Certain Common Stock of Tsubota Laboratory Incorporated are subject to a Lock-Up Agreement Ending on 19-DEC-2022. These Common Stock will be under lockup for 179 days starting from 23-JUN-2022 to 19-DEC-2022.

Details:
The lead managing underwriter during the period from the listing (start of trading) date to December 19, 2022, which is the 180th day from the date of conclusion of the principal underwriting contract for the sale of the shares by the underwriter and the underwriter. Issuance, transfer or sale of the Company's common stock (including potential shares and securities entitled to acquire the Company's common stock) held at its own expense on the date of conclusion of the principal underwriting contract without the prior written consent.

The Keio Innovation Initiative No. 1 Investment Business Limited Liability Union, which is a shareholder of the Company, begins on the date of concluding the principal underwriting agreement for the lead underwriter and the underwriting of the underwriter, and the date of listing (start of trading). During the period from September 20, 2022, which is the 90th day from the above, the Company's common stock held by its own calculation on the date of conclusion of the principal underwriting contract without obtaining the prior written consent of the lead managing underwriter.