AdAlta Ltd (ASX:1AD) CEO Tim Oldham tells Proactive the company has successfully dosed the first participants in its AD-214 Phase I extension study, marking the next milestone in the drug's development. AD-214 is being developed to target fibrotic diseases. AdAlta is on track to achieve interim results from the study before the end of 2023, providing a glimpse into the drug's potential. The final assessment visits are expected to be completed, and full results are anticipated to be available in the first quarter of 2024.
“We extend our gratitude to the volunteers who are participating in this extension study,” Oldham said.
“Their involvement is essential in advancing a potential new therapy for sufferers of debilitating and incurable idiopathic pulmonary fibrosis and other fibrotic diseases.”
AdAlta will be holding an online briefing discussing progress of the AD-214 Phase 1 extension study on Thursday 10 August at 10:30am (AEDT).
To participate in the live webcast, shareholders, investors and interested parties are invited to click on the link below to register:
AdAlta Limited is an Australia-based clinical-stage biotechnology company. The Company uses its i-body platform to discover and develop protein therapeutics addressing drug targets that are challenging for other technologies. The Company's first-in-class lead asset, AD-214, is being developed for the treatment of idiopathic pulmonary fibrosis (IPF) and other fibrotic diseases, for which current therapies are sub-optimal. AD-214 is an Fc-Fusion protein that contains two AD-114 i-body molecules at the front end, that bind with high affinity to the human target, CXCR4. It is also engaged in developing i-body enabled Chimeric antigen receptor T cell (CAR-T) cells. It co-develops i-bodies as diagnostic imaging agents (i-PET imaging) against Granzyme B, a biomarker of response to immuno-oncology drugs.