Effective on December 17, 2023, Donald A. McGovern, Jr., resigned as a member of the Board of Directors of 180 Life Sciences Corp. (the ? Company?).

Mr. McGovern?s resignation was due to health reasons. Mr. McGovern?s resignation was not in connection with a disagreement with the Company on any matter relating to the Company?s operations, policies or practices. Mr. McGovern had served as the Lead Independent Director, Audit Committee Chairman, Compensation Committee Member, and Risk, Safety, Regulatory Committee Member prior to his resignation.