On September 2, 2021, Dr. Jay B. Saoud tendered his resignation, effective September 15, 2021, as the Senior Vice President, Head of Research and Development of Minerva Neurosciences, Inc. Dr. Saoud was a named executive officer of the company for the year ended December 31, 2020. In connection with Dr. Saoud’s resignation, the company and Dr. Saoud entered into a Transition, Separation, and Consulting Agreement, dated September 2, 2021. Under the terms of the Agreement, upon Dr. Saoud’s termination of employment with the company, he will continue providing services as a consultant to the company from September 15, 2021 through June 30, 2022, subject to earlier termination by either Dr. Saoud or the company upon 30 days’ notice, or by the company upon Dr. Saoud’s material breach of the terms thereof.