On March 27, 2023, Karim Mikhail notified Amarin Corporation plc (the Company) of his decision to resign as President of the Company, effective immediately. Mr. Mikhail has asserted that he is entitled to severance payments as the result of his resignation, which the Company disagrees with and intends to dispute. The Company is in the process of identifying a permanent replacement for Mr. Mikhail.

The Board is also announcing that it has appointed Odysseas D. Kostas as chairperson of the Board.