Berkeley Lights’ participation this year includes a new, recently accepted poster presentation as well as two podium presentations. The Company will also feature its Beacon® platform technology and workflows in booth #514 for attendees to explore with hands-on demonstrations.
Additional information on Berkeley Lights’ presentations is below:
- Poster presentation P021: A Rapid High-Throughput Workflow for TCR Discovery on Solid Tumors with Functional Verification
Abstract:Berkeley Lights will share new data on how the Berkeley Lights’ platform with Opto™ Cell Therapy Development Workflow allows for a multi-optics approach to study live, single T cells in culture. This technology paired with the workflow permits cells to stay alive, while probing protein production, cell-cell interactions, cytotoxicity, cell proliferation and downstream genomics analysis at the single cell level. - Podium presentation: High-Throughput Visualization of Cell-Cell Interactions for Therapeutic Development Using the Berkeley Lights Platform on
Tuesday, May 3, 2022 at10 a.m. ET .
Abstract: Berkeley Lights’ optofluidic platforms enable deterministic isolation and culturing of single or multiple cells in nanoliter-sized chambers, allowing for sequential functional assays on the same cell sample, thereby linking cytotoxicity and cytokine secretion. The Berkeley Lights R&D team recently demonstrated organoid structure formation on chip and is looking to use this capability in tumor microenvironment research.
Podium presentation: Leave No Hit Behind: Accelerating Lead Molecule Discovery Against Difficult Targets onWednesday, May 4 at10 a.m. ET .
Abstract: The Berkeley Lights’ Opto™ Plasma B Discovery (OPBD) 4.0 workflow enables recovery of 1000s of hits by screening up to 100,000 plasma cells, down-selection of lead candidates by functional screening, and sequencing and re-expression of >1000 functionally characterized antibodies in one week. By maximizing the diversity of antibodies through direct functional profiling of plasma cells, the OPBD 4.0 workflow allows users to tackle even the most challenging targets.
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