Timothy Sinclair
Director/Board Member at Ambiente Tapas Ltd.
Profile
Charles Sinclair joined Flagship Pioneering in 2022 as Senior Director of Translational Sciences for Pioneering Medicines.
He is head of the Translational Sciences function, accountable for translational research and biomarker strategy in support of the Pioneering Medicines portfolio.
Charles has experience spanning multiple therapeutic areas and modalities.
Prior to Flagship, he was a Senior Principal Scientist at Bristol Myers Squibb (BMS), where he served as a program lead for multiple discovery stage small molecule programs that targeted mechanisms of tumor-intrinsic cancer resistance.
Prior to BMS, he was an immuno-oncology Team Leader within the bioscience group at AstraZeneca (Cambridge, UK) and was the biology lead of a FOXP3-targeted antisense oligonucleotide program that is currently in Ph1a/b clinical trials.
Before joining the biotech industry, Charles was a postdoctoral researcher and Marie Curie CASCADE fellow at Emory University studying immuno-metabolic crosstalk during inflammatory diseases and vaccination.
He had previously completed a Ph.D.
and short postdoc at the MRC National Institute for Medical Research (London, UK) studying T-cell homeostasis and development.
Charles has published papers and review articles in areas of immunology, immuno-oncology and cancer, including first/corresponding author publications in Science, Proceedings of the National Academy of Sciences, and Oncoimmunology.
Charles received a B.Sc.
degree (first class hons) from the University of Warwick (Warwick, UK), and a Ph.D.
from the MRC National Institute for Medical Research (London, UK).
Timothy Sinclair active positions
Companies | Position | Start |
---|---|---|
Ambiente Tapas Ltd.
Ambiente Tapas Ltd. RestaurantsConsumer Services Ambiente Tapas Ltd. is a British company that operates restaurants. The private company is based in York, UK. The company was founded in 2007. | Director/Board Member | 2007-04-15 |
Flagship Pioneering
Flagship Pioneering Investment ManagersFinance Flagship Pioneering (Flagship Pioneering) is a venture capital firm founded in 1982 by Ed M Kania and Noubar B Afeyan. The firm is headquartered in Cambridge, Massachusetts. | Director/Board Member | 2022-12-31 |
Former positions of Timothy Sinclair
Companies | Position | End |
---|---|---|
BRISTOL-MYERS SQUIBB COMPANY | Chief Tech/Sci/R&D Officer | 2022-01-30 |
Training of Timothy Sinclair
University of Warwick | Undergraduate Degree |
The National Institute For Medical Research | Doctorate Degree |
Experiences
Positions held
Connections
1st degree connections
1st degree companies
Male
Female
Members of the board
Executives
Linked companies
Listed companies | 1 |
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BRISTOL-MYERS SQUIBB COMPANY | Health Technology |
Private companies | 2 |
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Flagship Pioneering
Flagship Pioneering Investment ManagersFinance Flagship Pioneering (Flagship Pioneering) is a venture capital firm founded in 1982 by Ed M Kania and Noubar B Afeyan. The firm is headquartered in Cambridge, Massachusetts. | Finance |
Ambiente Tapas Ltd.
Ambiente Tapas Ltd. RestaurantsConsumer Services Ambiente Tapas Ltd. is a British company that operates restaurants. The private company is based in York, UK. The company was founded in 2007. | Consumer Services |
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