Mitsubishi Tanabe Pharma America Inc. announced that EXSERVAN™ (riluzole), the first oral film formulation of riluzole, is now available in the U.S. for the treatment of amyotrophic lateral sclerosis (ALS). EXSERVAN, which dissolves on top of the tongue, was developed to help meet the needs of people with ALS, including those who have difficulty swallowing some medications. The U.S. Food and Drug Administration (FDA) approved EXSERVAN in November 2019 based on a pivotal bioavailability and bioequivalence study to bridge the safety and efficacy of the new oral film formulation to the approved tablet dosage form of riluzole. EXSERVAN was shown to deliver a similar amount of medication throughout the bloodstream as the riluzole tablets. Riluzole was approved by the FDA in 1995 for the treatment of ALS and showed that the time to tracheostomy or death was longer for patients receiving riluzole tablets compared to placebo. EXSERVAN oral film (50 mg each) dissolves on the top of the tongue and is taken twice a day without liquids or food. The treatment should be taken at least one hour before or two hours after a meal. Patients and caregivers should carefully read the "Instructions for Use" on how to properly take EXSERVAN oral film. Access to EXSERVAN is available through a single specialty pharmacy, PANTHERx Rare Pharmacy. Treatment with the medication is initiated by a healthcare provider (HCP) by submitting a Prescription and Enrollment Form to PANTHERx. Patients are then contacted by the specialty pharmacy to review insurance benefits and product dispensing. PANTHERx also is able to enroll eligible patients in the EXSERVAN Out-of-Pocket Assistance Program. PANTHERx can be contacted at 1-855-743-9275. Patients prescribed EXSERVAN through the Department of Veterans Affairs, the Department of Defense, other federal institutions and certain integrated delivery networks do not need to coordinate via PANTHERx, they should obtain the therapy through their healthcare providers as with their other medications.