Alar Pharmaceuticals Inc. announced positive interim results from the single-ascending-dose study of ALA-1000. A 3-month buprenorphine released injectable designed to be dosed subcdutaneously for treating opioid use disorder (OUD). The Buprenorphine release from the ALA-1000 single injection lasts over 12 weeks with effective concentrations, showing low initial burst without dose dumping effect and good safety and tolerability, including local skin irritation and injection pain severity. The world-wide opioid epidemic is a documented public health crisis. Treatments for opioid abuse currently rely on Buprenorphine, Methadone, and Naltrexone as Medication-assisted treatment (MAT). However, patients' need to make frequent trips to clinics for oral MAT treatment often leads to relapses or further substance abuse through the switching of one habit for another. While the industry continues to provide improved public awareness in workplaces, emergency departments, and the correctional system, more needs to be done to solve recurring opioid and opioid treatment abuse. The development of LAIs is considered an effective way to meet patients' needs and reduce opioid dependency.