BioRestorative Therapies, Inc. announced that the Japanese Patent and Trademark Office has issued a notice of allowance for a patent application related to the Company's metabolic ThermoStem program. The notice of allowance was issued on May 8, 2023. Upon issuance, this will be the fourth patent granted in Japan for the ThermoStem program.

Claims granted under the new Japanese patent will cover implantable three-dimensional scaffolds and brown adipocytes that have been derived from human brown adipose (fat)-derived stem cells. Therapeutic benefits of using brown adipose have been demonstrated in various models and may provide a valuable therapeutic tool for treating a range of metabolic disorders.