Alpha Tau Medical Ltd. announced that its first patient with advanced inoperable pancreatic cancer has been treated in a feasibility and safety study of Alpha DaRT at the Jewish General Hospital ("JGH") in Montreal, Canada, which is an affiliated teaching hospital of McGill University, Faculty of Medicine. The trial seeks to recruit 30 participants who have Stage II, III, or IV pancreatic cancer and who have a pancreatic cancer which is deemed inoperable due to non-resectability, metastasis, or lack of fitness for surgery. The study will primarily examine the safety and feasibility of placing the Alpha DaRT sources in the tumor utilizing endoscopic ultrasound, and the overall safety of the procedure by measuring adverse events.

In addition, the study will examine the efficacy of Alpha DaRT in terms of metrics such as overall response rate, overall survival and change in blood levels of CA19-9 (a blood-based biomarker often correlated with metrics such as disease progression).