Cyprotex PLC
("Cyprotex" or "the Company")


Grant of Options

Further to the announcement made on 23 January, the Company announces today that Tony Baxter, Chief Executive Officer of the Company, has been granted 20,000,001 options, all over ordinary shares of 0.1p each as part of the executive share option scheme.
The vesting of these executive options is on grant, at an exercise price of 6 pence per share, and are exercisable only upon change of control of the Company within a ten year period, dependent upon the Company's share price performance and subject to a minimum share price of 12 pence.

For further information:

Cyprotex PLC
Tel: +44 (0) 1625 505 100
Dr Anthony Baxter, Chief Executive Office
John Dootson, Chief Financial Officer
Mark Warburton, Chief Operating Officer and Legal Counsel
ir@cyprotex.com
www.cyprotex.com

N+1 Singer (Nomad and broker to Cyprotex)
Tel: +44 (0)20 7496 3000
Shaun Dobson
shaun.dobson@n1singer.com
Jenny Wyllie
jenny.wyllie@n1singer.com
www.nplus1singer.com

FTI Consulting
Simon Conway
Mo Noonan
Tel: +44 (0) 20 7831 3113
cyprotex@fticonsulting.com
www.fticonsulting.com

About Cyprotex PLC

Cyprotex is based in Macclesfield, near Manchester in the UK, and Watertown, MA in the US and is listed on the AIM market of the London Stock Exchange (CRX). The company was established in 1999 and works with more than 700 partners ranging from small biotech's to large pharma companies. Cyprotex acquired Apredica and the assets of Cellumen Inc. in August 2010 and the combined business provides support for a wide range of experimental and computational ADME-Tox and PK services, extending from early drug discovery through to IND submission. The company's core capabilities include high quality in vitro ADME screening services, mechanistic toxicology and high content toxicology screening services, including our proprietary CellCiphr® toxicity prediction technology, and predictive modelling using PBPK and QSAR techniques, including Cloe® PK for in vivo PK prediction. For more information, see www.cyprotex.com.


Dr Anthony Baxter, CEO of Cyprotex, commented:
"We are pleased that the Board has set forth an incentive scheme for senior managers which will encourage the continuation of the excellent scientific and fiscal performances that the business has seen over the past 5 years and assist in continuing to improve shareholder returns.

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