On November 1, 2023, in connection with the Assignment, Torben Straight Nissen, Ph.D., Michael Rosenblatt, M.D., William D. ?Chip? Baird, Gary P. Pisano, Ph.D., Cristina M. Rondinone, Ph.D., Paul J. Sekhri, William R. Hinshaw, Jr., Martin Hendrix, Robert Rosiello and Catherine Angell Sohn, Pharm.D. each notified Axcella Health Inc. of their respective resignations as members of the Company?s board of directors (the ?Board?) and all committees thereof, effective immediately. None of these resignations resulted from any disagreement with the Company on any matter relating to the Company?s operations, policies or practices.

Termination of Officers: On November 1, 2023, in connection with the Assignment (as defined below), William R.?Hinshaw, Jr. and Paul Fehlner were each notified by the Company of termination of their positions as President and Senior Vice President, Chief Legal Officer and Corporate Secretary, respectively, effective on November 1, 2023. Election of Director and Officer: On November 1, 2023, the Board appointed Craig R. Jalbert, age 61, as the Company?s President, Treasurer, Corporate Secretary, effective on November 2, 2023, and sole member of the Board, effective immediately. Mr. Jalbert will also serve as the Company?s principal accounting officer.

Mr. Jalbert?s term as director shall expire upon the election and qualification of his successor. Mr. Jalbert has not been appointed to any committee of the Board and as of the date hereof is not expected to be appointed to any committee of the Board. Mr. Jalbert has served as a principal of the Foxborough, Massachusetts accounting firm of Verdolino & Lowey, P.C. since 1987.

For over 30 years he has focused his practice in distressed businesses and has served, and continues to serve, in the capacities of officer and director for numerous firms in their wind-down phases.