Prothena Corporation plc provides earnings guidance for the full year 2020. The Company continues to expect its full year 2020 net cash burn from operating and investing activities to be $75-$85 million and expects to end the year with approximately $299 million in cash, cash equivalents and restricted cash (midpoint). The estimated full year 2020 net cash burn from operating and investing activities is primarily driven by estimated net loss of $101-$118 million, which includes an estimated $23 million of non-cash share-based compensation expense.