Item 8.01 Other Events

On December 16, 2020, Proteostasis Therapeutics, Inc. ("Proteostasis" or the "Company") adjourned its special meeting of stockholders, held on December 16, 2020 at 9:00 AM Eastern, to December 22, 2020 at 9:00 AM Eastern, in order to provide stockholders sufficient time to consider new information pertaining to the Company's entry into a subscription agreement on December 14, 2020 with certain purchasers for the sale by the Company in a private placement of shares of the Company's common stock. Accordingly, the record date for the Proteostasis stockholders entitled to receive a dividend in the form of a contingent value right, which is immediately prior to the effectiveness of the merger, is now anticipated to be December 22, 2020. Stockholders did not vote on any of the proposals prior to adjournment and all proposals will be voted on at the reconvened meeting.

The Proteostasis special meeting will be reconvened on December 22, 2020 at 9:00 AM Eastern for stockholders to vote on all proposals. The reconvened special meeting will be held in a virtual-only format via live audio webcast at www.proxydocs.com/PTI.

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