For Researchers Who Need Flexible Throughput, the Guava® Multi-Antigen Antibody Flow Cytometry Assay is Now Available
Posted on June 16, 2021 (Updated on June 15, 2021) byKatie Gillis
Kit provides comprehensive profile of antibody isotypes against multiple SARS-CoV-2 antigens

Throughout the COVID-19 pandemic, we've developed tools and assays to support diagnostics, infection control, safety measures, vaccine development, and research. As we continue to manage this evolving public health threat, there is a rising need for insight into the SARS-CoV-2 antibody response and how it changes over time.

To help address this, we're excited to announce the launch of the Guava® SARS-CoV-2 Multi-Antigen Antibody Kit-a new, easy-to-use serological assay for our flow cytometry platforms that offers rapid results.

Features to support modern flow cytometry research

The Guava® SARS-CoV-2 Multi-Antigen Antibody Kit detects IgG, IgM, and IgA antibodies against three SARS-CoV-2 antigens in parallel-the nucleocapsid protein, the receptor binding domain of the spike protein, and the S1 subunit of the spike protein. The kit can be used for serum and plasma samples and was designed to run on the Guava® Muse® Cell Analyzer and Guava® easyCyte™ flow cytometry systems, though it can be used with any flow cytometer equipped with a 488 nm or 532 nm laser.

For maximum ease of use, the Guava Muse Cell Analyzer and Guava easyCyte systems have optimized templates for acquisition and data analysis-which provide you with median fluorescent intensity (MFI) measurements for the determination of positive samples, and support semi-qualitative analysis, providing insight into antigen responses as shown by MFIs over time and/or between samples. Simple visual interpretation of results enables you to compare relative antibody levels.

This assay was also developed to support both single-sample and 96-well plate acquisition formats, meeting a range of throughput needs. Additionally, with just 15 minutes of hands-on time, results are ready in 75 minutes for rapid access to a comprehensive anti-SARS-CoV-2 antibody profile.

Vaccines vs. COVID-19-monitoring changes in the immune response over time

As labs continue to research vaccination strategies, the need to evaluate the persistence and magnitude of the antibody response across different sub-groups of the vaccinated population will continue to place emphasis on the information provided by anti-SARS-CoV-2 antibody profiles.

The Guava SARS-CoV-2 Multi-Antigen Antibody Kit can help deliver the information you need with fast results and flexible throughput. If you'd like to learn more about the kit, visit our website to download the sales sheet.

For Research Use Only. Not for use in diagnostic procedures.

Related Content
  • Guava® SARS-CoV-2 Multi-Antigen Antibody Kit [Flyer]
  • Flow Cytometry Applications for COVID-19 Research [Flyer]
  • Luminex Flow Cytometry and Imaging [Webpage]
  • AAI Research Poster [Download]
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Luminex Corporation published this content on 16 June 2021 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 16 June 2021 11:07:05 UTC.