Peter Thompson and Nassim Usman each resigned from the Board of Directors of Principia Biopharma Inc, effective upon the closing of the company's initial public offering. At the time of these resignations, each of Dr. Thompson and Dr. Usman was an independent director. Each of Dr. Thompson and Dr. Usman indicated that his decision to resign was not a result of any disagreement with the company on any matter relating to the Company's operations, policies or practices.