ISpecimen : Presentation

The Online Marketplace for Human Biospecimens

Transforming Biospecimen Procurement

March 2024

Investor Presentation

Nasdaq: ISPC

Forward-Looking Statements

This presentation may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Such forward-looking statements are characterized by future or conditional verbs such as "may," "will," "expect," "intend," "anticipate," "believe," "estimate" and "continue" or similar words. You should read statements that contain these words carefully because they discuss future expectations and plans, which contain projections of future results of operations or financial condition or state other forward- looking information. Such statements are only predictions and our actual results may differ materially from those anticipated in these forward-looking statements.

We believe that it is important to communicate future expectations to investors. However, there may be events in the future that we are not able to accurately predict or control. Factors that may cause such differences include, but are not limited to, those discussed under Risk Factors in our filings filed with the Securities and Exchange Commission (the "SEC"), including the uncertainties associated with our lack of profitability, our continued capital needs, our lack of a long operating history, our growth strategy, the uncertain effect of geopolitical developments, our technology development plans, and the regulatory environment in which we operate. We do not assume any obligation to update forward-looking statements as circumstances change.

Certain market data information in this presentation is based on management's estimates. We obtained the industry, market and competitive position data used throughout this presentation from internal estimates and research as well as from industry publications and research, surveys and studies conducted by third parties. We believe our estimates to be accurate as of the

date of this presentation. However, this information may prove to be inaccurate because of the method by which we obtained

some of the data for our estimates or because this information cannot always be verified due to the limits on the availability and reliability of raw data, and the nature of the data gathering process.

You may access our SEC filings by visiting the SEC's website at http://www.sec.gov. This presentation does not constitute an offer or invitation for the sale or purchase of securities or to engage in any other transaction with us or our affiliates. The information in this presentation is not targeted at the residents of any particular country or jurisdiction and is not intended for distribution to, or use by, any person in any jurisdiction or country where such distribution or use would be contrary to local law

or regulation.

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Our Vision

To transform the biospecimen industry with an online marketplace connecting researchers to patients, biospecimens, and data, through our global network.

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Investor Highlights

1. Similar to Amazon, iSpecimen has developed an online marketplace to seamlessly connect researchers with healthcare providers and supplier organizations
2. First mover advantage that addresses an inefficient and fragmented global biospecimen supply chain that is poised to be disrupted by an online solution
3. $3B-$4Bglobal biospecimen market growing at 10-15%per year 1,2
4. Strong revenue growth with an 8-year CAGR of 39% fueled by precision and regenerative medicine research
5. Plans to enhance existing platform and develop new service offering to increase revenue opportunities

>220

Healthcare Provider / Supplier

Organizations

>600

Customer

Organizations

1,2 "Sources Cited" page 31

Biospecimens are Essential for Life Science R&D

SUPPLY SIDE

HEALTHCARE PROVIDERS

DEMAND SIDE

LIFE SCIENCE RESEARCHERS

Patients

Biospecimens

Data

Biofluids

Plasma, Serum, Urine, Saliva

Medical

Record

Solid Tissue

Lung, Breast, Colon, Brain

Stem & Immune Cells

Organizations

Industry

Academia

Applications

Basic Research

Biomarker

Identification &

Validation

Drug Discovery &

Development

Bone Marrow, Blood, Tonsils, Lymph Nodes

Government	Diagnostics
			Discovery &
			Validation

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Biospecimen Supply Chain Challenges

Providers miss revenue and

research opportunities

> 1 Billion

Patient encounters yearly in the U.S. where a specimen could be provided for research 3

> 3 Billion

clinical specimens are discarded

annually worldwide 4

> 800 Million

banked specimens are in biorepository

inventories worldwide 5

Researchers limit

their work

10 years ago, 81%

of researchers said they limit the scope of their work

due to difficulties obtaining biospecimens 6

… in 2022, 78%

of researchers said they find it difficult-to-extremely difficult to find

the type and quantity of specimens they need 7

"Challenging" and "Inefficient"

most common words used to describe biospecimen procurement process by researchers 7

3,4,5,6,7,8 "Sources Cited" page 31

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Biospecimen Supply Chain Challenges

-Difficult to Connect, Search and Compliantly Transact -Average time to develop relationships is 6-12 months ᶟ

PROVIDERS

CHALLENGE

RESEARCHERS

8 "Sources Cited" page 31

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The iSpecimen Marketplace® Solution

-iSpecimen Customer Base: 70% of the Top 20 Pharma Companies and IVD Companies Worldwide

PROVIDERS

SOLUTION

RESEARCHERS

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Full-Service Procurement Offering

-Connect Suppliers with Researchers

-Manage the Entire Procurement Process

iSpecimen Services

CONTRACTING

COMPLIANCE MANAGEMENT

STUDY DESIGN & SPECIFICATION

SPECIMEN SEARCH & SELECTION

STUDY/ORDER MANAGEMENT

COLLECTION KIT BUILDING

SUPPLIER SITE TRAINING

SPECIMEN LOGISTICS

SPECIMEN MANAGEMENT

DATA MANAGEMENT

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iSpecimen Value Proposition

Providers…

Monetize Banked Biospecimens

Instantly connect to a global network of researchers in search for biospecimens

Advance Scientific Discovery

Support research mission and advance diagnostic, therapeutic and vaccine research

Ensure Compliance

Protect the privacy and security of patient information

Researchers…

Save Time and Money

Instantly connect to global network of specimen providers

Accelerate Research

Search for specimens anytime, anywhere, through easy-to-use online marketplace

Reduce Risk

Manage contracting and regulatory compliance

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