There are certain forms of cancer that are more deadly. Glioblastoma (GBM) is a highly aggressive type of brain cancer with no cure, leading to a grim prognosis and average survival time of only 14 to 16 months. Oftentimes, people first become suspicious that something might be wrong when a persistent headache occurs followed by intensifying pain and bouts of dizziness and blurred vision, and it is a highly invasive tumor that makes complete surgical removal difficult.
The diagnostic process begins with a series of tests: MRI scans, CT scans and a battery of examinations. People who decide to seek treatment often face a grueling experience, yet the prognosis remains grim. The cancer rapidly infiltrates healthy tissue, evading the most advanced medical interventions. Current treatments like surgery, chemotherapy and radiation are not very effective in prolonging survival. However, there is growing interest in developing treatments that target specific genetic mutations and molecular pathways involved in glioblastoma growth, including immunotherapy and precision medicine.
Taking A Different Approach:
In September, the company announced that 200 out of 243 expected patients had been enrolled in their ongoing study evaluating the effectiveness of Berubicin for recurrent GBM, a highly aggressive and incurable form of brain cancer. This global study of Berubicin is a critical and adaptive trial that involves multiple centers and is open-label. It is randomized and controlled, comparing Berubicin to Lomustine - the standard of care - in adult patients with recurrent GBM (WHO Grade IV) after standard first-line therapy has failed. The primary goal of the study is Overall Survival (OS), a rigorous measure that the FDA recognizes as fundamental for approving oncology drugs when there is a statistically significant improvement compared to a randomized control arm. Currently, the company has opened 46 clinical trial sites out of approximately 60 selected locations across
The company reports that its interim analysis is also showing promising results.
Experienced Management
At the helm of this groundbreaking enterprise is a management team comprising visionary leaders with extensive experience in the field of oncology and drug development. Leading the charge is
Assisting him in this mission is
Together, Climaco, Silberman and the rest of the dedicated management team at
Contact:
Email: justin@jtcir.com
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