Cardiovascular : Stifel MedTech Madness 2022 Annual West Coast Bus Tour

Transformational Growth

Stifel MedTech Madness 2022 Annual West Coast Bus Tour

December 13, 2022

Scott R. Ward

Chairman, President & CEO

Safe Harbor

Forward Looking Statements

This presentation contains forward-looking statements within the meaning of the Private Securities Litigation Report Act of 1995, which are provided under the protection of the safe harbor for forward-looking statements provided by that Act.

For example, statements in this presentation regarding CSI's strategy, goals, growth, future financial measurements, product development and introductions, geographic expansion, reimbursement expectations, acquisition of products in development, distributed products, clinical trials, future investments and financing needs, and market opportunities, are forward-looking statements. These statements involve risks and uncertainties that could cause results differ materially from those projected, including, but not limited to, those described in CSI's filings with the Securities and Exchange Commission, including its most recent annual report on Form 10-K and subsequent quarterly and annual reports. CSI encourages you to consider all of these risks, uncertainties and other factors carefully in evaluating the forward-looking statements contained in this presentation. As a result of these matters, changes in facts, assumptions not being realized or other circumstances, CSI's actual results may differ materially from the expected results discussed in the forward-looking statements contained in this presentation. The forward-looking statements contained in this presentation are made only as of the date of this presentation, and CSI undertakes no obligation to update them to reflect subsequent events or circumstances.

Financial Disclaimers

Financial Information

This presentation includes calculations or figures that have been prepared internally and have not been reviewed or audited by CSI's independent registered accounting firm. Use of different methods for preparing, calculating or presenting information may lead to differences, which may be material.

Market Estimates

Unless noted otherwise, any references to market sizes, market share positions, and market growth rates are CSI internal estimates.

Non-GAAP Financial Measures

This presentation also refers to certain non-GAAP financial measures, such as Adjusted EBITDA. Non-GAAP financial measures have limitations as analytical tools and should not be considered in isolation or as a substitute for CSI's financial results prepared in accordance with GAAP.

Focused Transformation

Grow and protect the core while we expand into larger and faster growing markets

Grow and protect

Expand global Orbital Atherectomy franchises

Focused on our complex coronary and peripheral patient population

Leveraging the capacity and competency of our U.S. sales channel

Innovation to pursue larger and faster growing markets

Broaden product portfolio beyond atherectomy

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