Item 7.01 Regulation FD Disclosure

On August 3, 2020, Neoleukin Therapeutics, Inc., "Neoleukin" submitted a manuscript to bioRxiv, titled "De novo design of ACE2 protein decoys to neutralize SARS-CoV-2". BioRxiv is an online archive for unpublished preprints in the life sciences. The manuscript details the creation of a de novo protein decoy that binds to the SARS-CoV-2 spike protein and neutralizes viral infection of mammalian cells in vitro. The research was conducted by Neoleukin scientists and colleagues at the University of Hong Kong, University of Washington and University of North Carolina at Chapel Hill. The manuscript is currently undergoing peer review. Once posted, the manuscript will be available at bioRxiv.org.

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