aTyr Pharma, Inc. announced plans to initiate an Individual Patient Expanded Access Program (EAP) for its lead therapeutic candidate, efzofitimod, for patients with pulmonary sarcoidosis. The Individual Patient EAP is intended to allow access for patients who complete the Phase 3 EFZO-FIT?? study and wish to receive treatment with efzofitimOD outside of the clinical trial.

EAPs are designed to provide access to potential therapies before they are approved by the U.S. Food and Drug Administration (FDA). sometimes called "compassionate use," Expanded Access is a pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic or medical device) for treatment outside of clinical trials when no satisfactory alternative therapy options are available. By implementing the EAP, the Company does not anticipate any risk to its efzofitimomod drug supply, which it believes to be adequate for its two ongoing clinical trials, or expect a significant impact to its financial resources.

The administration of efzofitIMod as part of the Individual Patient EAP will occur independent of the EFZO-FITtm study protocol, and the Company, PIs and patients will remain blinded to the treatment that occurred as part of the EFZO- FIT?? study. Secondary endpoints include measures of lung function and sarcoidosis symptoms.