Neoleukin Therapeutics, Inc. announced treatment of the first patient in a combination arm evaluating the safety and efficacy of Neoleukin's NL-201 in combination with Merck's anti-PD-1 therapy KEYTRUDA® (pembrolizumab), as part of Neoleukin's ongoing Phase 1 trial in patients with relapsed or refractory solid tumors. Up to 132 patients will be enrolled in the combination arm of the study, which is being conducted through a clinical collaboration and supply agreement with Merck (known as MSD outside the United States and Canada). The trial is assessing safety, pharmacokinetics, pharmacodynamics, immunogenicity, and antitumor activity.

KEYTRUDA® is a registered trademark of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA.