On December 3, 2021, Jerry Schneider informed the Board of Directors of Kiromic Biopharma, Inc. that he was resigning his position as director of the Registrant effective immediately due to personal reasons. Mr. Schneider also ceased to be a member of the Audit Committee, and the Compensation Committee of the Board. Mr. Schneider’s resignation did not involve a disagreement with the Registrant on any matter relating to the Registrant’s operations, policies or practices.