On May 3, 2023, William Doyle notified the Board of Directors of Minerva Neurosciences, Inc. of his intention to resign as a member of the Board, effective May 3, 2023, including from his role as Chair of the Compensation Committee of the Board and a member of the Audit Committee of the Board. Mr. Doyle is resigning to focus on other opportunities and his decision did not involve any disagreement with the Company, its management or the Board. Following Mr. Doyle's resignation, the Board, upon the recommendation of the Nominating and Corporate Governance Committee of the Board, appointed Fouzia Laghrissi-Thode, M.D., who currently serves as a member of the Compensation Committee, as the new Chair of the Compensation Committee and Hans Peter Hasler, a current director on the Board, as a new member of the Audit Committee, each effective May 3, 2023.