Item 5.07 Submission of Matters to a Vote of Security Holders.

(a)The Company held the 2022 Meeting virtually on May 17, 2022.

(b)The following proposals were voted upon at the 2022 Meeting and the final voting results with respect to each such proposal are set forth below:



Proposal 1: Based upon the following votes, the shareholders elected Dr. George
Milne, Mr. Peter Greenleaf, Dr. David R.W. Jayne, Mr. Joseph P. Hagan, Dr.
Daniel Billen, Mr. R. Hector MacKay-Dunn, Ms. Jill Leversage, Mr. Timothy P.
Walbert and Dr. Brinda Balakrishnan to serve as members of the Company's board
of directors until the annual general meeting of shareholders to be held in
2023.

          Nominee                    For            Withheld        Broker Non-Votes
Dr. George Milne                  26,713,176       17,437,781          27,895,212
Mr. Peter Greenleaf               31,700,200       12,450,757          27,895,212
Dr. David R.W. Jayne              33,300,962       10,859,995          27,895,212
Mr. Joseph P. Hagan               24,070,897       20,080,060          27,895,212
Dr. Daniel Billen                 33,482,518       10,668,439          27,895,212
Mr. R. Hector MacKay-Dunn         26,206,913       17,944,044          27,895,212
Ms. Jill Leversage                27,594,235       16,556,722          27,895,212
Mr. Timothy P. Walbert            33,368,946       10,782,011          27,895,212
Dr. Brinda Balakrishnan           34,251,064       9,899,893           27,895,212

Proposal 2: Based upon the following votes, the shareholders approved the appointment of PricewaterhouseCoopers LLP, Chartered Professional Accountants, as the Company's independent registered public accounting firm until the annual general meeting of shareholders to be held in 2023 or until a successor is appointed.



     For            Against        Abstain
  63,341,990       6,693,240      2,000,938

Proposal 3: Based upon the following votes, the shareholders approved, on a non-binding advisory basis, a "say on pay" resolution regarding the Company's executive compensation.



     For            Against         Abstain        Broker Non-Votes
  33,050,501       10,490,227       610,231           27,895,210

Item 9.01 Financial Statements and Exhibits




(d) Exhibits.
Exhibit No.           Description

                      Cover Page Interactive Data File (the cover page XBRL tags are embedded within
104                   the Inline XBRL document)

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