Up to Tuesday's close, the broader technology-heavy Nasdaq Composite index had lost 4.5% since Feb. 12, compared with a 0.3% rise in the blue-chip Dow. The benchmark S&P 500 slipped 1.4% in the same period.

By 1:40 a.m. ET on Wednesday, Nasdaq 100 e-minis were down 109.5 points, or 0.83%, Dow e-minis were down 100 points, or 0.32%, and S&P 500 e-minis were down 15.5 points, or 0.4%.

(Reporting by Sagarika Jaisinghani in Bengaluru; Editing by Subhranshu Sahu)