Notes
|
Six months ended June 30,
2023
£'000
|
Six months ended June 30,
2022
£'000
| ||||||||||
Revenue
| 3 | 7,128 | - | |||||||||
Cost of revenue
| 3 | (2,455 | ) | 352 | ||||||||
Research and development expenses
| (7,898 | ) | (13,322 | ) | ||||||||
Administrative expenses
| (9,548 | ) | (8,840 | ) | ||||||||
Other operating income
| 3 | 2,864 | - | |||||||||
Operating loss
|
(9,909
| ) |
(21,810
|
)
| ||||||||
Finance income
| 4 | 550 | 173 | |||||||||
Finance costs
| 4 | (1,498 | ) | (1,859 | ) | |||||||
Changes in the fair value of financial instruments
| 4 | 365 | 1,210 | |||||||||
Net foreign exchange (loss)/gain
| (1,445 | ) | 1,582 | |||||||||
Other income
| 5 | - | 811 | |||||||||
Loss before tax
|
(11,937
| ) |
(19,893
|
)
| ||||||||
Taxation
| 907 | 735 | ||||||||||
Loss for the period, attributable to equity holders of the parent
|
(11,030
| ) |
(19,158
|
)
| ||||||||
Items that may be reclassified subsequently to profit or loss:
| ||||||||||||
Currency translation of foreign operations
| 1,493 | (1,775 | ) | |||||||||
Total comprehensive loss for the period, attributable to equity holders of the parent
|
(9,537
| ) |
(20,933
|
)
| ||||||||
Basic loss per share for the period (in £)
| 6 | (0.02 | ) | (0.03 | ) | |||||||
Diluted loss per share for the period (in £)
| 6 | (0.02 | ) | (0.03 | ) |
Notes
|
June 30,
2023
£'000
|
December 31, 2022
£'000
| ||||||||||
Assets
| ||||||||||||
Non-current
assets
| ||||||||||||
Property, plant and equipment
| 7 | 1,565 | 1,831 | |||||||||
Intangible assets
| 8 | 24,845 | 24,116 | |||||||||
26,410 | 25,947 | |||||||||||
Current assets
| ||||||||||||
Prepayments
| 1,376 | 3,125 | ||||||||||
R&D tax credits
| 2,203 | 1,296 | ||||||||||
Other taxes receivable
| 643 | 614 | ||||||||||
Trade and other receivables
| 3 | 7,893 | 762 | |||||||||
Cash and short-term deposits
| 42,113 | 56,334 | ||||||||||
54,228 | 62,131 | |||||||||||
Total assets
|
80,638
|
88,078
| ||||||||||
Equity and liabilities
| ||||||||||||
Non-current
liabilities
| ||||||||||||
Provisions
| 10 | 411 | - | |||||||||
Convertible loan notes
| 11 | 3,665 | - | |||||||||
Warrant liability
| 12 | 166 | 129 | |||||||||
Lease liability
| 973 | 1,222 | ||||||||||
Other liabilities
| 220 | 182 | ||||||||||
5,435
|
1,533
| |||||||||||
Current liabilities
| ||||||||||||
Trade and other payables
| 1,911 | 3,078 | ||||||||||
Accruals
| 4,786 | 4,491 | ||||||||||
Provisions
| 10 | 4,701 | 4,822 | |||||||||
Convertible loan notes
| 11 | 4,186 | 11,085 | |||||||||
Warrant liability
| 12 | - | 402 | |||||||||
Lease liability
| 488 | 466 | ||||||||||
Other liabilities
| 3 | 1,386 | 333 | |||||||||
17,458
|
24,677
| |||||||||||
Total liabilities
|
22,893
|
26,210
| ||||||||||
Net assets
|
57,745
|
61,868
| ||||||||||
Equity
| ||||||||||||
Issued capital
| 9 | 1,930 | 1,875 | |||||||||
Share premium
| 9 | 257,343 | 254,303 | |||||||||
Other capital reserves
| 9 | 134,999 | 132,680 | |||||||||
Employee Benefit Trust shares
| (1,058 | ) | (1,058 | ) | ||||||||
Other reserves
| 7,401 | 7,401 | ||||||||||
Accumulated losses
| (342,194 | ) | (331,164 | ) | ||||||||
Translation reserve
| (676 | ) | (2,169 | ) | ||||||||
Total equity
|
57,745
|
61,868
| ||||||||||
Notes
|
Six months ended June 30,
2023
£'000
|
Six months ended June 30,
2022
£'000
| ||||||||||
Operating activities
| ||||||||||||
Loss before tax
| (11,937 |
)
| (19,893 | ) | ||||||||
Adjustments to reconcile (loss)/profit to net cash flows:
| ||||||||||||
Depreciation and impairment of property, plant and equipment
| 7 | 266 | 436 | |||||||||
Amortization of intangible assets
| 8 | 138 | - | |||||||||
Share-based payment expense
| 9 | 1,931 | 2,446 | |||||||||
Net foreign exchange loss/(gain)
| 1,282 | (2,100 | ) | |||||||||
Increase in provisions and other liabilities
| 10,3 | 1,130 | 307 | |||||||||
Finance income
| 4 | (550 | ) | (173 | ) | |||||||
Finance costs
| 4 | 1,084 | 1,696 | |||||||||
Fair value remeasurement on warrants
| 4 | (365 | ) | (1,210 | ) | |||||||
Other income and expenses
| 5 | - | (811 | ) | ||||||||
Other
non-cash
movements
| 3 | 155 | 330 | |||||||||
Working capital adjustments
| ||||||||||||
(Increase)/decrease in receivables and prepayments
| (5,521 | ) | 331 | |||||||||
(Decrease)/increase in trade and other payables and accruals
| (846 | ) | 1,364 | |||||||||
Taxation
| (29 | ) | (1,529 | ) | ||||||||
Net cash flows used in operating activities
|
(13,262
| ) |
(18,806
|
)
| ||||||||
Investing activities
| ||||||||||||
Purchase of property, plant and equipment
| 7 | - | (10 | ) | ||||||||
Proceeds from intangible asset (net of transaction costs)
| 5 | - | 1,484 | |||||||||
Payments to CVR holders
| 5 | - | (673 | ) | ||||||||
Interest earned
| 4 | 468 | 173 | |||||||||
Payments to acquire intangible assets
| (337 | ) | - | |||||||||
Net cash flows from investing activities
|
131
|
974
| ||||||||||
Financing activities
| ||||||||||||
Proceeds from issuance of ordinary shares
| 2 | - | ||||||||||
Interest paid
| 4 | (771 | ) | - | ||||||||
Payment of lease liabilities
| (226 | ) | (445 | ) | ||||||||
Proceeds from TAP agreement
| 79 | 153 | ||||||||||
Net cash flows used in financing activities
|
(916
|
)
|
(292
|
)
| ||||||||
Net decrease in cash and cash equivalents
|
(14,047
|
)
|
(18,124
|
)
| ||||||||
Cash and cash equivalents at the beginning of the period
| 56,334 | 94,296 | ||||||||||
Effect of exchange rate changes on cash and cash equivalents
| (174 | ) | 243 | |||||||||
Cash and cash equivalents at the end of the period
|
42,113
|
76,415
| ||||||||||
Notes
|
Issued capital
£'000
|
Share premium
£'000
|
Other capital reserves
£'000
|
Employee Benefit Trust
£'000
|
Other reserves
£'000
|
Accumulated losses
£'000
|
Translation reserve
£'000
|
Total equity
£'000
| ||||||||||||||||||||||||||||
At December 31, 2021
|
1,755
|
247,460
|
129,835
|
(1,140
|
)
|
7,401
|
(296,968
|
)
|
(341
|
)
|
88,002
| |||||||||||||||||||||||||
Loss for the period
| - | - | - | - | - | (19,158 | ) | - | (19,158 | ) | ||||||||||||||||||||||||||
Other comprehensive loss
| - | - | - | - | - | - | (1,775 | ) | (1,775 | ) | ||||||||||||||||||||||||||
Total comprehensive loss
|
-
|
-
|
-
|
-
|
-
|
(19,158
|
)
|
(1,775
|
)
|
(20,933
|
)
| |||||||||||||||||||||||||
Share-based payments
| 9 | - | - | 2,446 | - | - | - | - | 2,446 | |||||||||||||||||||||||||||
Exercise of share options
| - | - | (82 | ) | 82 | - | - | - | - | |||||||||||||||||||||||||||
Issuance of warrants
| - | - | 70 | - | - | - | - | 70 | ||||||||||||||||||||||||||||
At June 30, 2022
|
1,755
|
247,460
|
132,269
|
(1,058
|
)
|
7,401
|
(316,126
|
)
|
(2,116
|
)
|
69,585
| |||||||||||||||||||||||||
At December 31, 2022
|
1,875
|
254,303
|
132,680
|
(1,058
|
)
|
7,401
|
(331,164
|
)
|
(2,169
|
)
|
61,868
| |||||||||||||||||||||||||
Loss for the period
| - | - | - | - | - | (11,030 | ) | - | (11,030 | ) | ||||||||||||||||||||||||||
Other comprehensive income
| - | - | - | - | - | - | 1,493 | 1,493 | ||||||||||||||||||||||||||||
Total comprehensive loss
|
-
|
-
|
-
|
-
|
-
|
(11,030
|
)
|
1,493
|
(9,537
|
)
| ||||||||||||||||||||||||||
Share-based payments
|
9
| - | - | 1,931 | - | - | - | - | 1,931 | |||||||||||||||||||||||||||
Exercise of share options
|
2 |
-
|
-
|
-
|
-
|
-
|
-
|
2 | ||||||||||||||||||||||||||||
Issuance of shares |
9
|
53 |
3,040 |
347 |
-
|
-
|
-
|
-
|
3,440 | |||||||||||||||||||||||||||
Issuance of warrants
| - | - | 41 | - | - | - | - | 41 | ||||||||||||||||||||||||||||
At June 30, 2023
|
1,930
|
257,343
|
134,999
|
(1,058
| ) |
7,401
|
(342,194
| ) |
(676
| ) |
57,745
| |||||||||||||||||||||||||
Six months
ended June 30,
2023
£'000
|
Six months
ended June 30,
2022
£'000
| |||||||
Interest income on short-term deposits
| 468 | 173 | ||||||
Modification of convertible loan notes
| 82 | - | ||||||
Total
|
550
|
173
| ||||||
Six months
ended June 30,
2023
£'000
|
Six months
ended June 30,
2022
£'000
| |||||||
Interest on convertible loan notes
| (1,004 | ) | (1,567 | ) | ||||
Interest on lease liabilities
| (79 | ) | (113 | ) | ||||
Discounting of provisions for deferred contingent cash consideration
| (395 | ) | (163 | ) | ||||
Other
| (20 | ) | (16 | ) | ||||
Total
|
(1,498
| ) |
(1,859
|
)
| ||||
Six months
ended June 30,
2023
£'000
|
Six months
ended June 30,
2022
£'000
| |||||||
Changes in the fair value of warrants - private placement
| 402 | 1,091 | ||||||
Changes in the fair value of warrants - bank loan
| (37 | ) | 119 | |||||
Total
|
365
|
1,210
| ||||||
Six months
ended June 30,
2023
£'000
|
Six months
ended June 30,
2022
£'000
| |||||||
Numerator - Basic loss per share (£'000)
| ||||||||
Loss attributable to equity holders of the parent
| (11,030 | ) | (19,158 | ) | ||||
Denominator - Basic loss per share
| ||||||||
Weighted average number of ordinary shares
| 627,087,752 | 583,892,445 | ||||||
Loss per share - basic (£)
| (0.02 | ) | (0.03 | ) | ||||
Numerator - Diluted loss per share (£'000):
| ||||||||
Loss attributable to equity holders of the parent
| (11,030 | ) | (19,158 | ) | ||||
Effect of dilutive ordinary shares
| - | - | ||||||
Numerator - Diluted loss per share
| (11,030 | ) | (19,158 | ) | ||||
Denominator - Diluted loss per share:
| ||||||||
Number of ordinary shares used for basic loss per share
| 627,087,752 | 583,892,445 | ||||||
Weighted average effect of dilutive ordinary shares
| - | - | ||||||
Weighted average number of diluted ordinary shares outstanding
| 627,087,752 | 583,892,445 | ||||||
Loss per share - diluted (£)
| (0.02 | ) | (0.03 | ) |
Right-of-use
asset (building) (£'000) |
Leasehold
improvements (£'000) |
Office Equipment (£'000) |
IT Equipment (£'000) |
Total (£'000) | ||||||||||||||||
Cost or valuation at January 1, 2023 and June 30, 2023
|
2,465
|
557
|
164
|
173
|
3,359
| |||||||||||||||
Depreciation and impairment
| ||||||||||||||||||||
At January 1, 2023
|
(1,088
|
)
|
(219
|
)
|
(76
|
)
|
(145
|
)
|
(1,528
|
)
| ||||||||||
Depreciation for the period
| (199 | ) | (48 | ) | (11 | ) | (9 | ) | (266 | ) | ||||||||||
At June 30, 2023
|
(1,287
|
)
|
(267
|
)
|
(87
|
)
|
(154
|
)
|
(1,794
|
)
| ||||||||||
Net book value
| ||||||||||||||||||||
At January 1, 2023
| 1,377 | 338 | 88 | 28 | 1,831 | |||||||||||||||
At June 30, 2023
|
1,178
|
290
|
77
|
19
|
1,565
| |||||||||||||||
Acquired development programs | ||||
Cost
| ||||
At January 1, 2023
|
33,005
| |||
Additions
| 1,166 | |||
At June 30, 2023
|
34,172
| |||
Accumulated revision to estimated value
| ||||
At January 1, 2023
| (8,889 | ) | ||
Revision to estimated value
| (300 | ) | ||
At June 30, 2023
| (9,189 | ) | ||
Accumulated amortization
| ||||
At January 1, 2023
| - | |||
Amortization for the period
| (138 | ) | ||
At June 30, 2023
| (138 | ) | ||
Net book value
| ||||
At January 1, 2023
| 24,116 | |||
At June 30, 2023
|
24,845
| |||
Number of ordinary shares |
Ordinary
Share
Capital
£'000
|
Share
Premium
£'000
| ||||||||||
At January 1, 2022 and June 30, 2022
| 584,908,239 | 1,755 | 247,460 | |||||||||
At January 1, 2023
|
624,928,519
|
1,875
|
254,303
| |||||||||
Issued during the period
| 18,276,275 | 55 | 3,040 | |||||||||
At June 30, 2023
| 643,204,794 | 1,930 | 257,343 | |||||||||
Share-based
payments £'000 |
Equity component of convertible loan
£'000
|
Other warrants issued
£'000
|
Merger reserve
£'000
|
Other reserve £'000 |
Total
£'000
| |||||||||||||||||||
At January 1, 2022
|
23,026
|
32,843
|
44
|
40,818
|
33,104
|
129,835
| ||||||||||||||||||
Share-based payments expense during the period
| 2,446 | - | - | - | - | 2,446 | ||||||||||||||||||
Share option exercise
| (82 | ) | - | - | - | - | (82 | ) | ||||||||||||||||
Issuance of warrants
| - | - | 70 | - | - | 70 | ||||||||||||||||||
At June 30, 2022
|
25,390
|
32,843
|
114
|
40,818
|
33,104
|
132,269
| ||||||||||||||||||
At January 1, 2023
|
26,806
|
31,838
|
114
|
40,818
|
33,104
|
132,680
| ||||||||||||||||||
Share-based payments expense during the period
| 1,931 | - | - | - | - | 1,931 | ||||||||||||||||||
Extinguishment and issuance of Novartis Loan Note
| - |
347
| - | - | - | 347 | ||||||||||||||||||
Issue of warrants
| - | - |
41
| - | - |
41
| ||||||||||||||||||
At June 30, 2023
|
28,737
|
32,185
|
155
|
40,818
|
33,104
|
134,999
| ||||||||||||||||||
Mereo 2019 Equity Incentive Plan
|
Mereo 2019 NED Equity Incentive Plan
| |||||||||||||||||||||||
Awards
(ADS)
|
Weighted average fair value
($) per share
|
Weighted average exercise price ($) per share |
Awards
(ADS)
|
Weighted average fair value
($) per share
|
Weighted average exercise price ($) per share | |||||||||||||||||||
Options
| 4,617,000 | 0.91 | 1.01 | 440,000 | 0.84 | 0.94 | ||||||||||||||||||
RSU's
| 617,750 | 1.01 | - | 479,813 | 0.94 | - | ||||||||||||||||||
PSU's
| 1,543,150 | 0.61 | - | - | - | - |
• |
Options over ADSs granted during the six months ended June 30, 2023, were valued using the Black-Scholes model with the following weighted average inputs: expected volatility of
98.06%; risk free interest rate of 3.43%; expected life of 10 years; and market price per ADS of $1.01.
|
• |
RSUs over ADSs granted during the six months ended June 30, 2023 vest over
three years with one third of the awards vesting after twelve months and the remainder vesting equally every six months thereafter. These awards were valued by reference to the value of the shares awarded.
|
•
|
PSUs over ADSs
granted during the six months ended June 30, 2023 will only vest upon achievement of specified stretching share price performance targets. These awards were valued using a Monte Carlo model with the following key inputs: expected volatility of 105.6%; expected life of between 0.9 and 1.1 years; risk free interest rate of 4.14% and market price per ADS of $1.01.
|
•
|
Options over ADSs granted under the Mereo 2019 NED Equity Incentive Plan to certain non-executive directors during the six months ended June 30, 2023 were valued using the Black-Scholes model with the following inputs: expected volatility of
97.94%; risk free interest rate of 3.36%; expected life of 10 years; and market price per ADS of $0.94.
|
•
|
Deferred RSU's over ADSs were granted during the six months ended June 30, 2023 under the Mereo 2019 NED Equity Incentive Plan to certain non-executive directors who elected to receive restricted stock units in lieu of their cash fees for the year commencing February 1, 2023. These awards were valued by reference to the value of the shares awarded.
|
June 30, 2023
£'000
|
December 31, 2022
£'000
| |||||||
Social security contribution on vested share options
|
56
|
9
| ||||||
Provisions for deferred contingent cash consideration
| 5,056 | 4,634 | ||||||
Restructuring
| - |
179
| ||||||
Total
|
5,112
|
4,822
| ||||||
Current
| 4,701 |
4,822
| ||||||
Non-Current
| 411 |
-
|
June 30,
2023
£'000
|
December 31, 2022
£'000
| |||||||
Novartis Loan Note
| 3,665 | 4,449 | ||||||
Loan Notes - Private Placement
|
4,186
|
6,636
| ||||||
Total
|
7,851
|
11,085
| ||||||
Current
| 4,186 | 11,085 | ||||||
Non-Current
| 3,665 | - |
June 30,
2023
£'000
|
June 30,
2022
£'000
| |||||||
At January 1
| 531 | 8,336 | ||||||
Fair Value changes during the period
| (365 | ) | (1,210 | ) | ||||
At June 30
| 166 | 7,126 | ||||||
June 30,
2023
£'000
|
December 31, 2022
£'000
| |||||||
Current
| - | 402 | ||||||
Non-current
| 166 | 129 | ||||||
Total
| 166 |
531
| ||||||
June 30,
2023
£'000
|
December 31, 2022
£'000
| |||||||
Expected volatility (%)
| 100 | 95 | ||||||
Risk-free interest rate (%)
| 3.45 | 3.99 | ||||||
Expected life of warrants (years)
| 4.70 | 0.5 | ||||||
Market price of ADS($)
| 1.32 | 0.75 | ||||||
Model used
| Black-Scholes |
Black-Scholes
|
Fair value
measured
using unadjusted quoted prices (Level 1) |
Fair value
measured
using significant
observable
inputs (Level 2)
|
Fair value
measured
using significant
unobservable
inputs (Level 3)
| ||||||||||
Warrant liabilities
| - | 166 | - | |||||||||
Provisions for deferred contingent cash consideration
| - | - | 5,056 | |||||||||
Total
| - | 166 | 5,056 | |||||||||
Provisions
for deferred
contingent cash
consideration £'000 |
Warrant liability
£'000
| |||||||
At January 1, 2023
|
4,634
|
402
| ||||||
Additions during the period
| 561 | - | ||||||
Revisions to estimate
| (300 | ) | - | |||||
Movement during the period
| 161 | (402 | ) | |||||
At June 30, 2023
|
5,056
|
-
| ||||||
Valuation technique
|
Significant unobservable inputs |
Input range
|
Sensitivity of the input to fair value
| |||||
Provision for AstraZeneca deferred contingent cash consideration |
Discounted cash flow | WACC | 2023: 15% |
1% increase/decrease would result in a decrease/increase in fair value by £
21,000
.
| ||||
WACC | 2022: 15% | 1% increase/decrease would result in a decrease/increase in fair value by £31,000. | ||||||
Probability of success |
2023: 40.6% - 81.2%
|
10% increase/decrease would result in an increase/decrease in fair value by £0.5 million. | ||||||
Probability of success | 2022: 40.6% - 81.2% | 10% increase/decrease would result in an increase/decrease in fair value by £0.5 million. |
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Disclaimer
Mereo BioPharma Group plc published this content on 07 September 2023 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 07 September 2023 11:40:06 UTC.