Adaptive Biotechnologies : Reports Second Quarter 2021 Financial Results (Form 8-K)

Adaptive Biotechnologies Reports Second Quarter 2021 Financial Results

SEATTLE, Aug. 4, 2021 (GLOBE NEWSWIRE) - Adaptive Biotechnologies Corporation ('Adaptive Biotechnologies') (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease, today reported financial results for the quarter ended June 30, 2021.

'We had another strong quarter with 83% revenue growth over prior year,' said Chad Robins, chief executive officer and co-founder of Adaptive Biotechnologies. 'I am encouraged by our performance across the business and excited about the emerging data from our immune medicine platform, which we expect to monetize for multiple opportunities in research, diagnostics and drug discovery.'

Recent Highlights

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Revenue of $38.5 million for the second quarter 2021, representing an 83% increase from the second quarter 2020

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clonoSEQ clinical sequencing volume in the second quarter 2021 grew 75% versus prior year and 15% over the first quarter of 2021

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Signed a license agreement with Vaccibody to leverage Adaptive Biotechnologies' T-cell data to inform the development of a T-cell based SARS-CoV-2 vaccine

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Signed an agreement with Moderna to use immunoSEQ T-MAP COVID to measure the T-cell response to their second generation COVID vaccine and their Zika vaccine

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Published case control data in Lyme disease and completing enrollment in ImmuneSense study to enable T-Detect Lyme offering in our CLIA certified lab around year end

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Advanced T-Detect pipeline in autoimmune diseases including Crohn's and Ulcerative Colitis for IBD differential diagnosis, and generated new early signal in Multiple Sclerosis

Second Quarter 2021 Financial Results

Revenue was $38.5 million for the quarter ended June 30, 2021, representing an 83% increase from the second quarter in the prior year. Sequencing revenue was $18.6million for the quarter, representing a 132% increase from the second quarter in the prior year. Development revenue was $20.0million for the quarter, representing a 53% increase from the second quarter in the prior year.

Operating expenses were $88.3 million for the second quarter of 2021, compared to $57.9 million in the second quarter of the prior year, representing an increase of 53%.

Net loss was $49.3 million for the second quarter of 2021, compared to $33.5 million for the same period in 2020.

Adjusted EBITDA (non-GAAP) was a loss of $35.6 million for the second quarter of 2021, compared to a loss of $28.5 million for the second quarter of the prior year.

Cash, cash equivalents and marketable securities was $689.5 million as of June 30, 2021.

2021 Financial Guidance

Adaptive Biotechnologies expects full year 2021 revenue to be in the range of $148 million to $155 million, representing 54% growth at the mid-point of the range over full year 2020 revenue. This compares to Adaptive Biotechnologies' previous outlook of $145 million to $155 million.

Webcast and Conference Call Information

Adaptive Biotechnologies will host a conference call to discuss its second quarter 2021 financial results after market close on Wednesday, August 4, 2021 at 4:30 PM Eastern Time. The conference call can be accessed at http://investors.adaptivebiotech.com. The webcast will be archived and available for replay at least 90 days after the event.

About Adaptive Biotechnologies

Adaptive Biotechnologies ('we' or 'our') is a commercial-stage biotechnology company focused on harnessing the inherent biology of the adaptive immune system to transform the diagnosis and treatment of disease. We believe the adaptive immune system is nature's most finely tuned diagnostic and therapeutic for most diseases, but the inability to decode it has prevented the medical community from fully leveraging its capabilities. Our proprietary immune medicine platform reveals and translates the massive genetics of the adaptive immune system with scale, precision and speed to develop products in life sciences research, clinical diagnostics and drug discovery. We have three commercial products and a robust clinical pipeline to diagnose, monitor and enable the treatment of diseases such as cancer, autoimmune conditions and infectious diseases. Our goal is to develop and commercialize immune-driven clinical products tailored to each individual patient.

Forward-Looking Statements

This press release contains forward-looking statements that are based on management's beliefs and assumptions and on information currently available to management. All statements contained in this release other than statements of historical fact are forward-looking statements, including statements regarding our ability to develop, commercialize and achieve market acceptance of our current and planned products and services, our research and development efforts and other matters regarding our business strategies, use of capital, results of operations and financial position and plans and objectives for future operations.

In some cases, you can identify forward-looking statements by the words 'may,' 'will,' 'could,' 'would,' 'should,' 'expect,' 'intend,' 'plan,' 'anticipate,' 'believe,' 'estimate,' 'predict,' 'project,' 'potential,' 'continue,' 'ongoing' or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words. These statements involve risks, uncertainties and other factors that may cause actual results, levels of activity, performance or achievements to be materially different from the information expressed or implied by these forward-looking statements. These risks, uncertainties and other factors are described under 'Risk Factors,' 'Management's Discussion and Analysis of Financial Condition and Results of Operations' and elsewhere in the documents we file with the Securities and Exchange Commission from time to time. We caution you that forward-looking statements are based on a combination of facts and factors currently known by us and our projections of the future, about which we cannot be certain. As a result, the forward-looking statements may not prove to be accurate. The forward-looking statements in this press release represent our views as of the date hereof. We undertake no obligation to update any forward-looking statements for any reason, except as required by law.

Use of Non-GAAP Financial Measure

To supplement our unaudited condensed consolidated statements of operations and unaudited condensed consolidated balance sheets, which are prepared in conformity with generally accepted accounting principles in the United States of America ('GAAP'), this press release also includes references to Adjusted EBITDA, which is a non-GAAP financial measure that we define as net loss adjusted for interest and other income, net, income tax benefit (expense), depreciation and amortization and share-based compensation expenses. We have provided a reconciliation of net loss, the most directly comparable GAAP financial measure, to Adjusted EBITDA at the end of this press release.

Management uses Adjusted EBITDA to evaluate the financial performance of our business and the effectiveness of our business strategies. We present Adjusted EBITDA because we believe it is frequently used by analysts, investors and other interested parties to evaluate companies in our industry and it facilitates comparisons on a consistent basis across reporting periods. Further, we believe it is helpful in highlighting trends in our operating results because it excludes items that are not indicative of our core operating performance.

Adjusted EBITDA has limitations as an analytical tool and you should not consider it in isolation or as a substitute for analysis of our results as reported under GAAP. We may in the future incur expenses similar to the adjustments in the presentation of Adjusted EBITDA. In particular, we expect to incur meaningful share-based compensation expense in the future. Other limitations include that Adjusted EBITDA does not reflect:

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all expenditures or future requirements for capital expenditures or contractual commitments;

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changes in our working capital needs;

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income tax benefit (expense), which may be a necessary element of our costs and ability to operate;

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the costs of replacing the assets being depreciated and amortized, which will often have to be replaced in the future;

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the non-cash component of employee compensation expense; and

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the impact of earnings or charges resulting from matters we consider not to be reflective, on a recurring basis, of our ongoing operations.

In addition, Adjusted EBITDA may not be comparable to similarly titled measures used by other companies in our industry or across different industries.

ADAPTIVE MEDIA
Beth Keshishian
917-912-7195
[e-mail]

ADAPTIVE INVESTORS
Karina Calzadilla, Vice President, Investor Relations

201-396-1687
Carrie Mendivil, Gilmartin Group
[e-mail]

Adaptive Biotechnologies

Condensed Consolidated Statements of Operations

(in thousands, except share and per share amounts)

(unaudited)

		Three Months Ended June 30,			Six Months Ended June 30,
		2021			2020			2021			2020
Revenue
Sequencing revenue		$	18,555			$	7,985			$	33,729			$	17,454
Development revenue			19,950				13,003				43,218				24,444
Total revenue			38,505				20,988				76,947				41,898
Operating expenses
Cost of revenue			10,765				4,912				20,756				10,255
Research and development			37,800				25,992				71,572				49,927
Sales and marketing			23,216				14,332				43,820				28,339
General and administrative			16,066				12,238				31,002				24,059
Amortization of intangible assets			423				423				842				847
Total operating expenses			88,270				57,897				167,992				113,427
Loss from operations			(49,765	)			(36,909	)			(91,045	)			(71,529	)
Interest and other income, net			464				1,893				1,102				4,787
Income tax benefit			-				1,481				-				1,804
Net loss		$	(49,301	)		$	(33,535	)		$	(89,943	)		$	(64,938	)
Net loss per share attributable to common shareholders, basic and diluted		$	(0.35	)		$	(0.26	)		$	(0.64	)		$	(0.51	)
Weighted-average shares used in computing net loss per share attributable to common shareholders, basic and diluted			140,359,317				127,383,582				139,667,380				126,720,986

Adaptive Biotechnologies

Condensed Consolidated Balance Sheets
(in thousands, except share and per share amounts)

		June 30, 2021			December 31, 2020
		(unaudited)
Assets
Current assets
Cash and cash equivalents		$	184,186			$	123,436
Short-term marketable securities (amortized cost of $413,965 and $564,036, respectively)			414,227				564,833
Accounts receivable, net			14,174				10,047
Inventory			18,612				14,063
Prepaid expenses and other current assets			12,530				14,535
Total current assets			643,729				726,914
Long-term assets
Property and equipment, net			75,235				39,692
Operating lease right-of-use assets			92,067				99,350
Long-term marketable securities (amortized cost of $91,177 and $118,429, respectively)			91,131				118,525
Restricted cash			2,138				2,138
Intangible assets, net			9,383				10,225
Goodwill			118,972				118,972
Other assets			719				598
Total assets		$	1,033,374			$	1,116,414
Liabilities and shareholders' equity
Current liabilities
Accounts payable		$	6,093			$	3,237
Accrued liabilities			13,539				13,162
Accrued compensation and benefits			8,630				11,950
Current portion of operating lease liabilities			4,833				3,529
Current portion of deferred revenue			83,553				73,319
Total current liabilities			116,648				105,197
Long-term liabilities
Operating lease liabilities, less current portion			103,774				104,333
Deferred revenue, less current portion			119,642				163,618
Total liabilities			340,064				373,148
Commitments and contingencies
Shareholders' equity
Preferred stock: $0.0001 par value, 10,000,000 shares authorized at June 30, 2021 and December 31, 2020; no shares issued and outstanding at June 30, 2021 and December 31, 2020			-				-
Common stock: $0.0001 par value, 340,000,000 shares authorized at June 30, 2021 and December 31, 2020; 140,663,755 and 137,646,896 shares issued and outstanding at June 30, 2021 and December 31, 2020, respectively			14				14
Additional paid-in capital			1,294,506				1,253,971
Accumulated other comprehensive gain			216				893
Accumulated deficit			(601,555	)			(511,612	)
Total Adaptive Biotechnologies Corporation shareholders' equity			693,181				743,266
Noncontrolling interest			129				-
Total shareholders' equity			693,310				743,266
Total liabilities and shareholders' equity		$	1,033,374			$	1,116,414

Adjusted EBITDA

The following table sets forth a reconciliation between our Adjusted EBITDA and our net loss, the most directly comparable GAAP financial measure, for each of the periods presented (in thousands, unaudited):

		Three Months Ended June 30,			Six Months Ended June 30,
		2021			2020			2021			2020
Net loss		$	(49,301	)		$	(33,535	)		$	(89,943	)		$	(64,938	)
Interest and other income, net			(464	)			(1,893	)			(1,102	)			(4,787	)
Income tax benefit			-				(1,481	)			-				(1,804	)
Depreciation and amortization expense			2,905				1,998				5,576				3,976
Share-based compensation expense			11,249				6,373				19,733				11,048
Adjusted EBITDA		$	(35,611	)		$	(28,538	)		$	(65,736	)		$	(56,505	)