Annovis Bio, Inc. entered into a securities purchase agreement with an institutional investor for issuance of 114,911 common shares at a price of $8.92 per share for aggregate gross proceeds of $1,025,006.12 on March 15, 2024. The parties anticipate that the closing will occur as soon as possible after the satisfaction of all of the conditions to closing including, without limitation, the listing of the common shares on the NYSE.