On November 22, 2016, HedgePath Pharmaceuticals, Inc. entered into Amendment No. 1 to Second Amended and Restated Supply and License Agreement with Mayne Pharma Ventures Pty Ltd., the current majority stockholder of the company. On November 22, 2016, pursuant to that certain Amended and Restated Equity Holders Agreement, the company removing Frank E. O’Donnell, Jr, M.D. as Executive Chairman of the Board of Directors and as a director of the company and electing E. Brendan Magrab as Chairman of the Board of Directors and as a director of the company. Since March 2013, Mr. Magrab has served as the President and CEO of Transpharmative Advisors, LLC. Mr. Magrab has more than 20 years of experience in pharmaceutical development and marketing, including formulation development, clinical development, regulatory affairs, government affairs, marketing, managed care, legal and patents. Previously, from June 2012 to February 2013, he served as the President and CEO of URL Pharma. From October 2004 to June 2012, he held various positions of increasing responsibility at URL Pharma, including General Counsel and Executive Vice President of Commercial Operations. Prior to joining URL Pharma, from August 2000 to September 2004, Mr. Magrab served as Vice President of Intellectual Property at Alpharma, Inc.