Item 8.01 Other Events.

On December 1, 2021, FS Development Corp. II, a Delaware corporation (the "Company"), issued a press release announcing that its registration statement on Form S-4 (File No. 333-258442) (as amended, the "Registration Statement"), relating to the previously announced business combination (the "Business Combination") with Pardes Biosciences, Inc. ("Pardes"), had been declared effective by the U.S. Securities and Exchange Commission ("SEC"). In the Registration Statement, the conversion ratio (the "Conversion Ratio") for determining the number of shares of the Company's Class A Common Stock to be issued as consideration (the "Merger Consideration") to the holders of Pardes' outstanding equity in connection with the closing of the Business Combination was calculated as of November 3, 2021. The Special Meeting of the Company's stockholders to approve the Business Combination and other matters related thereto is scheduled for 9:00 a.m. (Eastern time) on December 23, 2021 (the "Special Meeting).

The Conversion Ratio calculated as of December 16, 2021, which is expected to be the Conversion Ratio used for calculating the final Merger Consideration, is 1.4078, meaning that of the 32.5 million shares of the Company's Class A Common Stock being issued as the Merger Consideration, 29,364,235 shares will be issued for all issued and outstanding Pardes common stock and preferred stock, 2,878,138 shares will be reserved for issuance under the 2021 Stock Option and Incentive Plan for Pardes's outstanding vested, unvested, and unexercised options and 257,627 shares will be reserved for issuance under the 2021 Stock Option and Incentive Plan for outstanding contractual commitments to grant equity awards to persons following the closing of the Business Combination.

Important Information About the Business Combination and Where to Find It

In connection with the merger agreement, dated June 29, 2021, entered into by and among the Company, Orchard Merger Sub, Inc., Pardes and Shareholder Representative Services LLC in connection with the Business Combination (as amended, the "Merger Agreement"), the Company has filed with the SEC a registration statement on Form S-4, which includes a description of the terms of the business and includes a prospectus with respect to the combined company's securities to be issued in connection with the Business Combination and a proxy statement with respect to the shareholder meeting of the Company to vote on the Business Combination. Before making a voting decision, investors, shareholders and other interested persons of the Company are urged to read the preliminary proxy statement/prospectus as well as other documents filed with the SEC because these documents will contain important information about the Company, Pardes and the Business Combination. The definitive proxy statement/prospectus included in the registration statement is being mailed to shareholders of the Company of record as of the Record Date. Once available, shareholders will also be able to obtain a copy of the Form S-4, including the proxy statement/prospectus, and other documents filed with the SEC without charge, by directing a request to: FS Development Corp. II, Attn: Secretary, 900 Larkspur Landing Circle, Suite 150, Larkspur, California 94939. The preliminary and definitive proxy statement/prospectus included in the registration statement can also be obtained, without charge, at the SEC's website (www.sec.gov).

Participants in the Solicitation

The Company and Pardes and their respective directors and executive officers may be considered participants in the solicitation of proxies with respect to the proposed business combination described in this Current Report under the rules of the SEC. Information about the directors and executive officers of the Company is set forth in the filed registration statement on Form S-4 containing the proxy statement/prospectus for the proposed business combination, and is available free of charge at the SEC's website at www.sec.gov or by directing a request to: FS Development Corp. II, Attn: Secretary, 900 Larkspur Landing Circle, Suite 150, Larkspur, California 94939.





No Offer or Solicitation

This Current Report on Form 8-K is not a proxy statement or solicitation of a proxy, consent or authorization with respect to any securities or in respect of the proposed Business Combination and shall not constitute an offer to sell or a solicitation of an offer to buy any securities, nor shall there be any sale of securities in any state or jurisdiction in which such offer, solicitation, or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction. No offer of securities shall be made except by means of a prospectus meeting the requirements of the Securities Act of 1933, as amended.

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