On August 11, 2022, Monica Bertagnolli notified the Board of Directors (the Board") of Natera, Inc. of her intention to resign as a member of the Board and any committees of the Board, effective August 12, 2022, in connection with her appointment as Director of the National Cancer Institute. Ms. Bertagnolli's resignation was not a result of any disagreement with the Company on any matter relating to its operations, policies or practices.