On March 21, 2023, the Board of Directors of Milestone Pharmaceuticals Inc., upon the recommendation of the Nominating & Corporate Governance Committee of the Board, voted to elect Seth H.Z. Fischer to the Board, effective as of March 21, 2023. Mr. Fischer's term as director will expire at the Company's 2023 annual meeting of stockholders. Mr. Fischer brings to the Board over 40 years of experience in the pharmaceutical and medical device industry, including 29 years in various leadership roles at Johnson & Johnson.

Mr. Fischer currently serves as a member of the Board of Directors of Agile Therapeutics Inc. (AGRX), Marinus Pharmaceuticals Inc. (MRNS), Spectrum Pharmaceuticals Inc. (SPPI), and Esperion Therapeutics Inc. (ESPR). Previously, Mr. Fischer served as the Chief Executive Officer and as a Director of Vivus Inc., a publicly traded company, from September 2013 to December 2017. From May 2013 to May 2019, Mr. Fischer also served on the Board of Directors of BioSig Technologies Inc. Mr. Fischer earned a bachelor's degree in general studies from Ohio University and served as a captain in the U.S. Air Force.