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Financials ($)
Sales 2018 1,37 M
EBIT 2018 -9,80 M
Net income 2018 -10,8 M
Debt 2018 -
Yield 2018 -
P/E ratio 2018 -
P/E ratio 2019
Capi. / Sales 2018 46,1x
Capi. / Sales 2019 8,60x
Capitalization 63,3 M
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Horst G. Zerbe Chairman, President & Chief Executive Officer
André Godin Chief Financial Officer & Executive Vice President
Nadine Paiement Vice President-Research & Development
Bernd Josef Melchers Independent Director
J. Bernard Boudreau Vice Chairman