Company Centessa Pharmaceuticals plc

Equities

CNTA

US1523091007

Biotechnology & Medical Research

Market Closed - Nasdaq 04:00:00 2024-04-26 pm EDT 5-day change 1st Jan Change
8.92 USD -0.11% Intraday chart for Centessa Pharmaceuticals plc -15.61% +12.06%

Business Summary

Centessa Pharmaceuticals plc is a clinical-stage pharmaceutical company. The Company's advanced product candidate, SerpinPC, is a subcutaneously administered inhibitor of activated protein C (APC) being developed as a potential treatment for hemophilia. Leveraging its LockBody technology, it is developing an approach to selectively drive potent effector function activity, such as CD47 or CD3, into the tumor microenvironment (TME) while avoiding systemic toxicity. Its first LockBody product candidate, LB101, is a conditionally tetravalent PD-L1xCD47 bispecific monoclonal antibody used in solid tumors. Its other programs consist of earlier-stage preclinical assets, including ORX750, an orally administered, selective Orexin Receptor-2 (OX2R) agonist for the treatment of narcolepsy (NT1) with potential expansion into other sleep disorders, and MGX292, a protein-engineered variant of human bone morphogenetic protein 9 (BMP9) for the treatment of pulmonary arterial hypertension (PAH).

Number of employees: 76

Sales per Business

USD in Million2022Weight2023Weight Delta
Pharmaceutical
100.0 %
0 nan % 7 100.0 % -

Sales per region

USD in Million2022Weight2023Weight Delta
United Kingdom
100.0 %
0 nan % 7 100.0 % -

Managers

Managers TitleAgeSince
Chief Executive Officer 47 20-12-31
Director of Finance/CFO 53 21-02-28
Chief Tech/Sci/R&D Officer - 23-10-02
Chief Operating Officer - 23-10-02
Chief Administrative Officer 56 21-03-31
Investor Relations Contact - 22-05-31
General Counsel - 22-06-30
Corporate Officer/Principal - 23-02-28
General Counsel 43 21-01-31
Human Resources Officer 57 22-11-29

Members of the board

Members of the board TitleAgeSince
Director/Board Member 61 21-02-22
Chairman 54 20-10-31
Director/Board Member 51 20-12-31
Chief Executive Officer 47 20-12-31
Director/Board Member 45 21-02-22
Director/Board Member - 20-12-31
Director/Board Member 68 21-05-16
Director/Board Member 70 22-06-30

Share class

VoteQuantityFree-FloatCompany-owned sharesTotal Float
Stock A 1 100,305,850 88,670,371 ( 88.40 %) 0 88.40 %

Shareholders

NameEquities%Valuation
Medicxi Ventures (Jersey) Ltd.
20.45 %
19,963,157 20.45 % 226 M $
General Atlantic LLC
9.917 %
9,681,818 9.917 % 109 M $
BVF, Inc.
8.988 %
8,774,570 8.988 % 99 M $
EcoR1 Capital, LLC
5.755 %
5,618,779 5.755 % 63 M $
VV Manager LLC
4.027 %
3,931,818 4.027 % 44 M $
OUP Management Co. LLC
3.009 %
2,937,615 3.009 % 33 M $
Adage Capital Partners GP LLC
2.966 %
2,896,128 2.966 % 33 M $
Fidelity Management & Research Co. LLC
2.855 %
2,787,194 2.855 % 31 M $
T Rowe Price Associates, Inc. (13F Subfiler)
2.601 %
2,539,464 2.601 % 29 M $
Octagon Capital Advisors LP
2.110 %
2,060,100 2.110 % 23 M $
NameEquities%Valuation
General Atlantic LLC
10.77 %
9,681,818 10.77 % 109 M $
990,290 1.102 % 11 M $
929,353 1.034 % 11 M $
906,187 1.008 % 10 M $
783,066 0.8710 % 9 M $
David Chao
0.3037 %
272,986 0.3037 % 3 M $
265,111 0.2949 % 3 M $
218,030 0.2425 % 2 M $
188,244 0.2094 % 2 M $
Tia Bush
0.1892 %
170,064 0.1892 % 2 M $

Company contact information

Centessa Pharmaceuticals Plc

1 Ashley Road 3rd Floor

WA14 2DT, Altrincham

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http://www.centessa.com
address Centessa Pharmaceuticals plc(CNTA)
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