Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On April 5, 2023, Sio Gene Therapies Inc. (the "Company") held a special meeting of its stockholders (the "Special Meeting") to vote on the three proposals described in detail in the Company's definitive proxy statement filed with the U.S. Securities and Exchange Commission on February 21, 2023 and mailed to the Company's stockholders on or about such date (the "Proxy Statement"). Effective upon the approval by the Company's stockholders of the liquidation and dissolution of the Company (the "Dissolution") pursuant to the Plan of Complete Liquidation and Dissolution (the "Plan of Dissolution"), which authorizes the Company to liquidate and dissolve the Company in accordance with the Plan of Dissolution, each of the directors of the Company other than David Nassif, the Company's Chief Executive Officer, Chief Financial Officer, Chief Accounting Officer, and General Counsel, resigned in connection with the Company's dissolution. No disagreement exists between the Company and any such director on any matter relating to the Company's operations, policies or practices.

Item 5.07 Submission of Matters to a Vote of Security Holders.

As disclosed in the Proxy Statement, as of the close of business on February 14, 2023, the record date for the Special Meeting, there were 73,975,196 shares of the Company's common stock outstanding and entitled to vote at the Special Meeting. A total of 46,470,274 shares of the Company's common stock, representing approximately 62.82% of the shares outstanding and entitled to vote and constituting a quorum, were represented in person (virtually) or by valid proxies at the Special Meeting.

The final voting results for each of the proposals submitted to a vote of stockholders at the Special Meeting are as follows:

Proposal 1 - Approval of the Plan of Dissolution

The Company's stockholders approved the Dissolution of the Company pursuant to the Plan of Dissolution, which authorizes the Company to liquidate and dissolve the Company in accordance with the Plan of Dissolution. The voting results are set forth in the table immediately below:



For                Against       Abstained
  46,030,603        393,418       46,253

Proposal 2 - Non-binding Advisory Vote on Compensation of Named Executive Officer

The Company's stockholders approved, on an advisory (non-binding) basis, the compensation of the Company's named executive officer that is based on or otherwise relates to the Dissolution. The voting results are set forth in the table immediately below:



For                Against         Abstained
  37,339,315        8,947,847       183,112

Proposal 3 - Adjournment of the Special Meeting, if necessary or appropriate

In connection with the Special Meeting, the Company also solicited proxies with respect to any proposal to adjourn the Special Meeting to a later date or dates, if necessary or appropriate, including to solicit additional proxies to approve the dissolution and liquidation of the Company pursuant to the Plan of Dissolution if there are insufficient votes to approve the dissolution and liquidation of the Company pursuant to the Plan of Dissolution at the time of the Special Meeting. Because there were sufficient votes represented at the time of the Special Meeting to approve the dissolution and liquidation of the Company pursuant to the Plan of Dissolution, the proposal to approve one or more adjournments of the Special Meeting was moot and was not presented for approval by the Company's stockholders at the Special Meeting.

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